Novel drug-drug salts of enoxacin with enhanced antibacterial activity: Insights from solubility and lipid-water partition coefficient

[1]  Zhengzheng Zhou,et al.  Two Polymorphic Cocrystals of Theophylline with Ferulic Acid , 2023, Crystal Growth & Design.

[2]  Yang Lu,et al.  The enhanced pH-dependent solubility behavior of three novel lamotrigine-acid salts , 2023, Journal of Molecular Liquids.

[3]  Yang Lu,et al.  Discovered Two Polymorphs and Two Solvates of Lamotrigine-Tolfenamic acid Salt: Thermal Behavior and Crystal Morphological Differences. , 2022, International journal of pharmaceutics.

[4]  Jianting Li,et al.  Structural landscape investigations on bendable plastic crystals of isonicotinamide polymorphs , 2022, Chinese Chemical Letters.

[5]  Z. Min,et al.  The antibacterial mechanism of perilla rosmarinic acid. , 2021, Biotechnology and applied biochemistry.

[6]  Ilma Nugrahani,et al.  Challenges and Progress in Nonsteroidal Anti-Inflammatory Drugs Co-Crystal Development , 2021, Molecules.

[7]  Dandan Huang,et al.  Phase solubility investigation and theoretical calculations on drug-drug cocrystals of carbamazepine with Emodin, Paeonol , 2021 .

[8]  Y. Azim,et al.  Challenges and opportunities of pharmaceutical cocrystals: a focused review on non-steroidal anti-inflammatory drugs. , 2021, RSC medicinal chemistry.

[9]  T. Lu,et al.  Temozolomide–Hesperetin Drug–Drug Cocrystal with Optimized Performance in Stability, Dissolution, and Tabletability , 2021 .

[10]  M. K. Rana,et al.  Computer-aided discovery of bis-indole derivatives as multi-target drugs against cancer and bacterial infections: DFT, docking, virtual screening, and molecular dynamics studies , 2020 .

[11]  Sonali S. Bharate.  Recent developments in pharmaceutical salts: FDA approvals from 2015 to 2019. , 2020, Drug discovery today.

[12]  Yun-jie Zhang,et al.  Pharmaceutical salts/cocrystals of enoxacin with dicarboxylic acids: Enhancing in vitro antibacterial activity of enoxacin by improving the solubility and permeability. , 2020, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[13]  C. Iglesia,et al.  Therapeutic Suggestion in Postoperative Pain Control: A Randomized Controlled Trial , 2020, Female pelvic medicine & reconstructive surgery.

[14]  Yan-Tuan Li,et al.  A crystalline solid adduct of sulfathiazole–amantadine: the first dual-drug molecular salt containing both antiviral and antibacterial ingredients , 2020, CrystEngComm.

[15]  N. Asfandiyarova,et al.  [The use of nonsteroidal anti - inflammatory drugs in polymorbid pathology]. , 2020, Terapevticheskii arkhiv.

[16]  B. Bhattacharya,et al.  Screening, crystal structures and solubility studies of a series of multidrug salt hydrates and cocrystals of fenamic acids with trimethoprim and sulfamethazine , 2020 .

[17]  Hailu Zhang,et al.  Crystal Structures, Dissolution and Pharmacokinetic Study on a Novel Phosphodiesterase-4 Inhibitor Chlorbipram Cocrystals. , 2019, International journal of pharmaceutics.

[18]  H. Tong,et al.  Structure determination and in vitro/vivo study on carbamazepine-naringenin (1:1) cocrystal , 2019 .

[19]  H. Tong,et al.  X-ray Diffraction and Theoretical Calculation-Supported Formation of Polymorphic Cocrystals Discovered Through Thermal Methods: A Case Study. , 2019, Journal of pharmaceutical sciences.

[20]  J. Gong,et al.  Drug–drug salts of mefenamic acid\tolfenamic acid and piperazine to improve physicochemical properties for potential veterinary use , 2019, CrystEngComm.

[21]  Panos Macheras,et al.  The Biopharmaceutics Classification System (BCS) and the Biopharmaceutics Drug Disposition Classification System (BDDCS): Beyond guidelines. , 2019, International journal of pharmaceutics.

[22]  Ana R. Jesus,et al.  Enhancement of water solubility of poorly water‐soluble drugs by new biocompatible N‐acetyl amino acid N‐alkyl cholinium‐based ionic liquids , 2019, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[23]  N. Jetté,et al.  Preoperative predictors of poor acute postoperative pain control: a systematic review and meta-analysis , 2019, BMJ Open.

[24]  Changquan Calvin Sun,et al.  Spherical Cocrystallization—An Enabling Technology for the Development of High Dose Direct Compression Tablets of Poorly Soluble Drugs , 2019, Crystal Growth & Design.

[25]  A. Mondal,et al.  Multidrug salt forms of norfloxacin with non-steroidal anti-inflammatory drugs: solubility and membrane permeability studies , 2018 .

[26]  Ranjit Thakuria,et al.  Drug‑Drug and Drug‑Nutraceutical Cocrystal/Salt as Alternative Medicine for Combination Therapy: A Crystal Engineering Approach , 2018 .

[27]  Naír Rodríguez-Hornedo,et al.  Multidrug Cocrystal of Anticonvulsants: Influence of Strong Intermolecular Interactions on Physiochemical Properties. , 2017, Crystal growth & design.

[28]  Ranjit Thakuria,et al.  Crystal structure landscape of ethenzamide: a physicochemical property study , 2017 .

[29]  N. Abell,et al.  Click Quantitative Mass Spectrometry Identifies PIWIL3 as a Mechanistic Target of RNA Interference Activator Enoxacin in Cancer Cells. , 2017, Journal of the American Chemical Society.

[30]  G. Desiraju,et al.  A Drug-Drug Salt Hydrate of Norfloxacin and Sulfathiazole: Enhancement of in Vitro Biological Properties via Improved Physicochemical Properties. , 2016, Molecular pharmaceutics.

[31]  Ke Wang,et al.  Investigating the Influence of Polymers on Supersaturated Flufenamic Acid Cocrystal Solutions. , 2016, Molecular pharmaceutics.

[32]  Steven A. Ross,et al.  Engineering and manufacturing of pharmaceutical co-crystals: a review of solvent-free manufacturing technologies. , 2016, Chemical communications.

[33]  N. Rodríguez-Hornedo,et al.  How cocrystals of weakly basic drugs and acidic coformers might modulate solubility and stability. , 2016, Chemical communications.

[34]  R. Tan,et al.  Novel solid forms of oxaprozin: cocrystals and an extended release drug–drug salt of salbutamol , 2016 .

[35]  Dinesh Kumar,et al.  Multidrug co-crystals: towards the development of effective therapeutic hybrids. , 2016, Drug discovery today.

[36]  M. Zaworotko,et al.  Pharmaceutical cocrystals: along the path to improved medicines. , 2016, Chemical communications.

[37]  H. Sung,et al.  Identification of New Cocrystal Systems with Stoichiometric Diversity of Salicylic Acid Using Thermal Methods , 2016, Pharmaceutical Research.

[38]  K. Tam,et al.  pKa values in solubility determination using the Henderson-Hasselbalch equation , 2015 .

[39]  G. Desiraju,et al.  Tuning mechanical properties of pharmaceutical crystals with multicomponent crystals: voriconazole as a case study. , 2015, Molecular pharmaceutics.

[40]  G. Sheldrick.  SHELXT – Integrated space-group and crystal-structure determination , 2015, Acta crystallographica. Section A, Foundations and advances.

[41]  A. P. Voronin,et al.  Pharmaceutical cocrystals of diflunisal and diclofenac with theophylline. , 2014, Molecular pharmaceutics.

[42]  R. Tan,et al.  Cocrystallization with flufenamic acid: comparison of physicochemical properties of two pharmaceutical cocrystals , 2014 .

[43]  C. Cellini,et al.  Postoperative Pain Control , 2013, Clinics in Colon and Rectal Surgery.

[44]  A. Healy,et al.  Formation and physicochemical properties of crystalline and amorphous salts with different stoichiometries formed between ciprofloxacin and succinic acid. , 2013, Molecular pharmaceutics.

[45]  A. Choudhury,et al.  Structural Landscape of Pure Enrofloxacin and Its Novel Salts: Enhanced Solubility for Better Pharmaceutical Applicability , 2013 .

[46]  N. Rodríguez-Hornedo,et al.  Tailoring aqueous solubility of a highly soluble compound via cocrystallization: effect of coformer ionization, pHmax and solute–solvent interactions , 2012 .

[47]  Gargi Mukherjee,et al.  Polymorphs, Salts, and Cocrystals: What’s in a Name? , 2012 .

[48]  J. Comer,et al.  Study of pH-dependent solubility of organic bases. Revisit of Henderson-Hasselbalch relationship. , 2010, Analytica chimica acta.

[49]  Zhaoxin Lu,et al.  Study on the antibiotic activity of microcapsule curcumin against foodborne pathogens. , 2009, International journal of food microbiology.

[50]  Pui Shan Chow,et al.  Trimorphs of a pharmaceutical cocrystal involving two active pharmaceutical ingredients: potential relevance to combination drugs , 2009 .

[51]  N. Sultana,et al.  Synthesis, Characterization, Antibacterial and Anti-Inflammatory Activities of Enoxacin Metal Complexes , 2009, Bioinorganic chemistry and applications.

[52]  Naír Rodríguez-Hornedo,et al.  Understanding and Predicting the Effect of Cocrystal Components and pH on Cocrystal Solubility , 2009 .

[53]  Richard J. Gildea,et al.  OLEX2: a complete structure solution, refinement and analysis program , 2009 .

[54]  N. Rodríguez-Hornedo,et al.  Cocrystals and Salts of Gabapentin: pH Dependent Cocrystal Stability and Solubility , 2009 .

[55]  A. Avdeef.  Solubility of sparingly-soluble ionizable drugs. , 2007, Advanced drug delivery reviews.

[56]  Christer B Aakeröy,et al.  Cocrystal or salt: does it really matter? , 2007, Molecular pharmaceutics.

[57]  Dan Boström,et al.  Pharmaceutical Cocrystal and Salts of Norfloxacin , 2006 .

[58]  A. Berthod,et al.  Determination of liquid-liquid partition coefficients by separation methods. , 2004, Journal of chromatography. A.

[59]  Billie Yan Zhang Hiew,et al.  Adsorptive decontamination of diclofenac by three‐dimensional graphene‐based adsorbent: Response surface methodology, adsorption equilibrium, kinetic and thermodynamic studies , 2019, Environmental research.

[60]  U. Domańska,et al.  Study of pH-dependent drugs solubility in water , 2014 .

[61]  G. Borodi,et al.  Structural characterization of ambazone salt with niflumic acid , 2012 .

[62]  M. Wood.  Tissue Penetration and Clinical Efficacy of Enoxacin in Respiratory Tract Infections , 1989, Clinical pharmacokinetics.