Nanoparticle‐mediated photothermal therapy: A comparative study of heating for different particle types

Near‐infrared (NIR) absorbing plasmonic nanoparticles enhance photothermal therapy of tumors. In this procedure, systemically delivered gold nanoparticles preferentially accumulate at the tumor site and when irradiated using laser light, produce localized heat sufficient to damage tumor cells. Gold nanoshells and nanorods have been widely studied for this purpose, and while both exhibit strong NIR absorption, their overall absorption and scattering properties differ widely due to their geometry. In this paper, we compared the photothermal response of both nanoparticle types including the heat generation and photothermal efficiency.

[1]  Glenn P. Goodrich,et al.  Photothermal Efficiencies of Nanoshells and Nanorods for Clinical Therapeutic Applications , 2009 .

[2]  L. Brannon-Peppas,et al.  Nanoparticle and targeted systems for cancer therapy. , 2004, Advanced drug delivery reviews.

[3]  T. Niidome,et al.  Gold Nanorod-sensitized Cell Death: Microscopic Observation of Single Living Cells Irradiated by Pulsed Near-infrared Laser Light in the Presence of Gold Nanorods , 2006 .

[4]  Thomas Kelly,et al.  Synergistic enhancement of selective nanophotothermolysis with gold nanoclusters: Potential for cancer therapy , 2005, Lasers in surgery and medicine.

[5]  H. Maeda.  The enhanced permeability and retention (EPR) effect in tumor vasculature: the key role of tumor-selective macromolecular drug targeting. , 2001, Advances in enzyme regulation.

[6]  A. Laszlo.  The effects of hyperthermia on mammalian cell structure and function , 1992, Cell proliferation.

[7]  D. P. O'Neal,et al.  Photo-thermal tumor ablation in mice using near infrared-absorbing nanoparticles. , 2004, Cancer letters.

[8]  M. Hoepfner,et al.  Microscale Heat Transfer Transduced by Surface Plasmon Resonant Gold Nanoparticles. , 2007, The journal of physical chemistry. C, Nanomaterials and interfaces.

[9]  Erik C. Dreaden,et al.  Gold nanorod assisted near-infrared plasmonic photothermal therapy (PPTT) of squamous cell carcinoma in mice. , 2008, Cancer letters.

[10]  B. V. Bronk,et al.  Thermal Potentiation of Mammalian Cell Killing: Clues for Understanding and Potential for Tumor Therapy , 1976 .

[11]  J. D. Payne,et al.  Application of INAA to the build-up and clearance of gold nanoshells in clinical studies in mice , 2007 .

[12]  M. El-Sayed,et al.  Dependence of the enhanced optical scattering efficiency relative to that of absorption for gold metal nanorods on aspect ratio, size, end-cap shape, and medium refractive index. , 2005, The journal of physical chemistry. B.

[13]  Michael J Sailor,et al.  Computationally guided photothermal tumor therapy using long-circulating gold nanorod antennas. , 2009, Cancer research.

[14]  Xunbin Wei,et al.  Selective cell targeting with light-absorbing microparticles and nanoparticles. , 2003, Biophysical journal.

[15]  Reginald Birngruber,et al.  On the possibility of high-precision photothermal microeffects and the measurement of fast thermal denaturation of proteins , 1999 .

[16]  H. Maeda,et al.  Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review. , 2000, Journal of controlled release : official journal of the Controlled Release Society.

[17]  H. Maeda,et al.  Exploiting the enhanced permeability and retention effect for tumor targeting. , 2006, Drug discovery today.

[18]  J. Bischof,et al.  In Situ Thermal Denaturation of Proteins in Dunning AT-1 Prostate Cancer Cells: Implication for Hyperthermic Cell Injury , 2004, Annals of Biomedical Engineering.

[19]  D. Lynch,et al.  Optical properties of metals. , 1981, Applied optics.

[20]  Kelly L. Gill-Sharp,et al.  In Vivo Detection of Gold Nanoshells in Tumors Using Diffuse Optical Spectroscopy , 2007, IEEE Journal of Selected Topics in Quantum Electronics.

[21]  Xiaohua Huang,et al.  Selective laser photo-thermal therapy of epithelial carcinoma using anti-EGFR antibody conjugated gold nanoparticles. , 2006, Cancer letters.

[22]  R. Stafford,et al.  Nanoshell-mediated near-infrared thermal therapy of tumors under magnetic resonance guidance , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[23]  Hui Zhang,et al.  Immuno gold nanocages with tailored optical properties for targeted photothermal destruction of cancer cells. , 2007, Nano letters.

[24]  A. Govorov,et al.  Experimental and theoretical studies of light-to-heat conversion and collective heating effects in metal nanoparticle solutions. , 2009, Nano letters.

[25]  K. Sokolov,et al.  Two-photon luminescence imaging of cancer cells using molecularly targeted gold nanorods. , 2007, Nano letters.

[26]  P. Jain,et al.  Calculated absorption and scattering properties of gold nanoparticles of different size, shape, and composition: applications in biological imaging and biomedicine. , 2006, The journal of physical chemistry. B.

[27]  J. Karp,et al.  Nanocarriers as an Emerging Platform for Cancer Therapy , 2022 .

[28]  B. Draine,et al.  Discrete-Dipole Approximation For Scattering Calculations , 1994 .

[29]  H. J. van Staveren,et al.  Light scattering in Intralipid-10% in the wavelength range of 400-1100 nm. , 1991, Applied optics.

[30]  Younan Xia,et al.  Gold nanostructures: engineering their plasmonic properties for biomedical applications. , 2006, Chemical Society reviews.

[31]  Naomi J. Halas,et al.  Nanoengineering of optical resonances , 1998 .

[32]  N. Félidj,et al.  Discrete dipole approximation for ultraviolet-visible extinction spectra simulation of silver and gold colloids , 1999 .

[33]  Prashant K. Jain,et al.  Plasmonic coupling in noble metal nanostructures , 2010 .

[34]  J. Lepock,et al.  Cellular effects of hyperthermia: relevance to the minimum dose for thermal damage , 2003, International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group.

[35]  R. W. Christy,et al.  Optical Constants of the Noble Metals , 1972 .

[36]  M. Pileni,et al.  Optical properties of gold nanorods: DDA simulations supported by experiments. , 2005, The journal of physical chemistry. B.

[37]  J. West,et al.  Near-infrared resonant nanoshells for combined optical imaging and photothermal cancer therapy. , 2007, Nano letters.

[38]  Srirang Manohar,et al.  Discrete Dipole Approximation simulations of gold nanorod optical properties:choice of input parameters and comparison with experiment , 2009 .

[39]  K. Henle,et al.  Heat fractionation and thermotolerance: a review. , 1978, Cancer research.

[40]  Jianfang Wang,et al.  Understanding the photothermal conversion efficiency of gold nanocrystals. , 2010, Small.

[41]  E. D. Palik.  Handbook of optical constants (A) , 1984 .

[42]  Christian Mätzler,et al.  MATLAB Functions for Mie Scattering and Absorption , 2002 .

[43]  J. West,et al.  Immunotargeted nanoshells for integrated cancer imaging and therapy. , 2005, Nano letters.

[44]  C. Yeh,et al.  Comparative efficiencies of photothermal destruction of malignant cells using antibody-coated silica@Au nanoshells, hollow Au/Ag nanospheres and Au nanorods , 2009, Nanotechnology.

[45]  Catherine J. Murphy,et al.  Wet Chemical Synthesis of High Aspect Ratio Cylindrical Gold Nanorods , 2001 .

[46]  Ji-Xin Cheng,et al.  Gold Nanorods Mediate Tumor Cell Death by Compromising Membrane Integrity , 2007, Advanced materials.

[47]  Prashant K. Jain,et al.  Plasmonic photothermal therapy (PPTT) using gold nanoparticles , 2008, Lasers in Medical Science.

[48]  I. Malitson.  Interspecimen Comparison of the Refractive Index of Fused Silica , 1965 .