Uptake of fluorescein isothiocyanate-labelled dextran into the CSF after intranasal and intravenous administration to rats.

[1]  F. Merkus,et al.  Uptake of estradiol or progesterone into the CSF following intranasal and intravenous delivery in rats. , 2004, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[2]  P. Merkus,et al.  Uptake of Melatonin into the Cerebrospinal Fluid After Nasal and Intravenous Delivery: Studies in Rats and Comparison with a Human Study , 2004, Pharmaceutical Research.

[3]  E. Bechgaard,et al.  The potential of nasal application for delivery to the central brain-a microdialysis study of fluorescein in rats. , 2004, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

[4]  L. Dittert,et al.  Enhancement of the Systemic and CNS Specific Delivery of L-Dopa by the Nasal Administration of Its Water Soluble Prodrugs , 2000, Pharmaceutical Research.

[5]  E. Brittebo,et al.  Transfer of Dopamine in the Olfactory Pathway Following Nasal Administration in Mice , 2000, Pharmaceutical Research.

[6]  Wei Yang Lu,et al.  Profiles of methotrexate in blood and CSF following intranasal and intravenous administration to rats. , 2003, International journal of pharmaceutics.

[7]  P. Merkus,et al.  Hydroxocobalamin Uptake into the Cerebrospinal Fluid after Nasal and Intravenous Delivery in Rats and Humans , 2003, Journal of drug targeting.

[8]  H. Guchelaar,et al.  Direct access of drugs to the human brain after intranasal drug administration? , 2003, Neurology.

[9]  Jan Born,et al.  Sniffing neuropeptides: a transnasal approach to the human brain , 2002, Nature Neuroscience.

[10]  F. Merkus,et al.  Serial cerebrospinal fluid sampling in a rat model to study drug uptake from the nasal cavity , 2002, Journal of Neuroscience Methods.

[11]  B. Jansson,et al.  Visualization of In Vivo Olfactory Uptake and Transfer Using Fluorescein Dextran , 2002, Journal of drug targeting.

[12]  F. Merkus,et al.  Uptake of hydrocortisone into the cerebrospinal fluid of rats: comparison of intranasal and intravenous administration in the same animal , 2002 .

[13]  L. Illum.  Transport of drugs from the nasal cavity to the central nervous system. , 2000, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

[14]  E. Björk,et al.  Nasal absorption of (S)-UH-301 and its transport into the cerebrospinal fluid of rats. , 2000, International journal of pharmaceutics.

[15]  M. Saneyoshi,et al.  Direct transport of 2',3'-didehydro-3'-deoxythymidine (D4T) and its ester derivatives to the cerebrospinal fluid via the nasal mucous membrane in rats. , 1998, Biological & pharmaceutical bulletin.

[16]  U. Kompella,et al.  Nasal route for direct delivery of solutes to the central nervous system: fact or fiction? , 1998, Journal of drug targeting.

[17]  M. Hussain,et al.  Intranasal absorption of the platelet glycoprotein IIb/IIIa receptor antagonist, DMP 755, and the effect of anesthesia on nasal bioavailability. , 1997, Journal of pharmaceutical sciences.

[18]  K. Chou,et al.  Distribution of antihistamines into the CSF following intranasal delivery. , 1997, Biopharmaceutics & drug disposition.

[19]  L. Illum,et al.  Investigation of the effect of anaesthesia on nasal absorption of insulin in rats , 1997 .

[20]  J. Born,et al.  A nose-brain pathway for psychotropic peptides: evidence from a brain evoked potential study with cholecystokinin , 1996, Psychoneuroendocrinology.

[21]  S. Yamashita,et al.  Direct Drug Transport from the Rat Nasal Cavity to the Cerebrospinal Fluid: the Relation to the Molecular Weight of Drugs , 1995, The Journal of pharmacy and pharmacology.

[22]  T. Seki,et al.  Nasal absorption of zidovudine and its transport to cerebrospinal fluid in rats. , 1994, Biological & pharmaceutical bulletin.

[23]  M. Sofroniew,et al.  Serum Proteins Bypass the Blood-Brain Fluid Barriers for Extracellular Entry to the Central Nervous System , 1993, Experimental Neurology.

[24]  M. Hashida,et al.  Transport of cephalexin to the cerebrospinal fluid directly from the nasal cavity , 1991, The Journal of pharmacy and pharmacology.

[25]  M. Hussain,et al.  Nasal administration of a cognition enhancer provides improved bioavailability but not enhanced brain delivery. , 1990, Journal of pharmaceutical sciences.

[26]  J. Tigges,et al.  Subarachnoid space of the CNS, nasal mucosa, and lymphatic system. , 1979, Archives of otolaryngology.

[27]  J. M. Yoffey.  Passage of Fluid and Other Substances Through the Nasal Mucosa , 1958, The Journal of Laryngology & Otology.