Adverse reactions related to hematopoietic stem cell infusion

Objective: to identify adverse reactions related to hematopoietic stem cell infusion. Method: a descriptive exploratory, level II, retrospective study with a quantitative approach, carried out in the BMT unit of the Walter Cantídio University Hospital (HUWC) from August 2008 to July 2012. The research project has been approved by the Research Ethics Committee under Protocol 049.07.12. Results the average age was 42 years and the majority (73.3%) were men. 83.3% of the patient had some sign or symptom during infusion of CTH. On the correlations between adverse reactions and gender (p=0.705), age (p=0.830), storage time (p=0.299), conditioning regimen (p=616) there was no statistically significant correlation. The most common reactions were respiratory (26.4%) and cardiovascular problems (29.5). Conclusion: most patients presented at least one adverse effect, with an equal percentage of occurrence of adverse reaction in the DMSO group at 5% and 10%. Descriptors: Hematopoietic Stem cell transplantation; Dimethyl Sulfoxide; Toxicity

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