Geriatric epilepsy: Research and clinical directions for the future
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[1] Dieter Schmidt,et al. Modern antiepileptic drug development has failed to deliver: Ways out of the current dilemma , 2011, Epilepsia.
[2] L. Mucke,et al. Amyloid-β/Fyn–Induced Synaptic, Network, and Cognitive Impairments Depend on Tau Levels in Multiple Mouse Models of Alzheimer's Disease , 2011, The Journal of Neuroscience.
[3] Shlomo Shinnar,et al. Long-term mortality in childhood-onset epilepsy. , 2010, The New England journal of medicine.
[4] W. Weiner,et al. Quality improvement in neurology: AAN epilepsy quality measures , 2010, Neurology.
[5] Yadong Huang,et al. Apolipoprotein E4 Causes Age- and Tau-Dependent Impairment of GABAergic Interneurons, Leading to Learning and Memory Deficits in Mice , 2010, The Journal of Neuroscience.
[6] Cornelis J Stam,et al. EEG abnormalities in early and late onset Alzheimer's disease: understanding heterogeneity , 2010, Journal of Neurology, Neurosurgery & Psychiatry.
[7] Jürgen Götz,et al. Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models , 2010, Cell.
[8] L. Mucke,et al. Amyloid-β–induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks , 2010, Nature Neuroscience.
[9] M. Manfredi,et al. Intravenous Levetiracetam as first‐line treatment of status epilepticus in the elderly , 2010, Acta neurologica Scandinavica.
[10] M. Cook,et al. Surgery for temporal lobe epilepsy associated with mesial temporal sclerosis in the older patient: A long‐term follow‐up , 2010, Epilepsia.
[11] D. Berlowitz,et al. Choice of Initial Antiepileptic Drug for Older Veterans: Possible Pharmacokinetic Drug Interactions with Existing Medications , 2010, Journal of the American Geriatrics Society.
[12] J. Lucas,et al. Tau-knockout mice show reduced GSK3-induced hippocampal degeneration and learning deficits , 2010, Neurobiology of Disease.
[13] I. Slutsky,et al. Amyloid-β as a positive endogenous regulator of release probability at hippocampal synapses , 2009, Nature Neuroscience.
[14] Patrick Kwan,et al. Epilepsy in later life , 2009, The Lancet Neurology.
[15] J. Cramer,et al. New‐onset geriatric epilepsy care: Race, setting of diagnosis, and choice of antiepileptic drug , 2009, Epilepsia.
[16] L. Mucke,et al. Epilepsy and cognitive impairments in Alzheimer disease. , 2009, Archives of neurology.
[17] D. Berlowitz,et al. Improving Methods for Measuring Quality of Care , 2009, Medical care research and review : MCRR.
[18] Sylvain Rheims,et al. Amyloid β-Induced Neuronal Hyperexcitability Triggers Progressive Epilepsy , 2009, The Journal of Neuroscience.
[19] A. Lieberman,et al. Tau deletion exacerbates the phenotype of Niemann-Pick type C mice and implicates autophagy in pathogenesis. , 2009, Human molecular genetics.
[20] D. Berlowitz,et al. New‐Onset Epilepsy Risk Factors in Older Veterans , 2009, Journal of the American Geriatrics Society.
[21] K. Werhahn. Epilepsy in the elderly. , 2009, Deutsches Arzteblatt international.
[22] A. Palmeri,et al. Picomolar Amyloid-β Positively Modulates Synaptic Plasticity and Memory in Hippocampus , 2008, The Journal of Neuroscience.
[23] P. Calabresi,et al. Levetiracetam in newly diagnosed late-onset post-stroke seizures: A prospective observational study , 2008, Epilepsy Research.
[24] A. Jacoby. Epilepsy and stigma: An update and critical review , 2008, Current neurology and neuroscience reports.
[25] Arthur Konnerth,et al. Clusters of Hyperactive Neurons Near Amyloid Plaques in a Mouse Model of Alzheimer's Disease , 2008, Science.
[26] Bo Lu,et al. Exercise, diet, health behaviors, and risk factors among persons with epilepsy based on the California Health Interview Survey, 2005 , 2008, Epilepsy & Behavior.
[27] B. Uthman,et al. Topiramate in older patients with partial‐onset seizures: A pilot double‐blind, dose‐comparison study , 2008, Epilepsia.
[28] J. Cramer,et al. Trends in antiepileptic drug prescribing for older patients with new-onset epilepsy: 2000–2004 , 2008, Neurology.
[29] L. Mucke,et al. Enkephalin Elevations Contribute to Neuronal and Behavioral Impairments in a Transgenic Mouse Model of Alzheimer's Disease , 2008, The Journal of Neuroscience.
[30] P. Rutecki,et al. Growing old with epilepsy: the neglected issue of cognitive and brain health in aging and elder persons with chronic epilepsy , 2008, Epilepsia.
[31] Dieter Schmidt,et al. Modern management of epilepsy: A practical approach , 2008, Epilepsy & Behavior.
[32] Guojun Bu,et al. Endocytosis Is Required for Synaptic Activity-Dependent Release of Amyloid-β In Vivo , 2008, Neuron.
[33] N. Pachana,et al. Stigma, seizure frequency and quality of life: The impact of epilepsy in late adulthood , 2008, Seizure.
[34] C. Hommet,et al. Epilepsy and Dementia in the Elderly , 2008, Dementia and Geriatric Cognitive Disorders.
[35] G. Maele,et al. Seizures and epilepsy in patients with lacunar strokes , 2007, Journal of the Neurological Sciences.
[36] J. Cramer,et al. What constitutes high quality of care for adults with epilepsy? , 2007, Neurology.
[37] Bruce Hermann,et al. Cognitive Progression in Epilepsy , 2007, Neuropsychology Review.
[38] A. García-Escrivá,et al. [The use of levetiracetam in monotherapy in post-stroke seizures in the elderly population]. , 2007, Revista de neurologia.
[39] Anatol C. Kreitzer,et al. Aberrant Excitatory Neuronal Activity and Compensatory Remodeling of Inhibitory Hippocampal Circuits in Mouse Models of Alzheimer's Disease , 2007, Neuron.
[40] L. Mucke,et al. Accelerating Amyloid-β Fibrillization Reduces Oligomer Levels and Functional Deficits in Alzheimer Disease Mouse Models* , 2007, Journal of Biological Chemistry.
[41] L. Gjerstad,et al. An International Multicenter Randomized Double‐Blind Controlled Trial of Lamotrigine and Sustained‐Release Carbamazepine in the Treatment of Newly Diagnosed Epilepsy in the Elderly , 2007, Epilepsia.
[42] L. Mucke,et al. Reducing Endogenous Tau Ameliorates Amyloid ß-Induced Deficits in an Alzheimer's Disease Mouse Model , 2007, Science.
[43] D. Marson,et al. Cognitive functioning over 3 years in community dwelling older adults with chronic partial epilepsy , 2007, Epilepsy Research.
[44] Marc Baltzan,et al. Sleep and aging: 1. Sleep disorders commonly found in older people , 2007, Canadian Medical Association Journal.
[45] Bernardo L Sabatini,et al. Natural Oligomers of the Alzheimer Amyloid-β Protein Induce Reversible Synapse Loss by Modulating an NMDA-Type Glutamate Receptor-Dependent Signaling Pathway , 2007, The Journal of Neuroscience.
[46] J. Wark,et al. Anti-epileptic medication and bone health , 2007, Osteoporosis International.
[47] R. Malinow,et al. AMPAR Removal Underlies Aβ-Induced Synaptic Depression and Dendritic Spine Loss , 2006, Neuron.
[48] M. Canevini,et al. Elderly People and Epilepsy: Cognitive Function , 2006, Epilepsia.
[49] D. Berlowitz,et al. Prescribing Antiepileptics for the Elderly , 2006, Drugs & aging.
[50] J. Duncan,et al. Paroxysmal Motor Disorders of Sleep: The Clinical Spectrum and Differentiation from Epilepsy , 2006, Epilepsia.
[51] P. Derambure,et al. Early epileptic seizures after stroke are associated with increased risk of new-onset dementia , 2006, Journal of Neurology, Neurosurgery & Psychiatry.
[52] R. Lipton,et al. Incidence of epilepsy in a racially diverse, community-dwelling, elderly cohort: Results from the Einstein aging study , 2006, Epilepsy Research.
[53] S. Shinnar,et al. Temporal changes in the incidence of epilepsy in Finland: Nationwide study , 2006, Epilepsy Research.
[54] A. Mrabet,et al. "Introduction to the International Geriatric Epilepsy Symposium". , 2006, La Tunisie medicale.
[55] C. Elger,et al. Surgical Treatment for Refractory Temporal Lobe Epilepsy in the Elderly: Seizure Outcome and Neuropsychological Sequels Compared with a Younger Cohort , 2006, Epilepsia.
[56] Michael Seidenberg,et al. Cognitive prognosis in chronic temporal lobe epilepsy , 2006, Annals of neurology.
[57] Yaakov Stern,et al. Incidence and Predictors of Seizures in Patients with Alzheimer's Disease , 2006, Epilepsia.
[58] D. Marson,et al. Older adults with epilepsy demonstrate cognitive impairments compared with patients with amnestic mild cognitive impairment , 2006, Epilepsy & Behavior.
[59] M. Doran,et al. Clinical phenotypic heterogeneity of Alzheimer's disease associated with mutations of the presenilin–1 gene , 2006, Journal of Neurology.
[60] I. Leppik. Introduction to the International Geriatric Epilepsy Symposium (IGES) , 2006, Epilepsy Research.
[61] Steven Mennerick,et al. Synaptic Activity Regulates Interstitial Fluid Amyloid-β Levels In Vivo , 2005, Neuron.
[62] Samuel Wiebe,et al. Somatic Comorbidity of Epilepsy in the General Population in Canada , 2005, Epilepsia.
[63] A. Rowan. Epilepsy in older adults. Common morbidities influence development, treatment strategies, and expected outcomes. , 2005, Geriatrics.
[64] L. Mucke,et al. Fyn Kinase Induces Synaptic and Cognitive Impairments in a Transgenic Mouse Model of Alzheimer's Disease , 2005, The Journal of Neuroscience.
[65] Bertrand Z. Yeung,et al. Vulnerability of Dentate Granule Cells to Disruption of Arc Expression in Human Amyloid Precursor Protein Transgenic Mice , 2005, The Journal of Neuroscience.
[66] R. Guerrini,et al. Experience with topiramate monotherapy in elderly patients with recent‐onset epilepsy , 2005, Acta neurologica Scandinavica.
[67] M. Morrell,et al. Treatment of epilepsy in adults: expert opinion, 2005 , 2005, Epilepsy & Behavior.
[68] B. Uthman,et al. New onset geriatric epilepsy , 2005, Neurology.
[69] M. Staufenbiel,et al. Neurobehavioral characterization of APP23 transgenic mice with the SHIRPA primary screen , 2005, Behavioural Brain Research.
[70] F. Gilliam,et al. Cognitive Functioning in Community Dwelling Older Adults with Chronic Partial Epilepsy , 2005, Epilepsia.
[71] Azeem Majeed,et al. The Epidemiology of the Comorbidity of Epilepsy in the General Population , 2004, Epilepsia.
[72] P. Derambure,et al. The choice of antiepileptic drugs in newly diagnosed epilepsy: a national French survey. , 2004, Epileptic disorders : international epilepsy journal with videotape.
[73] David H. Cribbs,et al. Aβ Immunotherapy Leads to Clearance of Early, but Not Late, Hyperphosphorylated Tau Aggregates via the Proteasome , 2004, Neuron.
[74] P. J. Bowman,et al. Antiepileptic drug use increases rates of bone loss in older women , 2004, Neurology.
[75] R. Ramsay,et al. Special considerations in treating the elderly patient with epilepsy , 2004, Neurology.
[76] J. Cramer,et al. Potentially Inappropriate Antiepileptic Drugs for Elderly Patients with Epilepsy , 2004, Journal of the American Geriatrics Society.
[77] T. Loddenkemper,et al. Seizure Semiology in the Elderly: A Video Analysis , 2004, Epilepsia.
[78] M. Morrell,et al. Use of levetiracetam in a population of patients aged 65 years and older: a subset analysis of the KEEPER trial , 2003, Epilepsy & Behavior.
[79] Jacob Raber,et al. Neuronal depletion of calcium-dependent proteins in the dentate gyrus is tightly linked to Alzheimer's disease-related cognitive deficits , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[80] A. Beydoun,et al. Safety and tolerability of oxcarbazepine in elderly patients with epilepsy , 2003, Epilepsy & Behavior.
[81] R. Malinow,et al. APP Processing and Synaptic Function , 2003, Neuron.
[82] E. Passaro,et al. Early and late cognitive changes following temporal lobe surgery for epilepsy , 2003, Neurology.
[83] A. Birnbaum,et al. Variability of total phenytoin serum concentrations within elderly nursing home residents , 2003, Neurology.
[84] D. Selkoe. Alzheimer's Disease Is a Synaptic Failure , 2002, Science.
[85] P. J. Bowman,et al. Central Nervous System–Active Medications and Risk for Falls in Older Women , 2002, Journal of the American Geriatrics Society.
[86] J. Morley. A fall is a major event in the life of an older person. , 2002, The journals of gerontology. Series A, Biological sciences and medical sciences.
[87] D. Clair,et al. Brave New Brain: Conquering Mental Illness in the Era of the Genome , 2002, Heredity.
[88] D. Dickson,et al. Enhanced Neurofibrillary Degeneration in Transgenic Mice Expressing Mutant Tau and APP , 2001, Science.
[89] F. Dubeau,et al. Surgery for temporal lobe epilepsy in older patients. , 2001, Journal of neurosurgery.
[90] G. Baker,et al. The quality of life of older people with epilepsy: findings from a UK community study , 2001, Seizure.
[91] A. Rowan. What We Owe Our Seniors with Epilepsy—Thoughts on Quality of Life , 2000, Epilepsy & Behavior.
[92] M. Brodie,et al. Epilepsy in elderly people , 2000, The Lancet.
[93] C. Broeckhoven,et al. Behavioral Disturbances without Amyloid Deposits in Mice Overexpressing Human Amyloid Precursor Protein with Flemish (A692G) or Dutch (E693Q) Mutation , 2000, Neurobiology of Disease.
[94] M. Brodie,et al. Multicentre, double-blind, randomised comparison between lamotrigine and carbamazepine in elderly patients with newly diagnosed epilepsy , 1999, Epilepsy Research.
[95] J. Hanlon,et al. Association of race and other potential risk factors with nonvertebral fractures in community-dwelling elderly women. , 1999, American journal of epidemiology.
[96] Veerle Baekelandt,et al. Early Phenotypic Changes in Transgenic Mice That Overexpress Different Mutants of Amyloid Precursor Protein in Brain* , 1999, The Journal of Biological Chemistry.
[97] I. Leppik,et al. Antiepileptic Drug Use in Nursing Home Residents: Effect of Age, Gender, and Comedication on Patterns of Use , 1998, Epilepsia.
[98] N R Relkin,et al. Increased apolipoprotein E ϵ4 in epilepsy with senile plaques , 1997, Annals of neurology.
[99] L Forsgren,et al. Incidence and Clinical Characterization of Unprovoked Seizures in Adults: A Prospective Population‐Based Study , 1996, Epilepsia.
[100] W. Hauser,et al. Dementia and adult-onset unprovoked seizures , 1996, Neurology.
[101] D. Borchelt,et al. Age-related CNS disorder and early death in transgenic FVB/N mice overexpressing Alzheimer amyloid precursor proteins , 1995, Neuron.
[102] B. Stegmayr,et al. Trends in Incidence, Case‐Fatality Rate, and Severity of Stroke in Northern Sweden, 1985‐1991 , 1994, Stroke.
[103] T. Lempert,et al. Syncope: A videometric analysis of 56 episodes of transient cerebral hypoxia , 1994, Annals of neurology.
[104] I. Leppik,et al. Antiepileptics in the elderly. Pharmacoepidemiology and pharmacokinetics. , 1994, Archives of family medicine.
[105] Laurie A. Miller,et al. Senile plaques in temporal lobe epilepsy , 1994, Acta Neuropathologica.
[106] W. Hauser,et al. Incidence of Epilepsy and Unprovoked Seizures in Rochester, Minnesota: 1935–1984 , 1993, Epilepsia.
[107] B. Aublet,et al. Survey of Seizure Disorders in the French Southwest. I. Incidence of Epileptic Syndromes , 1990, Epilepsia.
[108] J. Morris,et al. Advanced Alzheimer's disease is a risk factor for late-onset seizures. , 1990, Archives of neurology.
[109] J. Cramer,et al. Results of a Nationwide Veterans Administration Cooperative Study Comparing the Efficacy and Toxicity of Carbamazepine, Phenobarbital, Phenytoin, and Primidone , 1987, Epilepsia.
[110] W. Hauser,et al. Seizures and myoclonus in patients with Alzheimer's disease , 1986, Neurology.
[111] J. Cramer,et al. Comparison of carbamazepine, phenobarbital, phenytoin, and primidone in partial and secondarily generalized tonic-clonic seizures. , 1985, The New England journal of medicine.
[112] Erik D Roberson,et al. Quantifying biomarkers of cognitive dysfunction and neuronal network hyperexcitability in mouse models of Alzheimer's disease: depletion of calcium-dependent proteins and inhibitory hippocampal remodeling. , 2011, Methods in molecular biology.
[113] T. Alsaadi,et al. Levetiracetam monotherapy for elderly patients with epilepsy , 2004, Seizure.
[114] A. Hammer,et al. The Tolerability of Lamotrigine in Elderly Patients With Epilepsy , 2001, Drugs & aging.
[115] W. Hauser,et al. A population-based study of seizures after traumatic brain injuries. , 1998, The New England journal of medicine.
[116] C. Bieberich,et al. The Alzheimer's Aβ peptide induces neurodegeneration and apoptotic cell death in transgenic mice , 1995, Nature Genetics.