RAPPER: the radiogenomics of radiation toxicity.

[1]  Richard Stock,et al.  A 2-stage genome-wide association study to identify single nucleotide polymorphisms associated with development of erectile dysfunction following radiation therapy for prostate cancer. , 2013, International journal of radiation oncology, biology, physics.

[2]  Petra Seibold,et al.  Individual patient data meta-analysis shows no association between the SNP rs1800469 in TGFB and late radiotherapy toxicity. , 2012, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[3]  C. Coles,et al.  Radiotherapy research trials in the UK: secrets of success. , 2012, Clinical oncology (Royal College of Radiologists (Great Britain)).

[4]  M. Sydes,et al.  Independent validation of genes and polymorphisms reported to be associated with radiation toxicity: a prospective analysis study. , 2012, The Lancet. Oncology.

[5]  M. Sydes,et al.  The impact of clinical factors on the development of late radiation toxicity: results from the Medical Research Council RT01 trial (ISRCTN47772397). , 2011, Clinical oncology (Royal College of Radiologists (Great Britain)).

[6]  Catharine M West,et al.  Genetics and genomics of radiotherapy toxicity: towards prediction , 2011, Genome Medicine.

[7]  Alison M Dunning,et al.  No association between SNPs regulating TGF-β1 secretion and late radiotherapy toxicity to the breast: results from the RAPPER study. , 2010, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[8]  Andrzej Polanski,et al.  Establishment of a Radiogenomics Consortium. , 2010, International journal of radiation oncology, biology, physics.

[9]  C. Coles,et al.  A randomised controlled trial of forward-planned radiotherapy (IMRT) for early breast cancer: baseline characteristics and dosimetry results. , 2009, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[10]  Alison M. Dunning,et al.  Normal tissue reactions to radiotherapy: towards tailoring treatment dose by genotype , 2009, Nature Reviews Cancer.

[11]  Lester L. Peters,et al.  Genome-wide association study identifies novel breast cancer susceptibility loci , 2007, Nature.

[12]  Michael Baumann,et al.  Influence of connective tissue diseases on the expression of radiation side effects: a systematic review. , 2006, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[13]  F. B. Sørensen,et al.  Risk of radiation-induced subcutaneous fibrosis in relation to single nucleotide polymorphisms in TGFB1, SOD2, XRCC1, XRCC3, APEX and ATMndash; a study based on DNA from formalin fixed paraffin embedded tissue samples , 2006, International journal of radiation biology.

[14]  S. Roberts,et al.  Lymphocyte radiosensitivity is a significant prognostic factor for morbidity in carcinoma of the cervix. , 2001, International journal of radiation oncology, biology, physics.

[15]  J. Yarnold,et al.  Cellular radiosensitivity and complication risk after curative radiotherapy. , 2000, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[16]  B. Ponder,et al.  Comparison of DNA repair protein expression and activities between human fibroblast cell lines with different radiosensitivities , 2000, International journal of cancer.

[17]  D. Evans,et al.  Heritability of cellular radiosensitivity: a marker of low-penetrance predisposition genes in breast cancer? , 1999, American journal of human genetics.

[18]  J. Peacock,et al.  Describing patients' normal tissue reactions: Concerning the possibility of individualising radiotherapy dose prescriptions based on potential predictive assays of normal tissue radiosensitivity , 1998, International journal of cancer.

[19]  J Nyman,et al.  Prognostic factors for acute and late skin reactions in radiotherapy patients. , 1996, International journal of radiation oncology, biology, physics.

[20]  S M Bentzen,et al.  Relationship between the in vitro radiosensitivity of skin fibroblasts and the expression of subcutaneous fibrosis, telangiectasia, and skin erythema after radiotherapy. , 1996, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[21]  R. Wurm,et al.  Normal tissue radiosensitivity--how important is it? , 1996, Clinical oncology (Royal College of Radiologists (Great Britain)).

[22]  C. West,et al.  Invited review: intrinsic radiosensitivity as a predictor of patient response to radiotherapy. , 1995, The British journal of radiology.

[23]  S. Tucker,et al.  Fibroblast radiosensitivity versus acute and late normal skin responses in patients treated for breast cancer. , 1995, International journal of radiation oncology, biology, physics.

[24]  Bentzen,et al.  Patient-to-Patient Variability in the Expression of Radiation-Induced Normal Tissue Injury. , 1994, Seminars in radiation oncology.

[25]  R. Wurm,et al.  Prediction of normal-tissue tolerance to radiotherapy from in-vitro cellular radiation sensitivity , 1992, The Lancet.

[26]  H D Thames,et al.  Evidence for individual differences in the radiosensitivity of human skin. , 1992, European journal of cancer.

[27]  I. Turesson Individual variation and dose dependency in the progression rate of skin telangiectasia. , 1990, International journal of radiation oncology, biology, physics.

[28]  A Brahme,et al.  Optimization of uncomplicated control for head and neck tumors. , 1990, International journal of radiation oncology, biology, physics.

[29]  A. Kagan,et al.  The importance of genetics for the optimization of radiation therapy. A hypothesis. , 1988, American journal of clinical oncology.