Autofluorescence spectrum of skin: component bands and body site variations

Background/aims: The autofluorescence spectrum of skin consists of a number of overlapping single spectra emitted by fluorescent molecules. The overlapping makes it difficult to distinguish changes in the overall spectrum and the molecular basis for it. We applied curve fitting analysis to decompose the autofluorescence spectrum of normal human skin and studied the variation in different body sites.

[1]  E. Sevick-Muraca,et al.  Quantitative optical spectroscopy for tissue diagnosis. , 1996, Annual review of physical chemistry.

[2]  R. Anderson,et al.  In vivo fluorescence of human skin. , 1989, Archives of dermatology.

[3]  L. Deckelbaum,et al.  Biochemical basis for the difference between normal and atherosclerotic arterial fluorescence. , 1989, Circulation.

[4]  L. Deckelbaum,et al.  In vivo fluorescence of human skin. A potential marker of photoaging. , 1988, Archives of Dermatology.

[5]  T. Terao,et al.  Isolation and characterization of zinc coproporphyrin I: a major fluorescent component in meconium. , 1991, Clinical chemistry.

[6]  M. Liška,et al.  Applications of Numerical Methods in Molecular Spectroscopy , 1994 .

[7]  H. Wulf,et al.  Seasonal variation of skin pigmentation. , 1997, Acta dermato-venereologica.

[8]  F. Urbach,et al.  Narrow-band UV radiation and induction of dermal elastosis and skin cancer. , 1989, Photo-dermatology.

[9]  H. Edwards,et al.  Thermally induced molecular disorder in human stratum corneum lipids compared with a model phospholipid system; FT-Raman spectroscopy. , 1998, Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.

[10]  T J Flotte,et al.  Ultraviolet laser‐induced fluorescence of colonic tissue: Basic biology and diagnostic potential , 1992, Lasers in surgery and medicine.

[11]  Haishan Zeng,et al.  SPECTROSCOPIC AND MICROSCOPIC CHARACTERISTICS OF HUMAN SKIN AUTOFLUORESCENCE EMISSION , 1995, Photochemistry and photobiology.

[12]  N Kollias,et al.  Endogenous skin fluorescence includes bands that may serve as quantitative markers of aging and photoaging. , 1998, The Journal of investigative dermatology.

[13]  F. Goñi,et al.  The components of merocyanine-540 absorption spectra in aqueous, micellar and bilayer environments. , 1992, European journal of biochemistry.