Variants of CCR5, which are permissive for HIV-1 infection, show distinct functional responses to CCL3, CCL4 and CCL5
暂无分享,去创建一个
M. Carrington | J. Turpin | M. Dean | O. Howard | H.-F. Dong | K. Wigmore
[1] C. Mackay. CCL3L1 dose and HIV-1 susceptibility. , 2005, Trends in molecular medicine.
[2] B. Rovin,et al. The Influence of CCL 3 L 1 Gene – Containing Segmental Duplications on HIV-1 / AIDS Susceptibility , 2009 .
[3] M. Oppermann,et al. Agonist-induced endocytosis of CC chemokine receptor 5 is clathrin dependent. , 2004, Molecular biology of the cell.
[4] M. Ng,et al. A novel CCR5 mutation selectively affects immunoreactivity and fusogenic property of the HIV co-receptor , 2004, AIDS.
[5] W. Modi,et al. Functional redundancy of the human CCL4 and CCL4L1 chemokine genes. , 2004, Biochemical and biophysical research communications.
[6] M. Oppermann,et al. pH‐Independent Endocytic Cycling of the Chemokine Receptor CCR5 , 2004, Traffic.
[7] G. Ahlenstiel,et al. CC-chemokine receptor 5 (CCR5) in hepatitis C--at the crossroads of the antiviral immune response? , 2004, The Journal of antimicrobial chemotherapy.
[8] D. Duffy,et al. CCR5-Delta32 mutation is strongly associated with primary sclerosing cholangitis. , 2004, Genes and immunity.
[9] B. Olde,et al. Molecular mapping of epitopes for interaction of HIV-1 as well as natural ligands with the chemokine receptors, CCR5 and CXCR4 , 2003, AIDS.
[10] Darrell R. Abernethy,et al. International Union of Pharmacology: Approaches to the Nomenclature of Voltage-Gated Ion Channels , 2003, Pharmacological Reviews.
[11] G. Dubyak,et al. Essential role for Ca2+ in regulation of IL-1beta secretion by P2X7 nucleotide receptor in monocytes, macrophages, and HEK-293 cells. , 2003, American journal of physiology. Cell physiology.
[12] Thomas P. Sakmar,et al. Analysis of the Mechanism by Which the Small-Molecule CCR5 Antagonists SCH-351125 and SCH-350581 Inhibit Human Immunodeficiency Virus Type 1 Entry , 2003, Journal of Virology.
[13] D. Taub,et al. MIP-1α and MIP-1β differentially mediate mucosal and systemic adaptive immunity , 2003 .
[14] M. Oppermann,et al. Analysis of Ligand-stimulated CC Chemokine Receptor 5 (CCR5) Phosphorylation in Intact Cells Using Phosphosite-specific Antibodies* , 2003, The Journal of Biological Chemistry.
[15] V. Robert-Hebmann,et al. Role of the intracellular domains of CXCR4 in SDF-1-mediated signaling. , 2003, Blood.
[16] D. Taub,et al. MIP-1alpha and MIP-1beta differentially mediate mucosal and systemic adaptive immunity. , 2003, Blood.
[17] M. Paterlini,et al. Structure modeling of the chemokine receptor CCR5: implications for ligand binding and selectivity. , 2002, Biophysical journal.
[18] M. Alizon,et al. Rescue of HIV-1 Receptor Function through Cooperation between Different Forms of the CCR5 Chemokine Receptor* , 2002, The Journal of Biological Chemistry.
[19] T. Hope,et al. Association of Chemokine-mediated Block to HIV Entry with Coreceptor Internalization* , 2002, The Journal of Biological Chemistry.
[20] J. Christensen,et al. The role of CC chemokine receptor 5 in antiviral immunity. , 2002, Blood.
[21] P. Strange,et al. Pathways for internalization and recycling of the chemokine receptor CCR5. , 2002, Blood.
[22] D. Weissman,et al. A Membrane-proximal Basic Domain and Cysteine Cluster in the C-terminal Tail of CCR5 Constitute a Bipartite Motif Critical for Cell Surface Expression* , 2001, The Journal of Biological Chemistry.
[23] Martin Oppermann,et al. Characterization of Sequence Determinants within the Carboxyl-terminal Domain of Chemokine Receptor CCR5 That Regulate Signaling and Receptor Internalization* , 2001, The Journal of Biological Chemistry.
[24] Dominique Schols,et al. Diverging binding capacities of natural LD78β isoforms of macrophage inflammatory protein‐1α to the CC chemokine receptors 1, 3 and 5 affect their anti‐HIV‐1 activity and chemotactic potencies for neutrophils and eosinophils , 2001, European journal of immunology.
[25] M. Oppermann,et al. Polymorphism of CC chemokine receptors CCR2 and CCR5 in Crohn's disease. , 2001, Immunology letters.
[26] M. Hammer,et al. Global survey of genetic variation in CCR5, RANTES, and MIP-1α: Impact on the epidemiology of the HIV-1 pandemic , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[27] Yuetsu Tanaka,et al. Naturally Occurring Deletional Mutation in the C-Terminal Cytoplasmic Tail of CCR5 Affects Surface Trafficking of CCR5 , 2001, Journal of Virology.
[28] B. Kwon,et al. The seventh transmembrane domain of cc chemokine receptor 5 is critical for MIP-1beta binding and receptor activation: role of MET 287. , 2001, Biochemical and biophysical research communications.
[29] R. Breyer,et al. Prostanoid receptors: subtypes and signaling. , 2001, Annual review of pharmacology and toxicology.
[30] R. Detels,et al. Chemokine RANTES promoter polymorphism affects risk of both HIV infection and disease progression in the Multicenter AIDS Cohort Study , 2000, AIDS.
[31] V. Rivera,et al. Aberrant T cell migration toward RANTES and MIP-1 alpha in patients with multiple sclerosis. Overexpression of chemokine receptor CCR5. , 2000, Brain : a journal of neurology.
[32] R. Doms,et al. Multiple nonfunctional alleles of CCR5 are frequent in various human populations. , 2000, Blood.
[33] K. Welsh,et al. Correspondence and requests for reprints should be addressed to Dr. Martin , 2022 .
[34] Atsushi Mizoguchi,et al. Mice with a Selective Deletion of the CC Chemokine Receptors 5 or 2 Are Protected from Dextran Sodium Sulfate-Mediated Colitis: Lack of CC Chemokine Receptor 5 Expression Results in a NK1.1+ Lymphocyte-Associated Th2-Type Immune Response in the Intestine1 , 2000, The Journal of Immunology.
[35] N. Maeda,et al. Contrasting effects of CCR5 and CCR2 deficiency in the pulmonary inflammatory response to influenza A virus. , 2000, The American journal of pathology.
[36] C. Broder,et al. N-Linked Glycosylation of CXCR4 Masks Coreceptor Function for CCR5-Dependent Human Immunodeficiency Virus Type 1 Isolates , 2000, Journal of Virology.
[37] K. Matsushima,et al. International union of pharmacology. XXII. Nomenclature for chemokine receptors. , 2000, Pharmacological reviews.
[38] A. Zlotnik,et al. Chemokines: a new classification system and their role in immunity. , 2000, Immunity.
[39] Finn Sellebjerg,et al. CCR5 Δ32, matrix metalloproteinase-9 and disease activity in multiple sclerosis , 2000, Journal of Neuroimmunology.
[40] J. Haines,et al. CC-chemokine receptor 5 polymorphism and age of onset in familial multiple sclerosis. Multiple Sclerosis Genetics Group. , 2000, Immunogenetics.
[41] C. V. Jensen,et al. CCR5 delta32, matrix metalloproteinase-9 and disease activity in multiple sclerosis. , 2000, Journal of neuroimmunology.
[42] J. Haines,et al. CC-chemokine receptor 5 polymorphism and age of onset in familial multiple sclerosis , 2000, Immunogenetics.
[43] J. Goedert,et al. Reduced risk of AIDS lymphoma in individuals heterozygous for the CCR5-delta32 mutation. , 1999, Cancer research.
[44] G Vassart,et al. Extracellular Cysteines of CCR5 Are Required for Chemokine Binding, but Dispensable for HIV-1 Coreceptor Activity* , 1999, The Journal of Biological Chemistry.
[45] A. Maynard,et al. Naturally Occurring CCR5 Extracellular and Transmembrane Domain Variants Affect HIV-1 Co-receptor and Ligand Binding Function* , 1999, The Journal of Biological Chemistry.
[46] J. Gómez-Reino,et al. Association of rheumatoid arthritis with a functional chemokine receptor, CCR5. , 1999, Arthritis and rheumatism.
[47] J. Goedert,et al. Chemokine and chemokine receptor gene variants and risk of non-Hodgkin's lymphoma in human immunodeficiency virus-1-infected individuals. , 1999, Blood.
[48] J. Sodroski,et al. CCR5 has an expanded ligand-binding repertoire and is the primary receptor used by MCP-2 on activated T cells. , 1998, Cellular immunology.
[49] H. Marquart,et al. CC chemokine receptor 5 polymorphism in rheumatoid arthritis. , 1998, The Journal of rheumatology.
[50] N. Tarasova,et al. Small molecule inhibitor of HIV‐1 cell fusion blocks chemokine receptor‐mediated function , 1998, Journal of leukocyte biology.
[51] D. Littman. Chemokine Receptors: Keys to AIDS Pathogenesis? , 1998, Cell.
[52] N. Taylor,et al. Macrophage inflammatory protein-1β induces migration and activation of human thymocytes , 1998 .
[53] John P. Moore,et al. Alanine Substitutions of Polar and Nonpolar Residues in the Amino-Terminal Domain of CCR5 Differently Impair Entry of Macrophage- and Dualtropic Isolates of Human Immunodeficiency Virus Type 1 , 1998, Journal of Virology.
[54] S. O’Brien,et al. C-C chemokines, pivotal in protection against HIV type 1 infection. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[55] W. Gong,et al. Monocyte Chemotactic Protein-2 Activates CCR5 and Blocks CD4/CCR5-mediated HIV-1 Entry/Replication* , 1998, The Journal of Biological Chemistry.
[56] William C. Olson,et al. Amino-Terminal Substitutions in the CCR5 Coreceptor Impair gp120 Binding and Human Immunodeficiency Virus Type 1 Entry , 1998, Journal of Virology.
[57] M. Carrington,et al. Novel alleles of the chemokine-receptor gene CCR5. , 1997, American journal of human genetics.
[58] A. Trkola,et al. Co-receptors for HIV-1 entry. , 1997, Current opinion in immunology.
[59] S. Ullrich,et al. STRL22 is a receptor for the CC chemokine MIP-3alpha. , 1997, Biochemical and biophysical research communications.
[60] M. Metzker,et al. The extent of genetic variation in the CCR5 gene , 1997, Nature Genetics.
[61] D. Weissman,et al. Inherited Resistance to HIV-1 Conferred by an Inactivating Mutation in CC Chemokine Receptor 5: Studies in Populations with Contrasting Clinical Phenotypes, Defined Racial Background, and Quantified Risk , 1997, Molecular medicine.
[62] J J Goedert,et al. Genetic Restriction of HIV-1 Infection and Progression to AIDS by a Deletion Allele of the CKR5 Structural Gene , 1996, Science.
[63] Marc Parmentier,et al. Resistance to HIV-1 infection in Caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene , 1996, Nature.
[64] P. Gray,et al. Molecular Cloning and Functional Characterization of a Novel Human CC Chemokine Receptor (CCR5) for RANTES, MIP-1β, and MIP-1α* , 1996, The Journal of Biological Chemistry.
[65] Paul E. Kennedy,et al. HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor , 1996, Science.
[66] W. Farrar,et al. Structural domains of interleukin-2 receptor beta critical for signal transduction: kinase association and nuclear complex-formation. , 1995, The Biochemical journal.
[67] Jerome A. Zack,et al. HIV-1 entry into quiescent primary lymphocytes: Molecular analysis reveals a labile, latent viral structure , 1990, Cell.