The HLA ligandome of oropharyngeal squamous cell carcinomas reveals shared tumour-exclusive peptides for semi-personalised vaccination
暂无分享,去创建一个
H. Kestler | O. Kohlbacher | J. Kraus | L. Bichmann | D. Fürst | J. Walz | P. Schuler | J. Doescher | S. Laban | C. Brunner | M. Bens | J. Greve | J. Mytilineos | M. Theodoraki | L. Mühlenbruch | M. Dubbelaar | A. von Witzleben | Hans-Georg Rammensee | J. Ezić | Daphne Engelhardt | Jaya Thomas | Thomas K. Hoffmann | Tsima Abou-Kors | H. Rammensee
[1] J. J. Lee,et al. Phase II Clinical Trial of Neoadjuvant and Adjuvant Pembrolizumab in Resectable Local-Regionally Advanced Head and Neck Squamous Cell Carcinoma. , 2022, Clinical cancer research : an official journal of the American Association for Cancer Research.
[2] A. Broeks,et al. Neoadjuvant immunotherapy with nivolumab and ipilimumab induces major pathological responses in patients with head and neck squamous cell carcinoma , 2021, Nature Communications.
[3] Silke D. Kühlwein,et al. Erratum to: Analysis, identification and visualization of subgroups in genomics , 2021, Briefings in Bioinformatics.
[4] C. Paweletz,et al. Neoadjuvant and Adjuvant Nivolumab and Lirilumab in Patients with Recurrent, Resectable Squamous Cell Carcinoma of the Head and Neck , 2021, Clinical Cancer Research.
[5] D. Kallogjeri,et al. Enhanced pathologic tumor response with two cycles of neoadjuvant pembrolizumab in surgically resectable, locally advanced HPV-negative head and neck squamous cell carcinoma (HNSCC). , 2021 .
[6] Hans A Kestler,et al. Analysis, identification and visualization of subgroups in genomics , 2020, Briefings Bioinform..
[7] David A Hildeman,et al. PD1 blockade enhances K+ channel activity, Ca2+ signaling, and migratory ability in cytotoxic T lymphocytes of patients with head and neck cancer , 2020, Journal for ImmunoTherapy of Cancer.
[8] H. Iro,et al. Safety and efficacy of single cycle induction treatment with cisplatin/docetaxel/ durvalumab/tremelimumab in locally advanced HNSCC: first results of CheckRad-CD8 , 2020, Journal for ImmunoTherapy of Cancer.
[9] R. Tishler,et al. Neoadjuvant Nivolumab or Nivolumab Plus Ipilimumab in Untreated Oral Cavity Squamous Cell Carcinoma: A Phase 2 Open-Label Randomized Clinical Trial. , 2020, JAMA oncology.
[10] J. Utikal,et al. An RNA vaccine drives immunity in checkpoint-inhibitor-treated melanoma , 2020, Nature.
[11] Zachary L. Skidmore,et al. Neoadjuvant and Adjuvant Pembrolizumab in Resectable Locally Advanced, Human Papillomavirus–Unrelated Head and Neck Cancer: A Multicenter, Phase II Trial , 2020, Clinical Cancer Research.
[12] V. Grégoire,et al. Pembrolizumab given concomitantly with chemoradiation and as maintenance therapy for locally advanced head and neck squamous cell carcinoma: KEYNOTE-412. , 2020, Future oncology.
[13] H. Rammensee,et al. Integrative -omics and HLA-ligandomics analysis to identify novel drug targets for ccRCC immunotherapy , 2020, Genome Medicine.
[14] Andrew R. Jones,et al. Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools , 2019, Nucleic Acids Res..
[15] D. Jäger,et al. Patterns of antibody responses to nonviral cancer antigens in head and neck squamous cell carcinoma patients differ by human papillomavirus status , 2019, International journal of cancer.
[16] Hung-Ming Wang,et al. Pembrolizumab alone or with chemotherapy versus cetuximab with chemotherapy for recurrent or metastatic squamous cell carcinoma of the head and neck (KEYNOTE-048): a randomised, open-label, phase 3 study , 2019, The Lancet.
[17] H. Rammensee,et al. The HLA Ligand Atlas. A resource of natural HLA ligands presented on benign tissues , 2019, bioRxiv.
[18] D. Jäger,et al. Antibody Responses to Cancer Antigens Identify Patients with a Poor Prognosis among HPV-Positive and HPV-Negative Head and Neck Squamous Cell Carcinoma Patients , 2019, Clinical Cancer Research.
[19] H. Rammensee,et al. Multi-omics discovery of exome-derived neoantigens in hepatocellular carcinoma , 2019, Genome medicine.
[20] O. V. Matorin,et al. Pembrolizumab versus methotrexate, docetaxel, or cetuximab for recurrent or metastatic head-and-neck squamous cell carcinoma (KEYNOTE-040): a randomised, open-label, phase 3 study , 2019, The Lancet.
[21] Young Uk Kim,et al. Combining Immune Checkpoint Blockade and Tumor-Specific Vaccine for Patients With Incurable Human Papillomavirus 16–Related Cancer: A Phase 2 Clinical Trial , 2019, JAMA oncology.
[22] Chih-Chiang Tsou,et al. The HLA ligandome landscape of chronic myeloid leukemia delineates novel T-cell epitopes for immunotherapy. , 2018, Blood.
[23] Martin Eisenacher,et al. The PRIDE database and related tools and resources in 2019: improving support for quantification data , 2018, Nucleic Acids Res..
[24] Alessandro Sette,et al. The Immune Epitope Database (IEDB): 2018 update , 2018, Nucleic Acids Res..
[25] J. Castle,et al. Actively personalized vaccination trial for newly diagnosed glioblastoma , 2018, Nature.
[26] A. Jemal,et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries , 2018, CA: a cancer journal for clinicians.
[27] S. Rosenberg,et al. Engineered T cells targeting E7 mediate regression of human papillomavirus cancers in a murine model. , 2018, JCI insight.
[28] H. Rammensee,et al. The natural HLA ligandome of glioblastoma stem-like cells: antigen discovery for T cell-based immunotherapy , 2018, Acta Neuropathologica.
[29] S. Madhavan,et al. viGEN: An Open Source Pipeline for the Detection and Quantification of Viral RNA in Human Tumors , 2017, bioRxiv.
[30] Oliver Kohlbacher,et al. The immunopeptidomic landscape of ovarian carcinomas , 2017, Proceedings of the National Academy of Sciences.
[31] S. H. van der Burg,et al. Intratumoral HPV16-Specific T Cells Constitute a Type I–Oriented Tumor Microenvironment to Improve Survival in HPV16-Driven Oropharyngeal Cancer , 2017, Clinical Cancer Research.
[32] B. Howie,et al. Landscape of immunogenic tumor antigens in successful immunotherapy of virally induced epithelial cancer , 2017, Science.
[33] C. Compton,et al. The Eighth Edition AJCC Cancer Staging Manual: Continuing to build a bridge from a population‐based to a more “personalized” approach to cancer staging , 2017, CA: a cancer journal for clinicians.
[34] Brian O'Sullivan,et al. Head and neck cancers—major changes in the American Joint Committee on cancer eighth edition cancer staging manual , 2017, CA: a cancer journal for clinicians.
[35] J. Radford. Nivolumab for recurrent squamous-cell carcinoma of the head and neck , 2016, BDJ.
[36] Nicolai J. Birkbak,et al. Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade , 2016, Science.
[37] C. Melief,et al. Vaccines for established cancer: overcoming the challenges posed by immune evasion , 2016, Nature Reviews Cancer.
[38] Morten Nielsen,et al. Gapped sequence alignment using artificial neural networks: application to the MHC class I system , 2016, Bioinform..
[39] Oliver Kohlbacher,et al. The antigenic landscape of multiple myeloma: mass spectrometry (re)defines targets for T-cell-based immunotherapy. , 2015, Blood.
[40] J. Wolchok,et al. Genetic basis for clinical response to CTLA-4 blockade in melanoma. , 2014, The New England journal of medicine.
[41] R. Emerson,et al. PD-1 blockade induces responses by inhibiting adaptive immune resistance , 2014, Nature.
[42] J. Mariette,et al. jvenn: an interactive Venn diagram viewer , 2014, BMC Bioinformatics.
[43] S. H. van der Burg,et al. Alterations in classical and nonclassical HLA expression in recurrent and progressive HPV‐induced usual vulvar intraepithelial neoplasia and implications for immunotherapy , 2014, International journal of cancer.
[44] C Gabriel,et al. HLA typing by next-generation sequencing - getting closer to reality. , 2014, Tissue antigens.
[45] S. H. van der Burg,et al. HPV16 synthetic long peptide (HPV16-SLP) vaccination therapy of patients with advanced or recurrent HPV16-induced gynecological carcinoma, a phase II trial , 2013, Journal of Translational Medicine.
[46] H. Rammensee,et al. HLA ligandome tumor antigen discovery for personalized vaccine approach , 2013, Expert review of vaccines.
[47] S. Stevanović,et al. Biochemical large-scale identification of MHC class I ligands. , 2013, Methods in molecular biology.
[48] H. Rammensee,et al. Natural HLA class I ligands from glioblastoma: extending the options for immunotherapy , 2013, Journal of Neuro-Oncology.
[49] S. H. van der Burg,et al. Systemic and local human papillomavirus 16‐specific T‐cell immunity in patients with head and neck cancer , 2012, International journal of cancer.
[50] J. M. van der Hulst,et al. The detection of circulating human papillomavirus‐specific T cells is associated with improved survival of patients with deeply infiltrating tumors , 2011, International journal of cancer.
[51] Marc S. Cortese,et al. HPV-16 E5 down-regulates expression of surface HLA class I and reduces recognition by CD8 T cells. , 2010, Virology.
[52] K. Ang,et al. Human papillomavirus and survival of patients with oropharyngeal cancer. , 2010, The New England journal of medicine.
[53] M. Tan,et al. Oropharynx cancer (OPC) in TAX 324: Human papillomavirus (HPV) and survival. , 2010 .
[54] S. H. van der Burg,et al. Vaccination against HPV-16 oncoproteins for vulvar intraepithelial neoplasia. , 2009, The New England journal of medicine.
[55] Nancy F. Hansen,et al. Accurate Whole Human Genome Sequencing using Reversible Terminator Chemistry , 2008, Nature.
[56] W. Alkema,et al. BioVenn – a web application for the comparison and visualization of biological lists using area-proportional Venn diagrams , 2008, BMC Genomics.
[57] William Stafford Noble,et al. Semi-supervised learning for peptide identification from shotgun proteomics datasets , 2007, Nature Methods.
[58] L. Mariani,et al. High-risk human papillomavirus affects prognosis in patients with surgically treated oropharyngeal squamous cell carcinoma. , 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[59] C. Arsov,et al. T cells specific for HPV16 E7 epitopes in patients with squamous cell carcinoma of the oropharynx , 2006, International journal of cancer.
[60] John Sidney,et al. Predicting population coverage of T-cell epitope-based diagnostics and vaccines , 2006, BMC Bioinformatics.
[61] M. Campo,et al. E5 protein of human papillomavirus type 16 selectively downregulates surface HLA class I , 2005, International journal of cancer.
[62] D. Sidransky,et al. Evidence for a causal association between human papillomavirus and a subset of head and neck cancers. , 2000, Journal of the National Cancer Institute.
[63] H. Rammensee,et al. SYFPEITHI: database for MHC ligands and peptide motifs , 1999, Immunogenetics.
[64] S. Syrjänen,et al. Morphological and immunohistochemical evidence suggesting human papillomavirus (HPV) involvement in oral squamous cell carcinogenesis. , 1983, International journal of oral surgery.