Inositol hexakisphosphate kinase products contain diphosphate and triphosphate groups.

[1]  J. Falck,et al.  Purification, Sequencing, and Molecular Identification of a Mammalian PP-InsP5 Kinase That Is Activated When Cells Are Exposed to Hyperosmotic Stress* , 2007, Journal of Biological Chemistry.

[2]  J. Otto,et al.  Cloning and Characterization of Two Human VIP1-like Inositol Hexakisphosphate and Diphosphoinositol Pentakisphosphate Kinases* , 2007, Journal of Biological Chemistry.

[3]  D. Lindner,et al.  Effect of Inositol Hexakisphosphate Kinase 2 on Transforming Growth Factor β-activated Kinase 1 and NF-κB Activation* , 2007, Journal of Biological Chemistry.

[4]  J. Otto,et al.  A Conserved Family of Enzymes That Phosphorylate Inositol Hexakisphosphate , 2007, Science.

[5]  S. Shears.  Understanding the biological significance of diphosphoinositol polyphosphates ('inositol pyrophosphates'). , 2007, Biochemical Society symposium.

[6]  R. Michell.  Evolution of the diverse biological roles of inositols. , 2007, Biochemical Society symposium.

[7]  A. R. Shenoy,et al.  Structural and biochemical analysis of the Rv0805 cyclic nucleotide phosphodiesterase from Mycobacterium tuberculosis. , 2007, Journal of molecular biology.

[8]  J. Honek,et al.  Phosphate transfer from inositol pyrophosphates InsP5PP and InsP4(PP)2: a semi-empirical investigation. , 2007, Bioorganic & medicinal chemistry letters.

[9]  A. Saiardi,et al.  Extraction and analysis of soluble inositol polyphosphates from yeast , 2006, Nature Protocols.

[10]  A. Saiardi,et al.  Inositol pyrophosphates: metabolism and signaling , 2006, Cellular and Molecular Life Sciences.

[11]  Adolfo Saiardi,et al.  Inhibition of the phosphatidylinositol 3-kinase/Akt pathway by inositol pentakisphosphate results in antiangiogenic and antitumor effects. , 2005, Cancer research.

[12]  R. Irvine.  Inositide evolution – towards turtle domination? , 2005, The Journal of physiology.

[13]  S. Snyder,et al.  Phosphorylation of Proteins by Inositol Pyrophosphates , 2004, Science.

[14]  B. González,et al.  Structure of a human inositol 1,4,5-trisphosphate 3-kinase: substrate binding reveals why it is not a phosphoinositide 3-kinase. , 2004, Molecular cell.

[15]  A. M. Riley,et al.  Inositol pentakisphosphate promotes apoptosis through the PI 3-K/Akt pathway , 2004, Oncogene.

[16]  R. Michell,et al.  Hypo-osmotic Stress Activates Plc1p-dependent Phosphatidylinositol 4,5-Bisphosphate Hydrolysis and Inositol Hexakisphosphate Accumulation in Yeast* , 2004, Journal of Biological Chemistry.

[17]  S. Shears.  How versatile are inositol phosphate kinases? , 2004, The Biochemical journal.

[18]  E. Nagata,et al.  Inositol Pyrophosphates Mediate Chemotaxis in Dictyostelium via Pleckstrin Homology Domain-PtdIns(3,4,5)P3 Interactions , 2003, Cell.

[19]  I. Wilson,et al.  Observation of an Arsenic Adduct in an Acetyl Esterase Crystal Structure* , 2003, The Journal of Biological Chemistry.

[20]  S. Snyder,et al.  Inositol pyrophosphates regulate endocytic trafficking , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[21]  G. Mayr,et al.  The human homologue of yeast ArgRIII protein is an inositol phosphate multikinase with predominantly nuclear localization. , 2002, The Biochemical journal.

[22]  J. Hegemann,et al.  A second set of loxP marker cassettes for Cre-mediated multiple gene knockouts in budding yeast. , 2002, Nucleic acids research.

[23]  E. Nagata,et al.  Identification and Characterization of a Novel Inositol Hexakisphosphate Kinase* , 2001, The Journal of Biological Chemistry.

[24]  E. Nagata,et al.  GRAB: A Physiologic Guanine Nucleotide Exchange Factor for Rab3a, which Interacts with Inositol Hexakisphosphate Kinase , 2001, Neuron.

[25]  M. Schell,et al.  Back in the water: the return of the inositol phosphates , 2001, Nature Reviews Molecular Cell Biology.

[26]  J. Caffrey,et al.  The transcriptional regulator, Arg82, is a hybrid kinase with both monophosphoinositol and diphosphoinositol polyphosphate synthase activity , 2001, FEBS letters.

[27]  S. Snyder,et al.  Mammalian inositol polyphosphate multikinase synthesizes inositol 1,4,5-trisphosphate and an inositol pyrophosphate , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[28]  S. Snyder,et al.  The Inositol Hexakisphosphate Kinase Family , 2000, Journal of Biological Chemistry.

[29]  G. Klein,et al.  neo-Inositol Polyphosphates in the AmoebaEntamoeba histolytica * , 2000, The Journal of Biological Chemistry.

[30]  G. Mayr,et al.  Diphospho-myo-inositol phosphates during the life cycle of Dictyostelium and Polysphondylium. , 2000, European journal of biochemistry.

[31]  C. Brearley,et al.  PiUS (Pi uptake stimulator) is an inositol hexakisphosphate kinase , 1999, FEBS letters.

[32]  S. Snyder,et al.  Synthesis of diphosphoinositol pentakisphosphate by a newly identified family of higher inositol polyphosphate kinases , 1999, Current Biology.

[33]  J. York,et al.  A phospholipase C-dependent inositol polyphosphate kinase pathway required for efficient messenger RNA export. , 1999, Science.

[34]  D. Davies,et al.  Three new structures of the core domain of HIV-1 integrase: an active site that binds magnesium. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[35]  J. Falck,et al.  Diphospho‐myo‐inositol phosphates in Dictyostelium and Polysphondylium: identification of a new bisdiphospho‐myo‐inositol tetrakisphosphate , 1998, FEBS letters.

[36]  G. Mayr,et al.  Biological variability in the structures of diphosphoinositol polyphosphates in Dictyostelium discoideum and mammalian cells. , 1997, The Biochemical journal.

[37]  J. Falck,et al.  Diphospho-myo-inositol phosphates from Dictyostelium identified as D-6-diphospho-myo-inositol pentakisphosphate and D-5,6-bisdiphospho-myo-inositol tetrakisphosphate. , 1997, The Biochemical journal.

[38]  Thomas Fiedler,et al.  A new efficient gene disruption cassette for repeated use in budding yeast , 1996, Nucleic Acids Res..

[39]  R. Eujen,et al.  Structures of diphospho-myo-inositol pentakisphosphate and bisdiphospho-myo-inositol tetrakisphosphate from Dictyostelium resolved by NMR analysis. , 1996, The Biochemical journal.

[40]  S. Snyder,et al.  Purified inositol hexakisphosphate kinase is an ATP synthase: diphosphoinositol pentakisphosphate as a high-energy phosphate donor. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[41]  M. Bembenek,et al.  Inhibition of Clathrin Assembly by High Affinity Binding of Specific Inositol Polyphosphates to the Synapse-specific Clathrin Assembly Protein AP-3 (*) , 1995, The Journal of Biological Chemistry.

[42]  S. Shears,et al.  Turnover of inositol pentakisphosphates, inositol hexakisphosphate and diphosphoinositol polyphosphates in primary cultured hepatocytes. , 1993, The Biochemical journal.

[43]  F. Menniti,et al.  Turnover of inositol polyphosphate pyrophosphates in pancreatoma cells. , 1993, The Journal of biological chemistry.

[44]  K. Khoo,et al.  The detection, purification, structural characterization, and metabolism of diphosphoinositol pentakisphosphate(s) and bisdiphosphoinositol tetrakisphosphate(s). , 1993, The Journal of biological chemistry.

[45]  K G Oliver,et al.  Inositol phosphates and cell signaling: new views of InsP5 and InsP6. , 1993, Trends in biochemical sciences.

[46]  M. J. Berridge,et al.  Release of Ca2+ from a nonmitochondrial intracellular store in pancreatic acinar cells by inositol-1,4,5-trisphosphate , 1983, Nature.