Lidocaine alleviates morphine tolerance via AMPK-SOCS3-dependent neuroinflammation suppression in the spinal cord

[1]  L. Young,et al.  Toll-like Receptor 4 Mediates Morphine-Induced Neuroinflammation and Tolerance via Soluble Tumor Necrosis Factor Signaling , 2017, Neuropsychopharmacology.

[2]  C. Qian,et al.  Metformin reduces morphine tolerance by inhibiting microglial-mediated neuroinflammation , 2016, Journal of Neuroinflammation.

[3]  N. Stevenson,et al.  SOCS3 revisited: a broad regulator of disease, now ready for therapeutic use? , 2016, Cellular and Molecular Life Sciences.

[4]  Liang Hu,et al.  Procyanidins alleviates morphine tolerance by inhibiting activation of NLRP3 inflammasome in microglia , 2016, Journal of Neuroinflammation.

[5]  Luyong Zhang,et al.  Telmisartan prevention of LPS-induced microglia activation involves M2 microglia polarization via CaMKKβ-dependent AMPK activation , 2015, Brain, Behavior, and Immunity.

[6]  K. Hassanzadeh,et al.  Neuroprotection of donepezil against morphine-induced apoptosis is mediated through Toll-like receptors. , 2015, European journal of pharmacology.

[7]  S. Ghanbarzadeh,et al.  Protective effect of pioglitazone on morphine-induced neuroinflammation in the rat lumbar spinal cord , 2015, Journal of Biomedical Science.

[8]  Wei Jiang,et al.  Involvement of neuronal TGF‐β activated kinase 1 in the development of tolerance to morphine‐induced antinociception in rat spinal cord , 2015, British journal of pharmacology.

[9]  G. Zhang,et al.  Resveratrol reduces morphine tolerance by inhibiting microglial activation via AMPK signalling , 2014, European journal of pain.

[10]  Xuechu Zhen,et al.  CaMKKβ-dependent activation of AMP-activated protein kinase is critical to suppressive effects of hydrogen sulfide on neuroinflammation. , 2014, Antioxidants & redox signaling.

[11]  C. Nicol,et al.  Toll-Like Receptor 4 Mutant and Null Mice Retain Morphine-Induced Tolerance, Hyperalgesia, and Physical Dependence , 2014, PloS one.

[12]  M. Rottenberg,et al.  SOCS3, a Major Regulator of Infection and Inflammation , 2014, Front. Immunol..

[13]  V. Tiwari,et al.  Opioid receptor-triggered spinal mTORC1 activation contributes to morphine tolerance and hyperalgesia. , 2014, The Journal of clinical investigation.

[14]  A. Murphy,et al.  Blockade of Toll-Like Receptor 4 Attenuates Morphine Tolerance and Facilitates the Pain Relieving Properties of Morphine , 2013, The Journal of Neuroscience.

[15]  Long-chuan Yu,et al.  Expression of calcitonin gene-related peptide receptor subunits in cultured neurons following morphine treatment , 2013, Neuroscience Letters.

[16]  K. Hassanzadeh,et al.  Repeated central administration of selegiline attenuated morphine physical dependence in rat , 2013, Pharmacological reports : PR.

[17]  Honglin Wang,et al.  Lidocaine inhibits staphylococcal enterotoxin-stimulated activation of peripheral blood mononuclear cells from patients with atopic dermatitis , 2013, Archives of Dermatological Research.

[18]  M. Peppelenbosch,et al.  Targeting LKB1 signaling in cancer. , 2013, Biochimica et biophysica acta.

[19]  K. Fukuda,et al.  Microglial activation involved in morphine tolerance is not mediated by toll-like receptor 4 , 2013, Journal of Anesthesia.

[20]  M. von Zastrow,et al.  Regulation of µ-Opioid Receptors: Desensitization, Phosphorylation, Internalization, and Tolerance , 2013, Pharmacological Reviews.

[21]  C. Cunningham Microglia and neurodegeneration: The role of systemic inflammation , 2013, Glia.

[22]  E. Benveniste,et al.  SOCS3 Deficiency Promotes M1 Macrophage Polarization and Inflammation , 2012, The Journal of Immunology.

[23]  R. Marcus,et al.  Systemic Lidocaine to Improve Postoperative Quality of Recovery After Ambulatory Laparoscopic Surgery , 2012, Anesthesia and analgesia.

[24]  A. Means,et al.  Calcium/Calmodulin-dependent Protein Kinase Kinase 2: Roles in Signaling and Pathophysiology* , 2012, The Journal of Biological Chemistry.

[25]  Traci L. Marin,et al.  Glucagon regulates ACC activity in adipocytes through the CAMKKβ/AMPK pathway. , 2012, American journal of physiology. Endocrinology and metabolism.

[26]  L. Harrington,et al.  Signal transducer and activator of transcription-3/suppressor of cytokine signaling-3 (STAT3/SOCS3) axis in myeloid cells regulates neuroinflammation , 2012, Proceedings of the National Academy of Sciences.

[27]  Z. Zuo,et al.  Delayed Treatment with Lidocaine Reduces Mouse Microglial Cell Injury and Cytokine Production After Stimulation with Lipopolysaccharide and Interferon &ggr; , 2012, Anesthesia and analgesia.

[28]  K. Inoki,et al.  AMPK and mTOR in cellular energy homeostasis and drug targets. , 2012, Annual review of pharmacology and toxicology.

[29]  S. Amato,et al.  Bioenergy sensing in the brain , 2011, Cell cycle.

[30]  S. Maier,et al.  Exploring the Neuroimmunopharmacology of Opioids: An Integrative Review of Mechanisms of Central Immune Signaling and Their Implications for Opioid Analgesia , 2011, Pharmacological Reviews.

[31]  Y. Kamikubo,et al.  Lidocaine Attenuates the Development of Diabetic-Induced Tactile Allodynia by Inhibiting Microglial Activation , 2011, Anesthesia and analgesia.

[32]  Shiyuan Xu,et al.  Bupivacaine Induces Reactive Oxygen Species Production via Activation of the AMP-Activated Protein Kinase-Dependent Pathway , 2011, Pharmacology.

[33]  Chih-Shung Wong,et al.  Etanercept Restores the Antinociceptive Effect of Morphine and Suppresses Spinal Neuroinflammation in Morphine-Tolerant Rats , 2011, Anesthesia and analgesia.

[34]  C. Bernstein,et al.  AMPK agonist downregulates innate and adaptive immune responses in TNBS-induced murine acute and relapsing colitis. , 2010, Biochemical pharmacology.

[35]  F. Cunha,et al.  Effects of lidocaine infusion during experimental endotoxemia in horses. , 2010, Journal of veterinary internal medicine.

[36]  L. McCullough,et al.  Effects of AMP-Activated Protein Kinase in Cerebral Ischemia , 2010, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[37]  S. Maier,et al.  Evidence that opioids may have toll-like receptor 4 and MD-2 effects , 2010, Brain, Behavior, and Immunity.

[38]  Junfa Li,et al.  Systemic administration of lidocaine reduces morphine requirements and postoperative pain of patients undergoing thoracic surgery after propofol–remifentanil-based anaesthesia , 2010, European journal of anaesthesiology.

[39]  C. Woolf,et al.  Central sensitization: a generator of pain hypersensitivity by central neural plasticity. , 2009, The journal of pain : official journal of the American Pain Society.

[40]  Shailendra Giri,et al.  Metformin Attenuated the Autoimmune Disease of the Central Nervous System in Animal Models of Multiple Sclerosis1 , 2009, The Journal of Immunology.

[41]  L. Maia,et al.  The use of lidocaine as an anti-inflammatory substance: a systematic review. , 2009, Journal of dentistry.

[42]  Masato Kubo,et al.  SOCS proteins, cytokine signalling and immune regulation , 2007, Nature Reviews Immunology.

[43]  R. Medzhitov,et al.  Phosphoinositide-Mediated Adaptor Recruitment Controls Toll-like Receptor Signaling , 2006, Cell.

[44]  I. Goshen,et al.  Interleukin-1 antagonizes morphine analgesia and underlies morphine tolerance , 2005, Pain.

[45]  S. Miller,et al.  Microglia Initiate Central Nervous System Innate and Adaptive Immune Responses through Multiple TLRs1 , 2004, The Journal of Immunology.

[46]  J. Linden,et al.  Lidocaine Enhances G&agr;i Protein Function , 2003 .

[47]  Pamela L. Follett,et al.  Activation of innate immunity in the CNS triggers neurodegeneration through a Toll-like receptor 4-dependent pathway , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[48]  R. Flavell,et al.  The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors , 2002, Nature.

[49]  A. Dahlström,et al.  Treatment of distal colitis with local anaesthetic agents. , 2002, Pharmacology & toxicology.

[50]  B. Yoburn,et al.  Role of cAMP‐dependent protein kinase (PKA) in opioid agonist‐induced μ‐opioid receptor downregulation and tolerance in mice , 2000, Synapse.

[51]  N. Maekawa,et al.  Does Early Posttreatment with Lidocaine Attenuate Endotoxin-induced Acute Lung Injury in Rabbits? , 1995 .

[52]  J. Hawkins,et al.  The pharmacology of local anesthetics. , 1995, Ontario dentist.

[53]  H. Asl EFFECTS OF KETAMINE AND MIDAZOLAM ON MORPHINE INDUCED DEPENDENCE AND TOLERANCE IN MICE , 2004 .

[54]  B. Habibi-asl,et al.  Effects of ketamine and midazolam on morphine induced dependence and tolerance in mice , 2004 .

[55]  J. Linden,et al.  Lidocaine enhances Galphai protein function. , 2003, Anesthesiology.