PTK7 promotes the malignant properties of cancer stem-like cells in esophageal squamous cell lines

[1]  F. Xue,et al.  The Increased PTK7 Expression Is a Malignant Factor in Cervical Cancer , 2019, Disease markers.

[2]  S. Rottenberg,et al.  Chemotherapy induces an immunosuppressive gene expression signature in residual BRCA1/p53-deficient mouse mammary tumors , 2018 .

[3]  J. Gim,et al.  Biphasic regulation of tumorigenesis by PTK7 expression level in esophageal squamous cell carcinoma , 2018, Scientific Reports.

[4]  E. Schemitsch,et al.  Developing Stem Cell-Based Therapeutic Strategies in Orthopaedic Surgery , 2018, Stem cells international.

[5]  Xiaojun Peng,et al.  Conformationally Induced Off-On Cell Membrane Chemosensor Targeting Receptor Protein-Tyrosine Kinases for in Vivo and in Vitro Fluorescence Imaging of Cancers. , 2018, Journal of the American Chemical Society.

[6]  Ita Novita Sari,et al.  Cancer Stem Cells (CSCs) in Drug Resistance and their Therapeutic Implications in Cancer Treatment , 2018, Stem cells international.

[7]  P. Davis,et al.  Subcellular localisation of the stem cell markers OCT4, SOX2, NANOG, KLF4 and c-MYC in cancer: a review , 2017, Journal of Clinical Pathology.

[8]  H. Clevers,et al.  Cancer stem cells revisited , 2017, Nature Medicine.

[9]  B. Coomber,et al.  Characterization of cancer stem cell drug resistance in the human colorectal cancer cell lines HCT116 and SW480. , 2017, Biochemical and biophysical research communications.

[10]  Xin Hu,et al.  PTK7 is a novel oncogenic target for esophageal squamous cell carcinoma , 2017, World Journal of Surgical Oncology.

[11]  P. Langford,et al.  Haemophilus parasuis cytolethal distending toxin induces cell cycle arrest and p53-dependent apoptosis , 2017, PloS one.

[12]  Tetsuji Yamaguchi,et al.  Enhanced cancer stem cell properties of a mitotically quiescent subpopulation of p75NTR-positive cells in esophageal squamous cell carcinoma , 2017, International journal of oncology.

[13]  Etienne Z. Gnimpieba,et al.  Therapeutic Targeting of PTK7 is Cytotoxic in Atypical Teratoid Rhabdoid Tumors , 2017, Molecular Cancer Research.

[14]  Peng Zhang,et al.  Cripto-1 acts as a functional marker of cancer stem-like cells and predicts prognosis of the patients in esophageal squamous cell carcinoma , 2017, Molecular Cancer.

[15]  T. Kipps,et al.  Wnt5a Signaling in Normal and Cancer Stem Cells , 2017, Stem cells international.

[16]  Ghanbar Mahmoodi Chalbatani,et al.  Analysis of Cancer stem cells (CSCs) in the prevention and treatment of cancer , 2017 .

[17]  Samuel A. Williams,et al.  A PTK7-targeted antibody-drug conjugate reduces tumor-initiating cells and induces sustained tumor regressions , 2017, Science Translational Medicine.

[18]  Won-Sik Shin,et al.  Catalytically defective receptor protein tyrosine kinase PTK7 enhances invasive phenotype by inducing MMP-9 through activation of AP-1 and NF-κB in esophageal squamous cell carcinoma cells , 2016, Oncotarget.

[19]  J. Kwon,et al.  PTK7 regulates radioresistance through nuclear factor-kappa B in esophageal squamous cell carcinoma , 2016, Tumor Biology.

[20]  Xiu-Yun Tian,et al.  PTK7 overexpression in colorectal tumors: Clinicopathological correlation and prognosis relevance , 2016, Oncology reports.

[21]  J. Kinoshita,et al.  Recurrence patterns and risk factors following thoracoscopic esophagectomy with radical lymph node dissection for thoracic esophageal squamous cell carcinoma. , 2016, Molecular and clinical oncology.

[22]  Osamu Kikuchi,et al.  Recent Advances From Basic and Clinical Studies of Esophageal Squamous Cell Carcinoma. , 2015, Gastroenterology.

[23]  P. Aloy,et al.  Isolation of Human Colon Stem Cells Using Surface Expression of PTK7 , 2015, Stem cell reports.

[24]  H. Saya,et al.  Therapeutic strategies targeting cancer stem cells , 2015, Cancer science.

[25]  M. Arnal,et al.  Esophageal cancer: Risk factors, screening and endoscopic treatment in Western and Eastern countries. , 2015 .

[26]  Min-Jung Kim,et al.  Profilin 2 promotes migration, invasion, and stemness of HT29 human colorectal cancer stem cells , 2015, Bioscience, biotechnology, and biochemistry.

[27]  J. Borg,et al.  Overexpression of the Promigratory and Prometastatic PTK7 Receptor Is Associated with an Adverse Clinical Outcome in Colorectal Cancer , 2015, PloS one.

[28]  Minghua Wu,et al.  PTK7 regulates Id1 expression in CD44-high glioma cells. , 2015, Neuro-oncology.

[29]  M. Somerfield,et al.  Molecular testing for selection of patients with lung cancer for epidermal growth factor receptor and anaplastic lymphoma kinase tyrosine kinase inhibitors: american society of clinical oncology endorsement of the college of american pathologists/international association for the study of lung cance , 2015, Journal of oncology practice.

[30]  Mari Mino-Kenudson,et al.  Molecular testing for selection of patients with lung cancer for epidermal growth factor receptor and anaplastic lymphoma kinase tyrosine kinase inhibitors: American Society of Clinical Oncology endorsement of the College of American Pathologists/International Association for the study of lung cance , 2014, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[31]  Kyung-Chul Choi,et al.  Role of the epithelial–mesenchymal transition and its effects on embryonic stem cells , 2014, Experimental & Molecular Medicine.

[32]  Purvesh Khatri,et al.  A meta-analysis of lung cancer gene expression identifies PTK7 as a survival gene in lung adenocarcinoma. , 2014, Cancer research.

[33]  W. Eiermann,et al.  PTK7 expression in triple-negative breast cancer. , 2013, Anticancer research.

[34]  Won-Sik Shin,et al.  Oncogenic role of protein tyrosine kinase 7 in esophageal squamous cell carcinoma , 2013, Cancer science.

[35]  J. Ji,et al.  PTK7 as a novel marker for favorable gastric cancer patient survival , 2012, Journal of surgical oncology.

[36]  U. Hellman,et al.  Proteome profiling of immortalization‐to‐senescence transition of human breast epithelial cells identified MAP2K3 as a senescence‐promoting protein which is downregulated in human breast cancer , 2010, Proteomics. Clinical applications.

[37]  F. Puppo,et al.  The cell polarity PTK7 receptor acts as a modulator of the chemotherapeutic response in acute myeloid leukemia and impairs clinical outcome. , 2010, Blood.

[38]  G. Bossi,et al.  Mutant p53-induced Up-regulation of Mitogen-activated Protein Kinase Kinase 3 Contributes to Gain of Function* , 2010, The Journal of Biological Chemistry.

[39]  C. Beaudry,et al.  MAP-ing glioma invasion: Mitogen-activated protein kinase kinase 3 and p38 drive glioma invasion and progression and predict patient survival , 2007, Molecular Cancer Therapeutics.

[40]  M. Tessier-Lavigne,et al.  PTK7/CCK-4 is a novel regulator of planar cell polarity in vertebrates , 2004, Nature.

[41]  Jiahuai Han,et al.  Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms , 1995, Science.

[42]  T. Mashima,et al.  Cancer Stem Cells (CSCs) as a Rational Therapeutic Cancer Target, and Screening for CSC-targeting Drugs. , 2017, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.

[43]  E. Oki,et al.  Prognostic Significance of Postoperative Complications After Curative Resection for Patients With Esophageal Squamous Cell Carcinoma. , 2017, Annals of surgery.

[44]  Shumei Ma,et al.  Hsp90 regulates autophagy and plays a role in cancer therapy , 2015, Tumor Biology.

[45]  Peter D Siersema,et al.  Esophageal cancer. , 2008, Gastroenterology clinics of North America.

[46]  J. Dick,et al.  Distinct classes of human stem cells that differ in proliferative and self-renewal potential , 2001, Nature Immunology.