Classic diseases revisited The irritable bowel syndrome

Irritable bowel syndrome is a common disorder varying in severity from trivial to incapacitating. The pathophysiology and epidemiology are gradually being unravelled and it is now becoming apparent just how poor the quality oflife ofsome ofthese patients can be. It is no longer acceptable practice to diagnose the condition and discharge the patient on a high fibre diet, particularly as the latter can often make the situation worse. Although hard to treat, worthwhile responses can be achieved by careful targeting of therapy to the many different facets of the disorder.

[1]  R. Clouse.  Antidepressants for functional gastrointestinal syndromes , 1994, Digestive Diseases and Sciences.

[2]  P. Whorwell,et al.  High Prevalence of Irritable Bowel Syndrome in Patients Attending Urological Outpatient Departments , 1997, Digestive Diseases and Sciences.

[3]  P. Whorwell,et al.  Visceral sensation and emotion: a study using hypnosis , 1995, Gut.

[4]  P. Whorwell,et al.  Syuptomatology, quality of life and economic features of irritable bowel syndrome—the effect of hypnotherapy , 1996, Alimentary pharmacology & therapeutics.

[5]  P. Whorwell,et al.  Acute diarrhoea induces rectal sensitivity in women but not men. , 1995, Gut.

[6]  I. Olubuyide,et al.  A study of irritable bowel syndrome diagnosed by manning criteria in an African population , 1995, Digestive diseases and sciences.

[7]  P. Whorwell,et al.  Bran and irritable bowel syndrome: time for reappraisal , 1994, The Lancet.

[8]  J. Misiewicz,et al.  Cephalic phase of colonic pressure response to food. , 1993, Gut.

[9]  P. Whorwell,et al.  Abdominal distension in irritable bowel syndrome : the patient's perception , 1992 .

[10]  P. Whorwell,et al.  More accurate diagnosis of irritable bowel syndrome by the use of 'non-colonic' symptomatology. , 1991, Gut.

[11]  D. Veale,et al.  Primary fibromyalgia and the irritable bowel syndrome: different expressions of a common pathogenetic process. , 1991, British journal of rheumatology.

[12]  P. Whorwell,et al.  Ranking of symptoms by patients with the irritable bowel syndrome. , 1989, BMJ.

[13]  E. Guthrie,et al.  Psychological treatments of the irritable bowel syndrome: a review. , 1989, Gut.

[14]  K. Klein.  Controlled treatment trials in the irritable bowel syndrome: a critique. , 1988, Gastroenterology.

[15]  P. Smith,et al.  Psychological factors in the irritable bowel syndrome. , 1988, Gut.

[16]  P. Whorwell,et al.  Severe sexual dysfunction in women with the irritable bowel syndrome: comparison with inflammatory bowel disease and duodenal ulceration. , 1987, British medical journal.

[17]  J. Lennard-jones,et al.  Treatment of functional abdominal pain by transcutaneous electrical nerve stimulation. , 1986, British medical journal.

[18]  W. Thompson.  Irritable bowel syndrome: prevalence, prognosis and consequences. , 1986, CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne.

[19]  W. Thayer,et al.  Diagnosis and management of irritable bowel syndrome. , 1984, Comprehensive therapy.

[20]  P. Whorwell,et al.  Symptoms of irritable bowel syndrome in ulcerative colitis in remission , 1983, Gut.

[21]  K. M. Holmes,et al.  Irritable bowel syndrome--a safe diagnosis? , 1982, British medical journal.

[22]  J. Hunter,et al.  FOOD INTOLERANCE: A MAJOR FACTOR IN THE PATHOGENESIS OF IRRITABLE BOWEL SYNDROME , 1982, The Lancet.

[23]  P. Openshaw,et al.  Towards positive diagnosis of the irritable bowel. , 1978, British medical journal.

[24]  S. Cohen,et al.  Effect of eating and gastrointestinal hormones on human colonic myoelectrical and motor activity. , 1978, Gastroenterology.

[25]  J. Bond,et al.  The role of intestinal gas in functional abdominal pain. , 1975, The New England journal of medicine.

[26]  J. Ritchie.  Pain from distension of the pelvic colon by inflating a balloon in the irritable colon syndrome 1 , 1973, Gut.

[27]  A. Read,et al.  Effect of cholecystokinin on colonic motility and symptoms in patients with the irritable-bowel syndrome. , 1973, Lancet.

[28]  Jones Fa,et al.  Motility of the pelvic colon: Part IV Abdominal pain associated with colonic hypermotility after meals , 1965 .

[29]  D. Kerr.  IRRITABLE COLON. , 1963, British medical journal.

[30]  J. Farrar,et al.  Intraluminal small intestinal pressures in normal patients and in patients with functional gastrointestinal disorders. , 1962, Gastroenterology.