Leukocyte counts in children with sickle cell disease. Comparative values in the steady state, vaso-occlusive crisis, and bacterial infection.
暂无分享,去创建一个
Total and differential WBC counts were measured in 88 children with sickle cell hemoglobinopathies during the steady state, vaso-occlusive crisis, and bacterial infection. Steady state leukocyte values were lower than anticipated on the basis of currently available information. Total and segmented leukocyte numbers were greatly increased during vaso-occlusive crisis and infection, but only with bacterial infection was there a consistent increase in bands or nonsegmented leukocytes (mean, 4,580/microliter). On the basis of these data we believe that total and differential leukocyte counts are of value for identifying those children with potentially serious bacterial infections.
[1] A. Smith,et al. Hemophilus influenzae bacteremia in children with sickle cell disease. , 1976, The Journal of pediatrics.
[2] J. Todd. Childhood infections. Diagnostic value of peripheral white blood cell and differential cell counts. , 1974, American journal of diseases of children.
[3] E. Barrett-Connor. Pneumonia and pulmonary infarction in sickle cell anemia. , 1973, JAMA.
[4] M. Mufson,et al. Diplococcus pneumoniae infections in children with sickle cell anemia. , 1972, American journal of diseases of children.