A hospital based cross sectional study on serum LDH, Iron, TIBC and Ferritin levels in hyperthyroidism

Background: Ferritin is an iron storage protein which is present in most of the tissues. Its levels in the serum are altered in thyroid disorders and also reflects the thyroid function with any change in its level Objective: Thyroperoxidase which is dependent on iron for the synthesis of thyroid hormones. So there is an association with thyroid profile and ferritin levels. The aim of study is to investigate the changes in serum levels of ferritin and LDH in hyperthyroidism Materials and Methods: Ferritin, Iron, TIBC and LDH levels were estimated in 50 age and sex matched patients of hyperthyroidism using Thyroid profile and ferritin levels were estimated using CLIA in Mindray. Iron, TIBC and LDH levels were estimated in ERBA chem7 and the results were correlated statistically. Results: Serum ferritin levels were found to be significantly increased in patients with hyperthyroidism compared to normal subjects (p < 0.001) and TIBC levels were significantly reduced. Conclusion: Hyperthyroidism is associated with high serum ferritin levels. The estimation of serum ferritin may help in understanding the etiopathogenesis, diagnosis, and monitoring of hyperthyroid patients.