Risk factors of chronic cough in China: a systematic review and meta-analysis

ABSTRACT Introduction Risk factors of chronic cough in China have not been systematically analyzed and we hypothesized that risk factors of chronic cough might have distinct characteristics in China. Hence, we performed this meta-analysis focusing on the potential risk factors of chronic cough in China. Areas covered This systematic review was performed to explore the risk factors of chronic cough in accordance with the PRISMA checklist. Seven databases were searched for published articles using predefined inclusion criteria. A total of 33 eligible articles were identified and included in this systematic review, and 28 studies were included in the meta-analysis. Expert commentary The study indicated that allergy, nasal/sinusitis diseases, family history of allergy, family history of chronic respiratory diseases, exposure to pollutants, passive smoking, and exposure to pets were risk factors for chronic cough in China. Although several potential risk factors (e.g.: sex and BMI) were not explore for the limited information in the included articles, this paper provides useful epidemiological information for managing chronic cough not only in China but around the world.

[1]  W. Song,et al.  Efficacy of non-sedating H1-receptor antihistamines in adults and adolescents with chronic cough: A systematic review , 2021, The World Allergy Organization journal.

[2]  B. Nordestgaard,et al.  Risk and impact of chronic cough in obese individuals from the general population , 2021, Thorax.

[3]  D. Kim,et al.  Differential features of chronic cough according to etiology and the simple decision tree for predicting causes , 2021, Scientific Reports.

[4]  A. Hansell,et al.  Ambient air pollution exposure and chronic bronchitis in the Lifelines cohort , 2021, Thorax.

[5]  B. Forsberg,et al.  Prevalence, progression and impact of chronic cough on employment in Northern Europe , 2020, European Respiratory Journal.

[6]  Y. Li,et al.  Association of pet-keeping in home with self-reported asthma and asthma-related symptoms in 11611 school children from China , 2020, The Journal of asthma : official journal of the Association for the Care of Asthma.

[7]  X. Zhang,et al.  Prevalence patterns of allergen sensitization by region, gender, age, and season among patients with allergic symptoms in mainland China: A four‐year multicenter study , 2020, Allergy.

[8]  N. Zhong,et al.  The Predicative Clinical Features Associated with Chronic Cough That Has a Single Underlying Cause , 2020, The Journal of Allergy and Clinical Immunology: In Practice.

[9]  A. Chang,et al.  Managing Chronic Cough as a Symptom in Children and Management Algorithms: CHEST Guideline and Expert Panel Report. , 2020, Chest.

[10]  B. Eskenazi,et al.  Household air pollution profiles associated with persistent childhood cough in urban Uganda. , 2020, Environment international.

[11]  B. Nordestgaard,et al.  Chronic cough in individuals with COPD: a population-based cohort study. , 2020, Chest.

[12]  Hehua Zhang,et al.  Ambient air pollution and daily hospital admissions for respiratory system–related diseases in a heavy polluted city in Northeast China , 2020, Environmental Science and Pollution Research.

[13]  P. Bogawski,et al.  Atmospheric exposure to the major Artemisia pollen allergen (Art v 1): Seasonality, impact of weather, and clinical implications. , 2020, The Science of the total environment.

[14]  S. Birring,et al.  ERS guidelines on the diagnosis and treatment of chronic cough in adults and children , 2019, European Respiratory Journal.

[15]  X. Bi,et al.  Traffic‐related air pollution induces non‐allergic eosinophilic airway inflammation and cough hypersensitivity in guinea‐pigs , 2019, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

[16]  Xiaoping Zhou,et al.  Artemisia pollen allergy in China: Component‐resolved diagnosis reveals allergic asthma patients have significant multiple allergen sensitization , 2018, Allergy.

[17]  Shu-nan Zhang,et al.  Clinical Practice Guidelines for Diagnosis and Management of Cough-Chinese Thoracic Society (CTS) Asthma Consortium. , 2018, Journal of thoracic disease.

[18]  L. Wang,et al.  [Prevalence and influencing factors of respiratory symptoms among people aged 40 years and above in China]. , 2018, Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi.

[19]  Yongjian Xu,et al.  Prevalence and risk factors of chronic obstructive pulmonary disease in China (the China Pulmonary Health [CPH] study): a national cross-sectional study , 2018, The Lancet.

[20]  S. Ernst,et al.  Respiratory and cardiovascular responses to walking down a traffic-polluted road compared with walking in a traffic-free area in participants aged 60 years and older with chronic lung or heart disease and age-matched healthy controls: a randomised, crossover study , 2017 .

[21]  T. H. Nguyen,et al.  Global, regional, and national deaths, prevalence, disability-adjusted life years, and years lived with disability for chronic obstructive pulmonary disease and asthma, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015 , 2017, The Lancet. Respiratory medicine.

[22]  B. Nordestgaard,et al.  Risk Factors for Chronic Cough Among 14,669 Individuals From the General Population , 2017, Chest.

[23]  M. Farrell,et al.  Central mechanisms of airway sensation and cough hypersensitivity. , 2017, Pulmonary pharmacology & therapeutics.

[24]  Y. Liu,et al.  Living near a Major Road in Beijing: Association with Lower Lung Function, Airway Acidification, and Chronic Cough , 2016, Chinese medical journal.

[25]  A. Baccarelli,et al.  Short-term exposure to high ambient air pollution increases airway inflammation and respiratory symptoms in chronic obstructive pulmonary disease patients in Beijing, China. , 2016, Environment international.

[26]  K. Lai,et al.  Effect of transient receptor potential vanilloid-1 on cough hypersensitivity induced by particulate matter 2.5. , 2016, Life sciences.

[27]  M. Mishima,et al.  Mechanical Stimulation by Postnasal Drip Evokes Cough , 2015, PloS one.

[28]  Ruizhi Zheng,et al.  Prevalence of suicide attempts among Chinese adolescents: A meta-analysis of cross-sectional studies. , 2015, Comprehensive psychiatry.

[29]  Xin-biao Guo,et al.  [Comparison of respiratory diseases and symptoms among school-age children in areas with different levels of air pollution]. , 2015, Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences.

[30]  S. Birring,et al.  The Impact of Chronic Cough: A Cross-Sectional European Survey , 2015, Lung.

[31]  A. Morice,et al.  The global epidemiology of chronic cough in adults: a systematic review and meta-analysis , 2015, European Respiratory Journal.

[32]  B. Undem,et al.  Mechanisms underlying the neuronal-based symptoms of allergy. , 2014, The Journal of allergy and clinical immunology.

[33]  T. Wong,et al.  Chronic effects of ambient air pollution on respiratory morbidities among Chinese children: a cross-sectional study in Hong Kong , 2014, BMC Public Health.

[34]  K. Chung,et al.  Chronic cough as a neuropathic disorder. , 2013, The Lancet. Respiratory medicine.

[35]  Wan-hui Ren,et al.  [Interactive effects of environmental tobacco smoke and pets ownership on respiratory diseases and symptoms in children]. , 2013, Zhonghua er ke za zhi = Chinese journal of pediatrics.

[36]  Wan-hui Ren,et al.  [The effects of breastfeeding on asthma and asthma related symptoms among children]. , 2012, Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine].

[37]  Kevin R. Smith,et al.  Cigarette smoke suppresses Bik to cause epithelial cell hyperplasia and mucous cell metaplasia. , 2011, American journal of respiratory and critical care medicine.

[38]  W. White.  Erratum to: Why I hate the index finger , 2011, Hand.

[39]  G. Guyatt,et al.  GRADE guidelines: 1. Introduction-GRADE evidence profiles and summary of findings tables. , 2011, Journal of clinical epidemiology.

[40]  Ken Takahashi,et al.  Air pollution and children's respiratory symptoms in six cities of Northern China. , 2010, Respiratory medicine.

[41]  P. Ran,et al.  Risk of COPD from exposure to biomass smoke: a metaanalysis. , 2010, Chest.

[42]  Peter G Gibson,et al.  CICADA: Cough in Children and Adults: Diagnosis and Assessment. Australian Cough Guidelines summary statement , 2010, The Medical journal of Australia.

[43]  G. Dong,et al.  Pets keeping in home, parental atopy, asthma, and asthma-related symptoms in 12,910 elementary school children from northeast China. , 2009, Indoor air.

[44]  H. Tsai,et al.  The Association of BMI and Sedentary Time with Respiratory Symptoms and Asthma in 5th Grade Schoolchildren in Kaohsiung, Taiwan , 2009, The Journal of asthma : official journal of the Association for the Care of Asthma.

[45]  T. Hoshuyama,et al.  Respiratory symptoms among residents of a heavy-industry province in China: prevalence and risk factors. , 2008, Respiratory medicine.

[46]  A Bush,et al.  Recommendations for the assessment and management of cough in children , 2007, Thorax.

[47]  T. Lam,et al.  Cross-sectional and prospective associations between passive smoking and respiratory symptoms at the workplace. , 2007, Annals of epidemiology.

[48]  Christian Schindler,et al.  Living near main streets and respiratory symptoms in adults: the Swiss Cohort Study on Air Pollution and Lung Diseases in Adults. , 2006, American journal of epidemiology.

[49]  I. Pavord,et al.  Recommendations for the management of cough in adults , 2006, Thorax.

[50]  P. Cagle,et al.  Interpreting the histopathology of chronic cough: a prospective, controlled, comparative study. , 2006, Chest.

[51]  Ru-chong Chen,et al.  [An epidemiologic study of cough in young college students in Guangzhou]. , 2006, Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi.

[52]  A. Nicholson,et al.  Nature of airway inflammation and remodeling in chronic cough. , 2005, The Journal of allergy and clinical immunology.

[53]  S. London,et al.  Childhood exposure to environmental tobacco smoke and chronic respiratory symptoms in non-smoking adults: The Singapore Chinese Health Study , 2005, Thorax.

[54]  G. Viegi,et al.  Rhinitis is an independent risk factor for developing cough apart from colds among adults , 2005, Allergy.

[55]  A. Morice,et al.  The diagnosis and management of chronic cough , 2004, European Respiratory Journal.

[56]  L. Korn,et al.  Factor analysis of household factors: are they associated with respiratory conditions in Chinese children? , 2004, International journal of epidemiology.

[57]  P. Gibson,et al.  Eosinophilic bronchitis: clinical manifestations and implications for treatment , 2002, Thorax.

[58]  D. Strachan,et al.  Respiratory symptoms and home environment in children: a national survey , 1999, Thorax.

[59]  B. Wüthrich,et al.  Respiratory health and long-term exposure to air pollutants in Swiss schoolchildren. SCARPOL Team. Swiss Study on Childhood Allergy and Respiratory Symptoms with Respect to Air Pollution, Climate and Pollen. , 1997, American journal of respiratory and critical care medicine.

[60]  K McCusker,et al.  Mechanisms of respiratory tissue injury from cigarette smoking. , 1992, The American journal of medicine.

[61]  Zhang Li-ju.  Environment-related factors associated with asthma and allergies among schoolchildren in two communities, Shanghai , 2014 .

[62]  Emine Argüder.  Diagnosis and Treatment of Chronic Cough , 2012 .

[63]  Huang Sheng-ron.  Influence of environmental factors on chronic cough in children , 2012 .

[64]  Lu Guo-lian.  Study on environmental risk factors for chronic cough in school children in urban,Shanghai , 2009 .

[65]  Y. Wang.  STUDY ON THE INFLUENCE OF AIR POLLUTION INSIDE DOOR OR OUTSIDE DOOR ON THE HEALTH OF THE SCHOOL CHILDREN , 2007 .

[66]  M. Pratter.  Chronic upper airway cough syndrome secondary to rhinosinus diseases (previously referred to as postnasal drip syndrome): ACCP evidence-based clinical practice guidelines. , 2006, Chest.

[67]  S. Tarlo.  Cough: occupational and environmental considerations: ACCP evidence-based clinical practice guidelines. , 2006, Chest.

[68]  D. Weldon.  Gastroesophageal reflux disease and sinusitis: their role in patients with chronic cough. , 2006, Allergy and asthma proceedings.

[69]  L. Boulet,et al.  Diagnosis and management of cough executive summary: ACCP evidence-based clinical practice guidelines. , 2006, Chest.

[70]  P. Dicpinigaitis.  Chronic cough due to asthma: ACCP evidence-based clinical practice guidelines. , 2006, Chest.

[71]  L. Strumylaitė,et al.  [Passive smoking and respiratory health of children]. , 2005, Medicina.