AMD3100 plus G-CSF can successfully mobilize CD34+ cells from non-Hodgkin's lymphoma, Hodgkin's disease and multiple myeloma patients previously failing mobilization with chemotherapy and/or cytokine treatment: compassionate use data

[1]  H. Lazarus,et al.  Mobilizing stem cells from normal donors: is it possible to improve upon G-CSF? , 2007, Bone Marrow Transplantation.

[2]  J. Dipersio,et al.  A Mobilizing Regimen of AMD3100 and G-CSF Increases Stem Cell Collection in Patients with Hodgkin’s Disease, and PK Is Similar to That of Non-Cancer Patients. , 2006 .

[3]  E. Estey,et al.  Massive Mobilization of AML Cells into Circulation by Disruption of Leukemia/Stroma Cell Interactions Using CXCR4 Antagonist AMD3100: First Evidence in Patients and Potential for Abolishing Bone Marrow Microenvironment-Mediated Resistance. , 2006 .

[4]  G. Ehninger,et al.  Steady State Mobilization of Autologous Blood Stem Cells Using G-CSF and AMD3100 in Patients with Multiple Myeloma (MM). , 2006 .

[5]  T. Ley,et al.  AMD3100 Mobilizes Acute Promyelocytic Leukemia Cells from the Bone Marrow into the Peripheral Blood and Sensitizes Leukemia Cells to Chemotherapy. , 2005 .

[6]  M. Tormo,et al.  Impact of different strategies of second-line stem cell harvest on the outcome of autologous transplantation in poor peripheral blood stem cell mobilizers , 2005, Bone Marrow Transplantation.

[7]  Hirokazu Tamamura,et al.  Small peptide inhibitors of the CXCR4 chemokine receptor (CD184) antagonize the activation, migration, and antiapoptotic responses of CXCL12 in chronic lymphocytic leukemia B cells. , 2005, Blood.

[8]  J. Dipersio,et al.  The use of AMD3100 plus G-CSF for autologous hematopoietic progenitor cell mobilization is superior to G-CSF alone. , 2005, Blood.

[9]  B. Wood,et al.  Augmented mobilization and collection of CD34+ hematopoietic cells from normal human volunteers stimulated with granulocyte–colony‐stimulating factor by single‐dose administration of AMD3100, a CXCR4 antagonist , 2005, Transfusion.

[10]  A. Nademanee,et al.  Treatment with AMD3100 in Multiple Myeloma or Non-Hodgkin’s Lymphoma Patients to Increase the Number of Peripheral Blood Stem Cells When Given with a Mobilizing Regimen of Chemotherapy and G-CSF. , 2004 .

[11]  G. Tricot,et al.  AMD3100 Combined with Standard Doses of G-Csf Leads to Rapid, Consistent Mobilization of Hematopoietic Progenitor Cells in Patients with Non-Hodgkin’s Lymphoma (NHL) and Multiple Myeloma. , 2004 .

[12]  G. Tricot,et al.  Successful mobilization of peripheral blood stem cells (PBSCs) with AMD3100 in patients failing to collect with hematopoietic growth factors (HGF) and/or chemotherapy. , 2004, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[13]  P. Stiff,et al.  Analysis of remobilization success in patients undergoing autologous stem cell transplants who fail an initial mobilization: risk factors, cytokine use and cost , 2004, Bone Marrow Transplantation.

[14]  M. Cavazzana‐Calvo,et al.  Successful peripheral blood stem cell harvesting with granulocyte colony-stimulating factor alone after previous mobilization failure. , 2004, Haematologica.

[15]  B. Wood,et al.  Mobilization of hematopoietic progenitor cells in healthy volunteers by AMD3100, a CXCR4 antagonist. , 2003, Blood.

[16]  J. Lévesque,et al.  Disruption of the CXCR4/CXCL12 chemotactic interaction during hematopoietic stem cell mobilization induced by GCSF or cyclophosphamide. , 2003, The Journal of clinical investigation.

[17]  I. Petit,et al.  Current understanding of stem cell mobilization: the roles of chemokines, proteolytic enzymes, adhesion molecules, cytokines, and stromal cells. , 2002, Experimental hematology.

[18]  D. Link,et al.  Mechanisms of mobilization of hematopoietic progenitors with granulocyte colony-stimulating factor , 2002, Current opinion in hematology.

[19]  L. Bendall,et al.  The chemokine receptor CXCR4 enhances integrin-mediated in vitro adhesion and facilitates engraftment of leukemic precursor-B cells in the bone marrow. , 2001, Experimental hematology.

[20]  T. Lapidot.  Mechanism of Human Stem Cell Migration and Repopulation of NOD/SCID and B2mnull NOD/SCID Mice , 2001, Annals of the New York Academy of Sciences.

[21]  A. Hidalgo,et al.  Chemokine stromal cell-derived factor-1alpha modulates VLA-4 integrin-mediated multiple myeloma cell adhesion to CS-1/fibronectin and VCAM-1. , 2001, Blood.

[22]  P. Stiff.  Management strategies for the hard-to-mobilize patient , 1999, Bone Marrow Transplantation.

[23]  Y. Kodera,et al.  Peripheral blood stem cell mobilization and apheresis: analysis of adverse events in 94 normal donors , 1999, Bone Marrow Transplantation.

[24]  L. Schwartzberg,et al.  Second attempts at mobilization of peripheral blood stem cells in patients with initial low CD34+ cell yields. , 1998, Journal of hematotherapy.

[25]  T. Springer,et al.  The Chemokine SDF-1 Is a Chemoattractant for Human CD34+ Hematopoietic Progenitor Cells and Provides a New Mechanism to Explain the Mobilization of CD34+ Progenitors to Peripheral Blood , 1997, The Journal of experimental medicine.

[26]  G. Calandra,et al.  Problems and benefits of an antibiotic compassionate therapy program. , 1987, Reviews of infectious diseases.