Generalized Image Reconstruction in Optical Coherence Tomography Using Redundant and Non-Uniformly-Spaced Samples

In this paper, we use Frame Theory to develop a generalized OCT image reconstruction method using redundant and non-uniformly spaced frequency domain samples that includes using non-redundant and uniformly spaced samples as special cases. We also correct an important theoretical error in the previously reported results related to OCT image reconstruction using the Non-uniform Discrete Fourier Transform (NDFT). Moreover, we describe an efficient method to compute our corrected reconstruction transform, i.e., a scaled NDFT, using the Fast Fourier Transform (FFT). Finally, we demonstrate different advantages of our generalized OCT image reconstruction method by achieving (1) theoretically corrected OCT image reconstruction directly from non-uniformly spaced frequency domain samples; (2) a novel OCT image reconstruction method with a higher signal-to-noise ratio (SNR) using redundant frequency domain samples. Our new image reconstruction method is an improvement of OCT technology, so it could benefit all OCT applications.

[1]  J. Fujimoto,et al.  Optical frequency-domain reflectometry using rapid wavelength tuning of a Cr4+:forsterite laser. , 1997, Optics letters.

[2]  Xiaofei Wang,et al.  A Deep Learning Approach to Denoise Optical Coherence Tomography Images of the Optic Nerve Head , 2018, Scientific Reports.

[3]  Peng Bu,et al.  Speckle reduction in parallel optical coherence tomography by spatial compounding , 2013 .

[4]  Michael L. Oelze,et al.  Speckle Reduction for Ultrasonic Imaging Using Frequency Compounding and Despeckling Filters along with Coded Excitation and Pulse Compression , 2012 .

[5]  Zhihua Ding,et al.  Hybrid averaging offers high-flow contrast by cost apportionment among imaging time, axial, and lateral resolution in optical coherence tomography angiography. , 2016, Optics letters.

[6]  Alin Achim,et al.  Novel Bayesian multiscale method for speckle removal in medical ultrasound images , 2001, IEEE Transactions on Medical Imaging.

[7]  Joachim Hornegger,et al.  Wavelet denoising of multiframe optical coherence tomography data , 2012, Biomedical optics express.

[8]  Alin Achim,et al.  SAR image denoising via Bayesian wavelet shrinkage based on heavy-tailed modeling , 2003, IEEE Trans. Geosci. Remote. Sens..

[9]  Caroline Boudoux,et al.  Simple and robust calibration procedure for k-linearization and dispersion compensation in optical coherence tomography , 2019, Journal of biomedical optics.

[10]  Juan Ruiz,et al.  Fuzzy anisotropic diffusion for speckle filtering , 2001, 2001 IEEE International Conference on Acoustics, Speech, and Signal Processing. Proceedings (Cat. No.01CH37221).

[11]  Changho Chong,et al.  High-Speed Wavelength-Swept Laser Source With High-Linearity Sweep for Optical Coherence Tomography , 2008, IEEE Journal of Selected Topics in Quantum Electronics.

[12]  Hossein Rabbani,et al.  Speckle Noise Reduction in Optical Coherence Tomography Using Two-dimensional Curvelet-based Dictionary Learning , 2017, Journal of medical signals and sensors.

[13]  Alexander Wong,et al.  General Bayesian estimation for speckle noise reduction in optical coherence tomography retinal imagery. , 2010, Optics express.

[14]  Pilun Kim,et al.  Numerical-Sampling-Functionalized Real-Time Index Regulation for Direct k-Domain Calibration in Spectral Domain Optical Coherence Tomography , 2018 .

[15]  Andrew M Rollins,et al.  Speckle reduction in optical coherence tomography using angular compounding by B-scan Doppler-shift encoding. , 2009, Journal of biomedical optics.

[16]  Martin F. Kraus,et al.  Split-spectrum amplitude-decorrelation angiography with optical coherence tomography , 2012, Optics express.

[17]  Changhuei Yang,et al.  Sensitivity advantage of swept source and Fourier domain optical coherence tomography. , 2003, Optics express.

[18]  Massoud Motamedi,et al.  Retinal optical coherence tomography image enhancement via shrinkage denoising using double-density dual-tree complex wavelet transform , 2012, Journal of biomedical optics.

[19]  J. Fujimoto,et al.  Amplified, frequency swept lasers for frequency domain reflectometry and OCT imaging: design and scaling principles. , 2005, Optics express.

[20]  S. Sherif,et al.  Statistics of the depth-scan photocurrent in time-domain optical coherence tomography. , 2008, Journal of the Optical Society of America. A, Optics, image science, and vision.

[21]  H. Ermert,et al.  Ultrasound breast imaging using Full Angle Spatial Compounding: In-vivo results , 2008, 2008 IEEE Ultrasonics Symposium.

[22]  Noise of supercontinuum sources in spectral domain optical coherence tomography , 2019, Journal of the Optical Society of America B.

[23]  S. Mallat A wavelet tour of signal processing , 1998 .

[24]  B. Bouma,et al.  Improved signal-to-noise ratio in spectral-domain compared with time-domain optical coherence tomography. , 2003, Optics letters.

[25]  J. Schmitt,et al.  Speckle in optical coherence tomography. , 1999, Journal of biomedical optics.

[26]  Leong Keey Seah,et al.  An efficient phase analysis-based wavenumber linearization scheme for swept source optical coherence tomography systems , 2015 .

[27]  Zhaoxia Yu,et al.  Speckle attenuation in optical coherence tomography by curvelet shrinkage. , 2009, Optics letters.

[28]  Zhihua Ding,et al.  Angular compounding by full-channel B-scan modulation encoding for optical coherence tomography speckle reduction , 2016, Journal of biomedical optics.

[29]  Mohamed-Jalal Fadili,et al.  Multiplicative Noise Removal Using L1 Fidelity on Frame Coefficients , 2008, Journal of Mathematical Imaging and Vision.

[30]  Mrityunjay Kumar,et al.  Sparse Image and Signal Processing: Wavelets, Curvelets, Morphological Diversity, by Jean-Luc Starck, Fionn Murtagh, and Jalal M. Fadili , 2007 .

[31]  Bin Liu,et al.  Real-time and high-performance calibration method for high-speed swept-source optical coherence tomography. , 2010, Journal of biomedical optics.

[32]  Hongming Zhang,et al.  Speckle noise reduction algorithm with total variation regularization in optical coherence tomography. , 2015, Optics express.

[33]  Mark E. Brezinski,et al.  Evaluation of the adaptive speckle suppression filter for coronary optical coherence tomography imaging , 2000, IEEE Transactions on Medical Imaging.

[34]  A. Fercher,et al.  Measurement of intraocular distances by backscattering spectral interferometry , 1995 .

[35]  Jin U. Kang,et al.  Robust spectral-domain optical coherence tomography speckle model and its cross-correlation coefficient analysis. , 2013, Journal of the Optical Society of America. A, Optics, image science, and vision.

[36]  Sébastien Vergnole,et al.  Experimental validation of an optimized signal processing method to handle non-linearity in swept-source optical coherence tomography. , 2010, Optics express.

[37]  A. Fercher,et al.  Wavelength-tuning interferometry of intraocular distances. , 1997, Applied optics.

[38]  Birgit Wirtz,et al.  Optical Electronics In Modern Communications , 2016 .

[39]  Kang Zhang,et al.  Graphics processing unit accelerated non-uniform fast Fourier transform for ultrahigh-speed, real-time Fourier-domain OCT , 2010, Optics express.

[40]  V Blazek,et al.  Chirp optical coherence tomography of layered scattering media. , 1998, Journal of biomedical optics.

[41]  A. Fercher,et al.  Performance of fourier domain vs. time domain optical coherence tomography. , 2003, Optics express.

[42]  A. Fercher,et al.  Speckle reduction in optical coherence tomography by frequency compounding. , 2003, Journal of biomedical optics.

[43]  Scott T. Acton,et al.  Speckle reducing anisotropic diffusion , 2002, IEEE Trans. Image Process..

[44]  Zhihua Ding,et al.  Spectral phase based k-domain interpolation for uniform sampling in swept-source optical coherence tomography. , 2011, Optics express.

[45]  Eric L Yuan,et al.  Quantitative classification of eyes with and without intermediate age-related macular degeneration using optical coherence tomography. , 2014, Ophthalmology.

[46]  S H Yun,et al.  Motion artifacts in optical coherence tomography with frequency-domain ranging. , 2004, Optics express.

[47]  Shoude Chang,et al.  Swept Source Optical Coherence Tomography with Nonuniform Frequency Domain Sampling , 2008 .

[48]  John Minkoff,et al.  Signal Processing Fundamentals and Applications for Communications and Sensing Systems , 2002 .

[49]  J. Fujimoto,et al.  Optical coherence tomography using a frequency-tunable optical source. , 1997, Optics letters.

[50]  J. Fujimoto,et al.  Optical Coherence Tomography , 1991 .

[51]  Qiang Guo,et al.  Noise Reduction of Swept-Source Optical Coherence Tomography via Compressed Sensing , 2018, IEEE Photonics Journal.

[52]  T. Loupas,et al.  An adaptive weighted median filter for speckle suppression in medical ultrasonic images , 1989 .

[53]  Yu Gan,et al.  Phase-noise analysis of swept-source optical coherence tomography systems. , 2017, Optics letters.