PIDD death-domain phosphorylation by ATM controls prodeath versus prosurvival PIDDosome signaling.

[1]  R. Johnstone,et al.  PIDDosome-independent tumor suppression by Caspase-2 , 2012, Cell Death and Differentiation.

[2]  A. Villunger,et al.  Neuronal caspase 2 activity and function requires RAIDD, but not PIDD , 2012, The Biochemical journal.

[3]  Aleksey A. Porollo,et al.  Tumor-suppressing Function of Caspase-2 Requires Catalytic Site Cys-320 and Site Ser-139 in Mice* , 2012, The Journal of Biological Chemistry.

[4]  J. Tschopp,et al.  PIDD orchestrates translesion DNA synthesis in response to UV irradiation , 2011, Cell Death and Differentiation.

[5]  S. Elledge,et al.  The DNA damage response: making it safe to play with knives. , 2010, Molecular cell.

[6]  B. Zhivotovsky,et al.  The unpredictable caspase-2: what can it do? , 2010, Trends in cell biology.

[7]  Sharad Kumar Caspase 2 in apoptosis, the DNA damage response and tumour suppression: enigma no more? , 2009, Nature Reviews Cancer.

[8]  D. Green,et al.  Characterization of cytoplasmic caspase-2 activation by induced proximity. , 2009, Molecular cell.

[9]  Yu Pan,et al.  Knockdown of Chk1 sensitizes human colon carcinoma HCT116 cells in a p53-dependent manner to lidamycin through abrogation of a G2/M checkpoint and induction of apoptosis , 2009, Cancer biology & therapy.

[10]  S. Benchimol,et al.  DNA damage- and stress-induced apoptosis occurs independently of PIDD , 2009, Apoptosis.

[11]  G Melino,et al.  Ordering of caspases in cells undergoing apoptosis by the intrinsic pathway , 2009, Cell Death and Differentiation.

[12]  C. Hawkins,et al.  Caspase-2: controversial killer or checkpoint controller? , 2009, Apoptosis.

[13]  B. Zhivotovsky,et al.  DISC-mediated activation of caspase-2 in DNA damage-induced apoptosis , 2009, Oncogene.

[14]  J. Tschopp,et al.  Caspase-2 activation in the absence of PIDDosome formation , 2009, The Journal of cell biology.

[15]  P. Bouillet,et al.  A tumor suppressor function for caspase-2 , 2009, Proceedings of the National Academy of Sciences.

[16]  M. Meuth,et al.  ATR and Chk1 Suppress a Caspase-3–Dependent Apoptotic Response Following DNA Replication Stress , 2009, PLoS genetics.

[17]  P. Chan,et al.  The PIDDosome mediates delayed death of hippocampal CA1 neurons after transient global cerebral ischemia in rats , 2008, Proceedings of the National Academy of Sciences.

[18]  A. Barsotti,et al.  A role for caspase 2 and PIDD in the process of p53-mediated apoptosis , 2008, Proceedings of the National Academy of Sciences.

[19]  S. Ghosh,et al.  Shared Principles in NF-κB Signaling , 2008, Cell.

[20]  J. Tschopp,et al.  p53-induced protein with a death domain (PIDD) isoforms differentially activate nuclear factor-kappaB and caspase-2 in response to genotoxic stress , 2008, Oncogene.

[21]  Hao Wu,et al.  Serveur Académique Lausannois SERVAL serval.unil.ch , 2022 .

[22]  J. Tschopp,et al.  Autoproteolysis of PIDD marks the bifurcation between pro‐death caspase‐2 and pro‐survival NF‐κB pathway , 2007, The EMBO journal.

[23]  B. Zhivotovsky,et al.  Functional connection between p53 and caspase-2 is essential for apoptosis induced by DNA damage , 2006, Oncogene.

[24]  P. Krammer,et al.  Caspase-2 is activated at the CD95 death-inducing signaling complex in the course of CD95-induced apoptosis. , 2006, Blood.

[25]  S. Miyamoto,et al.  PIDD: A Switch Hitter , 2005, Cell.

[26]  J. Tschopp,et al.  PIDD Mediates NF-κB Activation in Response to DNA Damage , 2005, Cell.

[27]  L. Salmena,et al.  Apoptosis caused by p53-induced protein with death domain (PIDD) depends on the death adapter protein RAIDD. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[28]  S. Lowe,et al.  Intrinsic tumour suppression , 2004, Nature.

[29]  J. Tschopp,et al.  The PIDDosome, a Protein Complex Implicated in Activation of Caspase-2 in Response to Genotoxic Stress , 2004, Science.

[30]  D. Vaux,et al.  A novel Apaf-1–independent putative caspase-2 activation complex , 2002, The Journal of cell biology.

[31]  Yunping Lin,et al.  Pidd, a new death-domain–containing protein, is induced by p53 and promotes apoptosis , 2000, Nature Genetics.

[32]  J. Telliez,et al.  LRDD, a novel leucine rich repeat and death domain containing protein. , 2000, Biochimica et biophysica acta.

[33]  Vishva M. Dixit,et al.  RAIDD is a new 'death' adaptor molecule , 1997, Nature.

[34]  D. Green,et al.  In situ trapping of activated initiator caspases reveals a role for caspase-2 in heat shock-induced apoptosis , 2006, Nature Cell Biology.