论文信息 - Clinical effectiveness of anti-motion-sickness drugs. Computer review of the literature.

Clinical effectiveness of anti-motion-sickness drugs. Computer review of the literature.

A computer library of the literature on anti-motionsickness drugs has been established at the Navy Institute of Aerospace Medicine at Pensacola, Fla. The overall effectiveness of the antihistamines was 70.6%; for the belladonnas it was 50.1%, and for the phenothiazines, 44.9%. The overall results of British studies indicated a greater effectiveness for the belladonnas than for the antihistamines, which is the reverse of the results of US studies. In a recent series of studies dextroamphetamine was found to be a highly effective anti-motion-sickness drug with an overall effectiveness of 64%. The drugs were found to be more effective for motion sickness during flight than for motion sickness at sea.

[1] R S Kennedy,et al. Comparison of effectiveness of some antimotion sickness drugs using recommended and larger than recommended doses as tested in the slow rotation room. , 1966, Aerospace medicine.

[2] E. Glaser,et al. The prevention of seasickness with hyoscine, benadryl, and phenergan. , 1951, Lancet.

[3] J. Brand,et al. Drugs used in motion sickness. A critical review of the methods available for the study of drugs of potential value in its treatment and of the information which has been derived by these methods. , 1966, Pharmacological reviews.

[4] P. K. Smith,et al. Drugs preventing motion sickness at sea. , 1954, The Journal of pharmacology and experimental therapeutics.

[5] L. Gay,et al. The prevention and treatment of motion sickness; seasickness. , 1949, Bulletin of the Johns Hopkins Hospital.

[6] P. K. Smith,et al. Effect of certain drugs on the incidence of seasickness , 1960, Clinical pharmacology and therapeutics.