Entzündungshemmende Sesquiterpenlactone von Achillea setacea

From the aerial parts of Achillea setacea W. & K. (Asteraceae) the main sesquiterpenes were isolated. Their structures were determined by means of 2D-NMR and MS as 11,13-dehydrodeacetylmatricarin (1) (=14-deoxylactucin), rupicolin A (2), and rupicolin B (3). These are the first compounds with an α-methylene-γ-lactone structure isolated from a species belonging to the Achillea millefolium aggregate