Estimation of pore diameter for intraparticle fluid flow in bidisperse porous chromatographic particles

Abstract A quantitative method is developed and presented for estimating the mean pore diameter, d pore , that could allow intraparticle fluid flow in the macroporous region of adsorbent particles with a bidisperse porous structure packed in a column. The method is used to estimate the value of d pore that is required to obtain specified values of the fraction, F , of the column superficial fluid velocity that is flowing through the macroporous region of the adsorbent particles and the value of d pore that is required to obtain specified values of the intraparticle Peclet number, Pe intra .

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