Matrine Alleviates Sepsis-Induced Myocardial Injury by Inhibiting Ferroptosis and Apoptosis
暂无分享,去创建一个
Ling-ling Yu | Yun-Li Yu | Longlong Hu | Wenjun Zhang | Jun Luo | Yuhong Xiao | Yuhui Yang | Ye Yuan | Wenjun Zhang | Longlong Hu
[1] Shasha Xu,et al. LCZ696 protects against doxorubicin-induced cardiotoxicity by inhibiting ferroptosis via AKT/SIRT3/SOD2 signaling pathway activation. , 2022, International immunopharmacology.
[2] H. Ardehali,et al. The molecular and metabolic landscape of iron and ferroptosis in cardiovascular disease , 2022, Nature Reviews Cardiology.
[3] Lingjiang Zhu,et al. Semaphorin 5A suppresses ferroptosis through activation of PI3K-AKT-mTOR signaling in rheumatoid arthritis , 2022, Cell Death & Disease.
[4] Hui-Hua Li,et al. Time Series Transcriptomic Analysis by RNA Sequencing Reveals a Key Role of PI3K in Sepsis-Induced Myocardial Injury in Mice , 2022, Frontiers in Physiology.
[5] P. Yu,et al. Puerarin protects against sepsis-induced myocardial injury through AMPK-mediated ferroptosis signaling , 2022, Aging.
[6] Guoyong Zhang,et al. Targeting Mitochondrial ROS-Mediated Ferroptosis by Quercetin Alleviates High-Fat Diet-Induced Hepatic Lipotoxicity , 2022, Frontiers in Pharmacology.
[7] Xiaomei Yang,et al. Propofol Protects Myocardium From Ischemia/Reperfusion Injury by Inhibiting Ferroptosis Through the AKT/p53 Signaling Pathway , 2022, Frontiers in Pharmacology.
[8] Zeqing Huang,et al. Bupivacaine modulates the apoptosis and ferroptosis in bladder cancer via phosphatidylinositol 3-kinase (PI3K)/AKT pathway , 2022, Bioengineered.
[9] Dan Xu,et al. Lapatinib induces mitochondrial dysfunction to enhance oxidative stress and ferroptosis in doxorubicin-induced cardiomyocytes via inhibition of PI3K/AKT signaling pathway , 2021, Bioengineered.
[10] Yuetang Wang,et al. Metformin alleviates the calcification of aortic valve interstitial cells through activating the PI3K/AKT pathway in an AMPK dependent way , 2021, Molecular Medicine.
[11] He Huang,et al. Ferrostatin-1 alleviates lipopolysaccharide-induced cardiac dysfunction , 2021, Bioengineered.
[12] Jingqing Zhang,et al. Identification of potential therapeutic targets and mechanisms of COVID-19 through network analysis and screening of chemicals and herbal ingredients , 2021, Briefings Bioinform..
[13] Jianyuan Pan,et al. microRNA-193-3p attenuates myocardial injury of mice with sepsis via STAT3/HMGB1 axis , 2021, Journal of Translational Medicine.
[14] Wenqian Li,et al. Molecular pathways in sepsis-induced cardiomyocyte pyroptosis: novel finding on long non-coding RNA ZFAS1/miR-138-5p/SESN2 axis. , 2021, Immunology letters.
[15] Xin Wang,et al. The lncRNA XIST/miR-150-5p/c-Fos axis regulates sepsis-induced myocardial injury via TXNIP-modulated pyroptosis , 2021, Laboratory Investigation.
[16] Jun-bo Zheng,et al. Narciclasine attenuates sepsis-induced myocardial injury by modulating autophagy , 2021, Aging.
[17] Jing Zhu,et al. PINK1 contained in huMSC-derived exosomes prevents cardiomyocyte mitochondrial calcium overload in sepsis via recovery of mitochondrial Ca2+ efflux , 2021, Stem cell research & therapy.
[18] Dan Guo,et al. In vitro and in vivo anti-metastatic effect of the alkaliod matrine from Sophora flavecens on hepatocellular carcinoma and its mechanisms. , 2021, Phytomedicine : international journal of phytotherapy and phytopharmacology.
[19] E. Ahmed,et al. Kirenol Inhibits B[a]P-Induced Oxidative Stress and Apoptosis in Endothelial Cells via Modulation of the Nrf2 Signaling Pathway , 2021, Oxidative medicine and cellular longevity.
[20] Zhipeng Yao,et al. FAM134B-mediated endoplasmic reticulum autophagy protects against sepsis myocardial injury in mice , 2021, Aging.
[21] Jie Yang,et al. Mechanism of ferroptosis in hypertensive nephropathy , 2021, Translational andrology and urology.
[22] Jun Zhang,et al. Protective role of matrine in sepsis-associated cardiac dysfunction through regulating the lncRNA PTENP1/miR-106b-5p axis. , 2020, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
[23] C. Thompson,et al. Oncogenic activation of PI3K-AKT-mTOR signaling suppresses ferroptosis via SREBP-mediated lipogenesis , 2020, Proceedings of the National Academy of Sciences.
[24] A. Narayanankutty. Phytochemicals as PI3K/ Akt/ mTOR Inhibitors and Their Role in Breast Cancer Treatment. , 2020, Recent patents on anti-cancer drug discovery.
[25] Quanjun Yang,et al. Matrine: A Promising Natural Product With Various Pharmacological Activities , 2020, Frontiers in Pharmacology.
[26] G. Martin,et al. Effect of Vitamin C Infusion on Organ Failure and Biomarkers of Inflammation and Vascular Injury in Patients With Sepsis and Severe Acute Respiratory Failure: The CITRIS-ALI Randomized Clinical Trial. , 2019, JAMA.
[27] Q. Tang,et al. Matrine attenuates oxidative stress and cardiomyocyte apoptosis in doxorubicin-induced cardiotoxicity via maintaining AMPKα/UCP2 pathway , 2019, Acta pharmaceutica Sinica. B.
[28] Z. Peng,et al. Melatonin protects against sepsis‐induced cardiac dysfunction by regulating apoptosis and autophagy via activation of SIRT1 in mice , 2019, Life sciences.
[29] Donghai Chu,et al. Trichosanthis Pericarpium Aqueous Extract Protects H9c2 Cardiomyocytes from Hypoxia/Reoxygenation Injury by Regulating PI3K/Akt/NO Pathway , 2018, Molecules.
[30] Xinzhong Dong,et al. Matrine inhibits itching by lowering the activity of calcium channel , 2018, Scientific Reports.
[31] Yu-Dong Cai,et al. Prediction and analysis of essential genes using the enrichments of gene ontology and KEGG pathways , 2017, PloS one.
[32] Jiaxiang Guo,et al. Matrine inhibits bladder cancer cell growth and invasion in vitro through PI3K/AKT signaling pathway: An experimental study. , 2017, Asian Pacific journal of tropical medicine.
[33] Honggang Hu,et al. The Matrine Derivate MASM Prolongs Survival, Attenuates Inflammation, and Reduces Organ Injury in Murine Established Lethal Sepsis. , 2016, The Journal of infectious diseases.
[34] N. van Bruggen,et al. RIPK3 deficiency or catalytically inactive RIPK1 provides greater benefit than MLKL deficiency in mouse models of inflammation and tissue injury , 2016, Cell Death and Differentiation.
[35] T. Luo,et al. Matrine compromises mouse sperm functions by a [Ca(2+)]i-related mechanism. , 2016, Reproductive toxicology.
[36] Chian-Jiun Liou,et al. Matrine Attenuates COX-2 and ICAM-1 Expressions in Human Lung Epithelial Cells and Prevents Acute Lung Injury in LPS-Induced Mice , 2016, Mediators of inflammation.
[37] Gang Fu,et al. PubChem Substance and Compound databases , 2015, Nucleic Acids Res..
[38] Jie Wang,et al. Matrine attenuates focal cerebral ischemic injury by improving antioxidant activity and inhibiting apoptosis in mice , 2015, International journal of molecular medicine.
[39] Ming-hui Li,et al. Developmental toxicity and neurotoxicity of two matrine-type alkaloids, matrine and sophocarpine, in zebrafish (Danio rerio) embryos/larvae. , 2014, Reproductive toxicology.
[40] Li-Chen Chen,et al. Matrine attenuates allergic airway inflammation and eosinophil infiltration by suppressing eotaxin and Th2 cytokine production in asthmatic mice. , 2014, Journal of ethnopharmacology.
[41] M. R. Lamprecht,et al. Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death , 2012, Cell.
[42] R. Naumann. The role of the phosphatidylinositol 3-kinase (PI3K) pathway in the development and treatment of uterine cancer. , 2011, Gynecologic oncology.
[43] Xueying Sun,et al. Matrine attenuates endotoxin-induced acute liver injury after hepatic ischemia/reperfusion in rats , 2011, Surgery Today.
[44] L. Cantley,et al. PI3K pathway alterations in cancer: variations on a theme , 2008, Oncogene.
[45] T. Hei,et al. Combined treatment with EGFR inhibitors and arsenite upregulated apoptosis in human EGFR-positive melanomas: a role of suppression of the PI3K-AKT pathway , 2005, Oncogene.
[46] OUP accepted manuscript , 2022, Briefings In Bioinformatics.
[47] Brad T. Sherman,et al. DAVID: Database for Annotation, Visualization, and Integrated Discovery , 2003, Genome Biology.