Effect of Laparoscopic‐assisted Gastropexy on Gastrointestinal Transit Time in Dogs

Background Prophylactic gastropexy has been promoted as a means of preventing gastric volvulus during gastric dilatation and volvulus (GDV) syndrome. Little is known about the impact of gastropexy on gastrointestinal transit time. Hypothesis Laparoscopic‐assisted gastropexy (LAG) will not alter gastrointestinal transit times when comparing gastric (GET), small and large bowel (SLBTT), and whole gut transit times (TTT) before and after surgery. Animals 10 healthy client‐owned large‐breed dogs. Methods Prospective clinical trial. Before surgery, all dogs underwent physical examination and diagnostic evaluation to ensure normal health status. Dogs were fed a prescription diet for 6 weeks before determination of gastrointestinal transit with a wireless motility capsule. LAG was then performed, and dogs were fed the diet for 6 additional weeks. Measurement of transit times was repeated 6 weeks after surgery. Results Ten dogs of various breeds at‐risk for GDV were enrolled. No complications were encountered associated with surgery or capsule administration. There were no significant differences in GET 429 [306–1,370] versus 541 [326–1,298] (P = 0.80), SLBTT 1,243 [841–3,070] versus 1,540 [756–2,623] (P = 0.72), or TTT 1,971 [1,205–3,469] versus 1,792 [1,234–3,343] minutes (median, range) (P = 0.65) before and after LAG. Conclusions and Clinical Importance An effect of LAG on gastrointestinal transit time was not identified, and wireless motility capsule can be safely administered in dogs after LAG.

[1]  Laura L. Nelson,et al.  Effects of prophylactic incisional gastropexy on markers of gastric motility in dogs as determined by use of a novel wireless motility device. , 2017, American journal of veterinary research.

[2]  S. Marks,et al.  Gastric malpositioning and chronic, intermittent vomiting following prophylactic gastropexy in a 20-month-old great Dane dog. , 2015, The Canadian veterinary journal = La revue veterinaire canadienne.

[3]  J. Madsen Scintigraphic assessment of gastrointestinal motility: a brief review of techniques and data interpretation , 2014, Clinical physiology and functional imaging.

[4]  C. Webb,et al.  Effect of prolonged general anesthesia with sevoflurane and laparoscopic surgery on gastric and small bowel propulsive motility and pH in dogs. , 2014, Veterinary anaesthesia and analgesia.

[5]  M. Camilleri,et al.  Evaluation of gastrointestinal transit in clinical practice: position paper of the American and European Neurogastroenterology and Motility Societies , 2011, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.

[6]  G. Hosgood,et al.  Variability associated with repeated measurements of gastrointestinal tract motility in dogs obtained by use of a wireless motility capsule system and scintigraphy. , 2010, American journal of veterinary research.

[7]  G. Hosgood,et al.  Assessment of the relationship between body weight and gastrointestinal transit times measured by use of a wireless motility capsule system in dogs. , 2010, American journal of veterinary research.

[8]  H. Parkman,et al.  Wireless Capsule Motility: Comparison of the SmartPill® GI Monitoring System with Scintigraphy for Measuring Whole Gut Transit , 2009, Digestive Diseases and Sciences.

[9]  P. Mayhew,et al.  Prospective evaluation of two intracorporeally sutured prophylactic laparoscopic gastropexy techniques compared with laparoscopic-assisted gastropexy in dogs. , 2009, Veterinary surgery : VS.

[10]  Hyojin Park,et al.  Effect of erythromycin on gastric emptying in healthy individuals assessed by radio-opaque markers and plasma acetaminophen levels , 1997, Journal of Gastroenterology.

[11]  M. Ward,et al.  Benefits of prophylactic gastropexy for dogs at risk of gastric dilatation-volvulus. , 2003, Preventive veterinary medicine.

[12]  E. Hardie,et al.  Clinical evaluation of a right-sided prophylactic gastropexy via a grid approach. , 2003, The Journal of the American Animal Hospital Association.

[13]  C. Rawlings,et al.  Prospective evaluation of laparoscopic-assisted gastropexy in dogs susceptible to gastric dilatation. , 2002, Journal of the American Veterinary Medical Association.

[14]  T. Eriksen,et al.  Comparison of the recurrence rate of gastric dilatation with or without volvulus in dogs after circumcostal gastropexy versus gastrocolopexy. , 2001, Veterinary surgery.

[15]  C. Rawlings,et al.  A rapid and strong laparoscopic-assisted gastropexy in dogs. , 2001, American journal of veterinary research.

[16]  L. Glickman,et al.  Incidence of and breed-related risk factors for gastric dilatation-volvulus in dogs. , 2000, Journal of the American Veterinary Medical Association.

[17]  J. Payne,et al.  Evaluation of percutaneous gastrostomy as a technique for permanent gastropexy. , 1997, Veterinary surgery : VS.

[18]  P. Boesiger,et al.  Evaluation of Delayed Gastric Emptying in Diabetic Patients With Autonomic Neuropathy by a New Magnetic Resonance Imaging Technique and Radio-Opaque Markers , 1996, Diabetes Care.

[19]  D. Twedt,et al.  Gastric emptying of nondigestible radiopaque markers after circumcostal gastropexy in clinically normal dogs and dogs with gastric dilatation-volvulus. , 1992, American journal of veterinary research.

[20]  van den Brom We,et al.  Gastric emptying of a radionuclide-labeled test meal after surgical correction of gastric dilatation-volvulus in dogs. , 1989 .

[21]  W. E. van den Brom,et al.  Gastric emptying of a radionuclide-labeled test meal after surgical correction of gastric dilatation-volvulus in dogs. , 1989, American journal of veterinary research.