A novel radiofluorinated agouti-related protein for tumor angiogenesis imaging

[1]  Zhen Cheng,et al.  Protein scaffold-based molecular probes for cancer molecular imaging , 2011, Amino Acids.

[2]  Norelle L Daly,et al.  Bioactive cystine knot proteins. , 2011, Current opinion in chemical biology.

[3]  R. Kimura,et al.  Functional Mutation of Multiple Solvent-Exposed Loops in the Ecballium elaterium Trypsin Inhibitor-II Cystine Knot Miniprotein , 2011, PloS one.

[4]  Kai Chen,et al.  18F-Labeled Galacto and PEGylated RGD Dimers for PET Imaging of αvβ3 Integrin Expression , 2010, Molecular Imaging and Biology.

[5]  Jinha M. Park,et al.  64Cu-Labeled Affibody Molecules for Imaging of HER2 Expressing Tumors , 2010, Molecular Imaging and Biology.

[6]  H. Kolmar Engineered cystine-knot miniproteins for diagnostic applications , 2010, Expert review of molecular diagnostics.

[7]  S. Gambhir,et al.  A dual-labeled knottin peptide for PET and near-infrared fluorescence imaging of integrin expression in living subjects. , 2010, Bioconjugate chemistry.

[8]  J. Sosman,et al.  A randomized phase 2 study of etaracizumab, a monoclonal antibody against integrin αvβ3, ± dacarbazine in patients with stage IV metastatic melanoma , 2010, Cancer.

[9]  Adam P. Silverman,et al.  Evaluation of a 64Cu-Labeled Cystine-Knot Peptide Based on Agouti-Related Protein for PET of Tumors Expressing αvβ3 Integrin , 2010, Journal of Nuclear Medicine.

[10]  S. Gambhir,et al.  An engineered knottin peptide labeled with 18F for PET imaging of integrin expression. , 2009, Bioconjugate chemistry.

[11]  R. Kimura,et al.  Engineered cystine knot peptides that bind αvβ3, αvβ5, and α5β1 integrins with low‐nanomolar affinity , 2009, Proteins.

[12]  S. Gambhir,et al.  A 2-Helix Small Protein Labeled with 68Ga for PET Imaging of HER2 Expression , 2009, Journal of Nuclear Medicine.

[13]  S. Gambhir,et al.  Engineered knottin peptides: a new class of agents for imaging integrin expression in living subjects. , 2009, Cancer research.

[14]  Jennifer L. Lahti,et al.  Engineered cystine-knot peptides that bind alpha(v)beta(3) integrin with antibody-like affinities. , 2009, Journal of molecular biology.

[15]  S. Gambhir,et al.  Small-Animal PET Imaging of Human Epidermal Growth Factor Receptor Type 2 Expression with Site-Specific 18F-Labeled Protein Scaffold Molecules , 2008, Journal of Nuclear Medicine.

[16]  C. Vanhove,et al.  SPECT Imaging with 99mTc-Labeled EGFR-Specific Nanobody for In Vivo Monitoring of EGFR Expression , 2008, Molecular Imaging and Biology.

[17]  Nadia Harbeck,et al.  Patterns of αvβ3 Expression in Primary and Metastatic Human Breast Cancer as Shown by 18F-Galacto-RGD PET , 2008, Journal of Nuclear Medicine.

[18]  S. Gambhir,et al.  Small-Animal PET of Melanocortin 1 Receptor Expression Using a 18F-Labeled α-Melanocyte-Stimulating Hormone Analog , 2007, Journal of Nuclear Medicine.

[19]  S. Gambhir,et al.  64Cu-labeled alpha-melanocyte-stimulating hormone analog for microPET imaging of melanocortin 1 receptor expression. , 2007, Bioconjugate chemistry.

[20]  S. Ogren,et al.  Down-regulated expression of agouti-related protein (AGRP) mRNA in the hypothalamic arcuate nucleus of hyperphagic and obese tub/tub mice. , 2004, Brain research. Molecular brain research.

[21]  M. Schwaiger,et al.  Radiotracer-based strategies to image angiogenesis. , 2003, The quarterly journal of nuclear medicine : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology.

[22]  Sibylle Ziegler,et al.  Noninvasive Imaging of αvβ3 Integrin Expression Using 18F-labeled RGD-containing Glycopeptide and Positron Emission Tomography , 2001 .

[23]  G. Barsh,et al.  Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein. , 1997, Science.

[24]  J. Shutter,et al.  Hypothalamic expression of ART, a novel gene related to agouti, is up-regulated in obese and diabetic mutant mice. , 1997, Genes & development.

[25]  A. A. Knecht EVALUATION OF A , 1972 .

[26]  M. Schwaiger,et al.  [18F]Galacto-RGD: synthesis, radiolabeling, metabolic stability, and radiation dose estimates. , 2004, Bioconjugate chemistry.

[27]  Renhao Li,et al.  Use of phage display to probe the evolution of binding specificity and affinity in integrins. , 2003, Protein engineering.

[28]  M. Schwaiger,et al.  Noninvasive imaging of alpha(v)beta3 integrin expression using 18F-labeled RGD-containing glycopeptide and positron emission tomography. , 2001, Cancer research.