Highly potent soluble amyloid-β seeds in human Alzheimer brain but not cerebrospinal fluid.
暂无分享,去创建一个
J. Wiltfang | M. Staufenbiel | H. Zetterberg | C. Kaminski | M. Jucker | E. Portelius | W. Maetzler | P. Spitzer | G. K. Kaminski Schierle | K. Keyvani | S. Kaeser | L. Maia | D. Pinotsi | D. Winkler | Sarah K Fritschi | Franziska Langer | Sarah K. Fritschi
[1] E. Scarpini,et al. Detection of misfolded Aβ oligomers for sensitive biochemical diagnosis of Alzheimer's disease. , 2014, Cell reports.
[2] Clemens F. Kaminski,et al. Direct Observation of Heterogeneous Amyloid Fibril Growth Kinetics via Two-Color Super-Resolution Microscopy , 2013, Nano letters.
[3] Mathias Jucker,et al. Self-propagation of pathogenic protein aggregates in neurodegenerative diseases , 2013, Nature.
[4] M. Staufenbiel,et al. Changes in Amyloid-β and Tau in the Cerebrospinal Fluid of Transgenic Mice Overexpressing Amyloid Precursor Protein , 2013, Science Translational Medicine.
[5] K. Blennow,et al. Evaluating Amyloid-β Oligomers in Cerebrospinal Fluid as a Biomarker for Alzheimer’s Disease , 2013, PloS one.
[6] David A Bennett,et al. Brain amyloid-β oligomers in ageing and Alzheimer's disease. , 2013, Brain : a journal of neurology.
[7] C. Rowe,et al. Amyloid β deposition, neurodegeneration, and cognitive decline in sporadic Alzheimer's disease: a prospective cohort study , 2013, The Lancet Neurology.
[8] R. Sperling,et al. New ELISAs with high specificity for soluble oligomers of amyloid β-protein detect natural Aβ oligomers in human brain but not CSF , 2013, Alzheimer's & Dementia.
[9] D. Holtzman,et al. Amyloid‐beta oligomerization in Alzheimer dementia versus high‐pathology controls , 2013, Annals of neurology.
[10] Henrik Zetterberg,et al. Fluid biomarkers in Alzheimer disease. , 2012, Cold Spring Harbor perspectives in medicine.
[11] Nick C Fox,et al. Clinical and biomarker changes in dominantly inherited Alzheimer's disease. , 2012, The New England journal of medicine.
[12] L. Mucke,et al. Neurotoxicity of amyloid β-protein: synaptic and network dysfunction. , 2012, Cold Spring Harbor perspectives in medicine.
[13] Nick C Fox,et al. Brain imaging in Alzheimer disease. , 2012, Cold Spring Harbor perspectives in medicine.
[14] Mathias Jucker,et al. The Amyloid State of Proteins in Human Diseases , 2012, Cell.
[15] M. Staufenbiel,et al. Soluble Aβ Seeds Are Potent Inducers of Cerebral β-Amyloid Deposition , 2011, The Journal of Neuroscience.
[16] C. Dobson,et al. In situ measurements of the formation and morphology of intracellular β-amyloid fibrils by super-resolution fluorescence imaging. , 2011, Journal of the American Chemical Society.
[17] J. Morris,et al. Alzheimer’s Disease: The Challenge of the Second Century , 2011, Science Translational Medicine.
[18] Frank Baumann,et al. Peripherally Applied Aβ-Containing Inoculates Induce Cerebral β-Amyloidosis , 2010, Science.
[19] D. Selkoe,et al. The presence of sodium dodecyl sulphate-stable Abeta dimers is strongly associated with Alzheimer-type dementia. , 2010, Brain : a journal of neurology.
[20] K. Blennow,et al. Mass spectrometric characterization of brain amyloid beta isoform signatures in familial and sporadic Alzheimer’s disease , 2010, Acta Neuropathologica.
[21] K. Imahori,et al. Isolation and Characterization of Patient-derived, Toxic, High Mass Amyloid β-Protein (Aβ) Assembly from Alzheimer Disease Brains* , 2009, The Journal of Biological Chemistry.
[22] C. Glabe,et al. Soluble fibrillar oligomer levels are elevated in Alzheimer's disease brain and correlate with cognitive dysfunction , 2009, Neurobiology of Disease.
[23] K. Blennow,et al. Prediction and longitudinal study of CSF biomarkers in mild cognitive impairment , 2009, Neurobiology of Aging.
[24] Henrik Zetterberg,et al. Characterization of amyloid beta peptides in cerebrospinal fluid by an automated immunoprecipitation procedure followed by mass spectrometry. , 2007, Journal of proteome research.
[25] A. Giese,et al. Cell-free formation of misfolded prion protein with authentic prion infectivity , 2006, Proceedings of the National Academy of Sciences.
[26] D. Walsh,et al. Exogenous Induction of Cerebral ß-Amyloidogenesis Is Governed by Agent and Host , 2006, Science.
[27] M. Staufenbiel,et al. Amyloid-Associated Neuron Loss and Gliogenesis in the Neocortex of Amyloid Precursor Protein Transgenic Mice , 2002, The Journal of Neuroscience.
[28] A. Roher,et al. Evidence for Seeding of β-Amyloid by Intracerebral Infusion of Alzheimer Brain Extracts in β-Amyloid Precursor Protein-Transgenic Mice , 2000, The Journal of Neuroscience.
[29] B. Sommer,et al. Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[30] T. Wisniewski,et al. Cerebrospinal fluid inhibits Alzheimer β‐amyloid fibril formation in vitro , 1993, Annals of neurology.
[31] D. Teplow,et al. Cerebrospinal Fluid from Alzheimer's disease patients promotes amyloid beta-protein oligomerization. , 2010, Journal of Alzheimer's disease : JAD.
[32] J. Hardy,et al. The Amyloid Hypothesis of Alzheimer ’ s Disease : Progress and Problems on the Road to Therapeutics , 2009 .
[33] D. Teplow. Preparation of amyloid beta-protein for structural and functional studies. , 2006, Methods in enzymology.
[34] D. Teplow. Preparation of amyloid β-protein for structural and functional studies , 2006 .
[35] P. Scheltens,et al. Effects of processing and storage conditions on amyloid beta (1-42) and tau concentrations in cerebrospinal fluid: implications for use in clinical practice. , 2005, Clinical chemistry.
[36] A. Roher,et al. Evidence for seeding of beta -amyloid by intracerebral infusion of Alzheimer brain extracts in beta -amyloid precursor protein-transgenic mice. , 2000, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[37] P. Lansbury,et al. Models of amyloid seeding in Alzheimer's disease and scrapie: mechanistic truths and physiological consequences of the time-dependent solubility of amyloid proteins. , 1997, Annual review of biochemistry.