Method for preparing a prion-free bone grafting substitute

The present invention relates to a method of manufacturing a bone graft substitute with soppyeo, more particularly, to a method of manufacturing a secure bone graft substitute no BSE infection risk, characterized in that for processing soppyeo as hypochlorous acid and more than 600 ℃ high temperature will be. According to the invention, the bone and that the structure is very similar to bovine bone fat and organic by effectively removing not cause an immune response when implanted in the body, bone conductivity is excellent, and mad cow disease, the risk of infection to remove prions from the human It can be prepared without a bone graft substitute in a simple way. Bone graft substitutes, soppyeo, hypochlorous acid, mad cow disease, prions