Environmental Toxins and Parkinson's Disease

Introduction 51 Normal Aging and the Nigrostriatal Pathway and PD 51 Idiopathic Parkinson’s Disease 52 Parkinsonism 53 Neurodegenerative Parkinsonism versus Parkinson’s Disease: The Role of Oxidative Stress 53 Chemical Exposure-Induced Parkinsonism: The Role of Oxidative Stress 53 MPTP 54 Paraquat 54 Iron 55 Manganese 55 Role of Environmental and Occupational Exposure to Chemicals in Parkinson’s Disease 56 Conclusions 58 A Loving Tribute to Robert G. Feldman, M.D 58 References 58

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