Optical genome mapping identifies rare structural variations as predisposition factors associated with severe COVID-19
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A. Hoischen | V. Bafna | M. Zody | A. Randolph | T. Illig | A. Hastie | S. Bacanu | J. Chou | C. Brownstein | A. Beggs | R. Kanagal-Shamanna | B. Levy | A. Rojiani | R. Kolhe | O. Fedrigo | Chi-Yu Jill Lai | M. Byrska-Bishop | A. Chaubey | M. Schieck | Farooq O. Al-Ajli | E. Jarvis | N. Sahajpal | A. Mondal | S. Jalnapurkar | S. R. Dehkordi | Caspar I. van der Made
[1] A. Hoischen,et al. Next-generation cytogenetics: Comprehensive assessment of 52 hematological malignancy genomes by optical genome mapping. , 2021, American journal of human genetics.
[2] J. Marchini,et al. Pan-ancestry exome-wide association analyses of COVID-19 outcomes in 586,157 individuals , 2021, The American Journal of Human Genetics.
[3] Alexander Hoischen,et al. Optical genome mapping enables constitutional chromosomal aberration detection. , 2021, American journal of human genetics.
[4] William T. Harvey,et al. Haplotype-resolved diverse human genomes and integrated analysis of structural variation , 2021, Science.
[5] S. Ceri,et al. Post-Mendelian genetic model in COVID-19 , 2021, medRxiv.
[6] Vineet Bafna,et al. FaNDOM: Fast nested distance-based seeding of optical maps , 2021, Patterns.
[7] S. Ludovisi,et al. Association of Toll-like receptor 7 variants with life-threatening COVID-19 disease in males , 2020, medRxiv.
[8] C. Pasquier,et al. Computational search of hybrid human/ SARS-CoV-2 dsRNA reveals unique viral sequences that diverge from those of other coronavirus strains , 2020 .
[9] Jennifer Abbasí. Younger Adults Caught in COVID-19 Crosshairs as Demographics Shift. , 2020, JAMA.
[10] S. Mukherjee,et al. In silico analyses on the comparative sensing of SARS-CoV-2 mRNA by intracellular TLRs of human , 2020, bioRxiv.
[11] Jianchao Wei,et al. p53 promotes ZDHHC1-mediated IFITM3 palmitoylation to inhibit Japanese encephalitis virus replication , 2020, PLoS pathogens.
[12] Barbara B. Shih,et al. Genetic mechanisms of critical illness in COVID-19 , 2020, Nature.
[13] Jacques Fellay,et al. Inborn errors of type I IFN immunity in patients with life-threatening COVID-19 , 2020, Science.
[14] P. Rosenstiel,et al. Circulating levels of soluble Dipeptidylpeptidase-4 are reduced in human subjects hospitalized for severe COVID-19 infections , 2020, International Journal of Obesity.
[15] S. Smirnakis,et al. Characteristics and Outcomes of Latinx Patients With COVID-19 in Comparison With Other Ethnic and Racial Groups , 2020, Open forum infectious diseases.
[16] F. Kirchhoff,et al. IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition in vitro , 2020, Nature Communications.
[17] D. Cummings,et al. The Role of Host Genetic Factors in Coronavirus Susceptibility: Review of Animal and Systematic Review of Human Literature , 2020, The American Journal of Human Genetics.
[18] J. Schuurs-Hoeijmakers,et al. Presence of Genetic Variants Among Young Men With Severe COVID-19. , 2020, JAMA.
[19] Wei Zhang,et al. Association Between ABO Blood Group System and COVID-19 Susceptibility in Wuhan , 2020, Frontiers in Cellular and Infection Microbiology.
[20] Eun-Kyeong Jo,et al. COVID-19 Patients Upregulate Toll-like Receptor 4-mediated Inflammatory Signaling That Mimics Bacterial Sepsis , 2020, bioRxiv.
[21] Nicolas Carlier,et al. Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients , 2020, Science.
[22] K. Bhaskaran,et al. OpenSAFELY: factors associated with COVID-19 death in 17 million patients , 2020, Nature.
[23] J. Erdmann,et al. Genomewide Association Study of Severe Covid-19 with Respiratory Failure , 2020, The New England journal of medicine.
[24] D. Cummings,et al. The Role of Host Genetic Factors in Coronavirus Susceptibility: Review of Animal and Systematic Review of Human Literature , 2020, medRxiv.
[25] J. Jamaluddin,et al. Population-specific profiling of CCL3L1 copy number of the three major ethnic groups in Malaysia and the implication on HIV susceptibility. , 2020, Gene.
[26] U. Maulik,et al. Study of cell to cell transmission of SARS CoV 2 virus particle using gene network from microarray data , 2020, bioRxiv.
[27] P. Horby,et al. Features of 20 133 UK patients in hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: prospective observational cohort study , 2020, BMJ.
[28] D. Nikoloudis,et al. The frequency of combined IFITM3 haplotype involving the reference alleles of both rs12252 and rs34481144 is in line with COVID-19 standardized mortality ratio of ethnic groups in England , 2020, PeerJ.
[29] F. Martinez,et al. Severe Covid-19. , 2020, The New England journal of medicine.
[30] The COVID-19 Host Genetics Initiative. The COVID-19 Host Genetics Initiative, a global initiative to elucidate the role of host genetic factors in susceptibility and severity of the SARS-CoV-2 virus pandemic , 2020, European Journal of Human Genetics.
[31] Jianhong Lu,et al. The MERS-CoV Receptor DPP4 as a Candidate Binding Target of the SARS-CoV-2 Spike , 2020, iScience.
[32] A. Harries,et al. Faculty Opinions recommendation of Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area. , 2020 .
[33] R. Schwartz,et al. Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19 , 2020, Cell.
[34] Eun Ji Kim,et al. Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area. , 2020, JAMA.
[35] Jing Shi,et al. Risk factors for severity and mortality in adult COVID-19 inpatients in Wuhan , 2020, Journal of Allergy and Clinical Immunology.
[36] C. Pasquier,et al. Computational search of hybrid human/SARS-CoV-2 dsRNA reveals unique viral sequences that diverge from those of other coronavirus strains , 2020, bioRxiv.
[37] Lei Liu,et al. Relationship between the ABO Blood Group and the COVID-19 Susceptibility , 2020, medRxiv.
[38] Erin E. Mulvihill,et al. Dipeptidyl Peptidase-4 at the Interface Between Inflammation and Metabolism , 2020, Clinical medicine insights. Endocrinology and diabetes.
[39] J. Xiang,et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study , 2020, The Lancet.
[40] Andrea Marzi,et al. Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses , 2020, Nature Microbiology.
[41] G. Gao,et al. A Novel Coronavirus from Patients with Pneumonia in China, 2019 , 2020, The New England journal of medicine.
[42] M. Shimada,et al. Vildagliptin‐induced ground‐glass nodules mimicking lung metastases in a cancer patient receiving Lactobacillus probiotic supplementation , 2020, Thoracic cancer.
[43] A. Torrelo,et al. EDA, EDAR, EDARADD and WNT10A allelic variants in patients with ectodermal derivative impairment in the Spanish population , 2019, Orphanet Journal of Rare Diseases.
[44] Christophe Dessimoz,et al. Structural variant calling: the long and the short of it , 2019, Genome Biology.
[45] R. Lale,et al. Dual UTR-A novel 5′ untranslated region design for synthetic biology applications , 2019, bioRxiv.
[46] David K. Meyerholz,et al. IFN-I response timing relative to virus replication determines MERS coronavirus infection outcomes. , 2019, The Journal of clinical investigation.
[47] Evan E Eichler,et al. Genetic Variation, Comparative Genomics, and the Diagnosis of Disease. , 2019, The New England journal of medicine.
[48] Ryan L. Collins,et al. Multi-platform discovery of haplotype-resolved structural variation in human genomes , 2017, Nature Communications.
[49] Pui-Yan Kwok,et al. Genome maps across 26 human populations reveal population-specific patterns of structural variation , 2019, Nature Communications.
[50] F. Borrego,et al. CD300 receptor family in viral infections , 2018, European journal of immunology.
[51] A. Smahi,et al. First homozygous large deletion in EDARADD gene associated with a severe form of anhidrotic ectodermal dysplasia , 2018, Journal of the European Academy of Dermatology and Venereology : JEADV.
[52] H. Noels,et al. Reduced post-operative DPP4 activity associated with worse patient outcome after cardiac surgery , 2018, Scientific Reports.
[53] Guillaume Bourque,et al. Human copy number variants are enriched in regions of low mappability , 2015, bioRxiv.
[54] E. Hwang,et al. Reduction of soluble dipeptidyl peptidase 4 levels in plasma of patients infected with Middle East respiratory syndrome coronavirus , 2018, Virology.
[55] Haizhou Wang,et al. Endoplasmic Reticulum Transmembrane Proteins ZDHHC1 and STING Both Act as Direct Adaptors for IRF3 Activation in Teleost , 2017, The Journal of Immunology.
[56] Kevin J. McHugh,et al. Epigenetic and Transcriptomic Regulation of Lung Repair during Recovery from Influenza Infection. , 2017, The American journal of pathology.
[57] C. Klemann,et al. Cut to the chase: a review of CD26/dipeptidyl peptidase‐4's (DPP4) entanglement in the immune system , 2016, Clinical and experimental immunology.
[58] A. Smahi,et al. A novel missense mutation in the gene EDARADD associated with an unusual phenotype of hypohidrotic ectodermal dysplasia , 2016, American journal of medical genetics. Part A.
[59] O. Schwartz,et al. The Phosphatidylserine and Phosphatidylethanolamine Receptor CD300a Binds Dengue Virus and Enhances Infection , 2015, Journal of Virology.
[60] Sky W. Brubaker,et al. Innate immune pattern recognition: a cell biological perspective. , 2015, Annual review of immunology.
[61] Zhengfan Jiang,et al. The kinase MST4 limits inflammatory responses through direct phosphorylation of the adaptor TRAF6 , 2015, Nature Immunology.
[62] Vitor R. C. Aguiar,et al. Mapping Bias Overestimates Reference Allele Frequencies at the HLA Genes in the 1000 Genomes Project Phase I Data , 2014, G3: Genes, Genomes, Genetics.
[63] D. Reinhold,et al. DPP4-directed therapeutic strategies for MERS-CoV , 2014, The Lancet Infectious Diseases.
[64] H. Makino,et al. Sarcoid-like lung granulomas in a hemodialysis patient treated with a dipeptidyl peptidase-4 inhibitor , 2014, Clinical kidney journal.
[65] Jamie K. Scott,et al. Complete haplotype sequence of the human immunoglobulin heavy-chain variable, diversity, and joining genes and characterization of allelic and copy-number variation. , 2013, American journal of human genetics.
[66] Cheuk-Kwan Sun,et al. Paradoxical impairment of angiogenesis, endothelial function and circulating number of endothelial progenitor cells in DPP4-deficient rat after critical limb ischemia , 2013, Stem Cell Research & Therapy.
[67] C. Schalkwijk,et al. Loss of DPP4 activity is related to a prothrombogenic status of endothelial cells: implications for the coronary microvasculature of myocardial infarction patients , 2011, Basic Research in Cardiology.
[68] S. Akira,et al. TRAF6 Establishes Innate Immune Responses by Activating NF-κB and IRF7 upon Sensing Cytosolic Viral RNA and DNA , 2009, PloS one.
[69] A. Smahi,et al. Autosomal dominant anhidrotic ectodermal dysplasias at the EDARADD locus , 2007, Human mutation.
[70] S. Akira,et al. Pathogen Recognition and Innate Immunity , 2006, Cell.
[71] A. Smahi,et al. The NF-kappaB signalling pathway in human diseases: from incontinentia pigmenti to ectodermal dysplasias and immune-deficiency syndromes. , 2002, Human molecular genetics.
[72] Thomas D. Schmittgen,et al. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. , 2001, Methods.
[73] Robert E. Pieroni,et al. Allergy and Clinical Immunology , 1981 .