In vitro antioxidant and cytotoxic activity of ethanolic extract of Cinnamomum tamala (Tejpat) leaves

The present research was aimed to investigate in vitro antioxidant and cytotoxic effects of the ethanolic extract of the leaves of Cinnamomum tamala (Nees). The leaves of Cinnamomum tamala have shown good antioxidant and cytotoxic properties. Antioxidant activity of the extract was evaluated by using DPPH free radical scavenging assay and ascorbic acid used as a standard. The IC50 value of Cinnamomum tamala leaves was 13.55 μg/ml while the IC50 value of ascorbic acid was 5.35 μg/ml. Cytotoxic activity was evaluated by using brine shrimp lethality bioassay and vincristine sulphate used as a standard. In this assay, the LC50 value of the ethanolic extract of Cinnamomum tamala leaves was 17.82μg/ml whereas LC50 value of vincristine sulphate was 5.24μg/ml. Therefore, these results suggest that leaves extract of Cinnamomum tamala has antioxidant and cytotoxic activities.

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