Analysis of medical risk factors and outcomes in patients undergoing open versus endovascular abdominal aortic aneurysm repair.

OBJECTIVE The emergence of endovascular repair (ER) for infrarenal abdominal aortic aneurysm (AAA) has provided surgeons with a new technique that should ideally improve patient outcomes. To more accurately characterize the advantages of ER versus traditional/open AAA repair (TOR), we compared the preoperative medical risk factors (PMRFs) and perioperative outcomes (PO) of those patients undergoing elective treatment of infrarenal AAA with ER and TOR over a recent 18-month period at our center. METHODS Through our institutional vascular surgery patient registry, all patients undergoing aortic aneurysm repair of any type between December 1999 and June 2001 were identified. Only those patients undergoing elective infrarenal AAA repair were analyzed. Hospital records were examined for all patients, and PMRF and PO were assessed via Society for Vascular Surgery/International Society for Cardiovascular Surgery reporting guidelines. Student t, chi(2), Fisher exact, or Wilcoxon rank sum tests were applied where appropriate to determine differences among PMRF and PO according to method of aneurysm repair. RESULTS During the 18-month study period, a total of 199 aortic aneurysms were repaired at our institution. Ninety-nine elective infrarenal AAA repairs made up the study cohort (ER, n = 33; TOR, n = 66). When examined by method of aneurysm repair, no differences existed in demographics or AAA size. Patients undergoing ER had a significantly greater degree of preoperative pulmonary comorbidity than patients undergoing TOR (P <.001). However, no differences existed in terms of American Society of Anesthesiologists classification or cardiac (P =.52), cerebrovascular (P =.44), diabetic (P =.51), hypertensive (P =.90), hyperlipidemia (P =.91) or renal (P =.23) comorbidities between the two groups. Perioperative morbidity and mortality rates were also not significantly different by method of repair. ER was associated with shorter operative time, intensive care unit stay, and overall hospital length of stay (P <.0001). However, subsequent operative procedures related to the AAA repair were performed more frequently after ER (TOR = 1.5% versus ER = 15.2%; P = 0.015). CONCLUSION These results suggest that ER offers improvements in hospital convalescent and operating room times but no beneficial impact on overall morbidity and mortality rates when similar PMRFs exist, especially when used at medical centers where low morbidity and mortality rates are already established for TOR. Other centers performing ER should undertake such an analysis to assess its impact on their patients.

[1]  D. E. Szilagyi The problem of healing of endovascular stent grafts in the repair of abdominal aortic aneurysms. , 2001, Journal of vascular surgery.

[2]  S. Money,et al.  Comparison of open transabdominal AAA repair with endovascular AAA repair in reduction of postoperative stress response , 2001 .

[3]  R. Rutherford,et al.  Recommended standards for reports dealing with lower extremity ischemia: revised version. , 1997, Journal of vascular surgery.

[4]  M. Stewart,et al.  Late abdominal aortic aneurysm rupture after AneuRx repair: a report of three cases. , 2000, Journal of vascular surgery.

[5]  G. White What are the Causes of Endotension? , 2001, Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists.

[6]  W. Sapirstein,et al.  The Food and Drug Administration approval of endovascular grafts for abdominal aortic aneurysm: an 18-month retrospective. , 2001, Journal of vascular surgery.

[7]  K. Johnston,et al.  Nonruptured abdominal aortic aneurysm: six-year follow-up results from the multicenter prospective Canadian aneurysm study. Canadian Society for Vascular Surgery Aneurysm Study Group. , 1994, Journal of vascular surgery.

[8]  H. Gelabert,et al.  Endovascular, transperitoneal, and retroperitoneal abdominal aortic aneurysm repair: results and costs. , 1999, Journal of vascular surgery.

[9]  J. Hedley-Whyte,et al.  Prediction of outcome of surgery and anesthesia in patients over 80. , 1979, JAMA.

[10]  K. Johnston,et al.  The United Kingdom Small Aneurysm Trial: implications for surgical treatment of abdominal aortic aneurysms. , 1999, Journal of vascular surgery.

[11]  G. White,et al.  Comparison of first- and second-generation prostheses for endoluminal repair of abdominal aortic aneurysms: a 6-year study with life table analysis. , 2000, Journal of Vascular Surgery.

[12]  J. Collin,et al.  Endovascular treatment of abdominal aortic aneurysm: a failed experiment , 2001, The British journal of surgery.

[13]  Pascal Desgranges,et al.  Incidence and risk factors of late rupture, conversion, and death after endovascular repair of infrarenal aortic aneurysms: The EUROSTAR experience , 2000 .

[14]  R. Laheij,et al.  Early complications and endoleaks after endovascular abdominal aortic aneurysm repair: report of a multicenter study. , 2000, Journal of vascular surgery.

[15]  P. Pairolero,et al.  Late survival in abdominal aortic aneurysm patients: the role of selective myocardial revascularization on the basis of clinical symptoms. , 1987, Journal of vascular surgery.

[16]  K. Johnston Multicenter prospective study of nonruptured abdominal aortic aneurysm. Part II. Variables predicting morbidity and mortality. , 1989, Journal of vascular surgery.

[17]  R. Fairman,et al.  Aneurysm sac pressure measurements after endovascular repair of abdominal aortic aneurysms. , 2001, Journal of vascular surgery.

[18]  M. Makaroun,et al.  Quality of Life Assessment in Patients Undergoing Endovascular or Conventional AAA Repair , 2001, Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists.

[19]  D. C. Brewster,et al.  The impact of selective use of dipyridamole-thallium scans and surgical factors on the current morbidity of aortic surgery. , 1992, Journal of vascular surgery.

[20]  K. Ouriel,et al.  An evaluation of the costs to health care institutions of endovascular aortic aneurysm repair. , 2000, Journal of vascular surgery.

[21]  B. Katzen,et al.  Risk stratification and outcomes of transluminal endografting for abdominal aortic aneurysm: 7-year experience and long-term follow-up. , 2001, Journal of vascular and interventional radiology : JVIR.

[22]  W. Mali,et al.  Concerns for the durability of the proximal abdominal aortic aneurysm endograft fixation from a 2-year and 3-year longitudinal computed tomography angiography study. , 2001, Journal of vascular surgery.

[23]  F. Veith,et al.  Increasing Incidence of Midterm and Long-Term Complications After Endovascular Graft Repair of Abdominal Aortic Aneurysms: A Note of Caution Based on a 9-Year Experience , 2001, Annals of surgery.

[24]  Rodney A. White,et al.  Aneurysm rupture after endovascular repair using the AneuRx stent graft. , 2000, Journal of vascular surgery.

[25]  G. White,et al.  Concurrent comparison of endoluminal versus open repair in the treatment of abdominal aortic aneurysms: analysis of 303 patients by life table method. , 1998, Journal of vascular surgery.

[26]  A. Lumsden,et al.  Mid-term results after endovascular repair of the abdominal aortic aneurysm. , 2001, Journal of vascular surgery.