Apert's acrocephalosyndactylism.

In 1906 Apert (2) first called attention to the syndrome of coronal suture synostosis (acrocephaly) and syndactylism. Combining the two conditions which were so frequently associated, Apert suggested the term acrocephalosyndactylism. Later reviews have appeared in the medical literature but none in American radiological journals. It is our purpose to report a case and to discuss the syndrome. Case Report J. G., a Negro female, was born at Michael Reese Hospital, weighing 8 pounds, the product of a thirty-nine weeks normal gestation. Neither parent gave any history of significant familial disease or malformation. At birth the abnormal findings were confined to the skull and extremities. The skull was shortened in the anteroposterior diameter, with a lengthened vertical diameter, the anterior fontanel was open but descended unusually far frontally, and there was a highly arched and narrowed palate with a cartilaginous cleft on the left side. Bilaterally symmetrical syndactylism of the second to the fifth fi...