Host Epac1 is required for cAMP-mediated invasion by Trypanosoma cruzi.

[1]  D. Bers,et al.  Novel Epac fluorescent ligand reveals distinct Epac1 vs. Epac2 distribution and function in cardiomyocytes , 2015, Proceedings of the National Academy of Sciences.

[2]  P. Hotez,et al.  Global economic burden of Chagas disease: a computational simulation model. , 2013, The Lancet. Infectious diseases.

[3]  Xiaodong Cheng,et al.  A Novel EPAC-Specific Inhibitor Suppresses Pancreatic Cancer Cell Migration and Invasion , 2013, Molecular Pharmacology.

[4]  N. Flavahan,et al.  Cyclic AMP-Rap1A signaling activates RhoA to induce α(2c)-adrenoceptor translocation to the cell surface of microvascular smooth muscle cells. , 2012, American journal of physiology. Cell physiology.

[5]  D. Hochbaum,et al.  Radixin Assembles cAMP Effectors Epac and PKA into a Functional cAMP Compartment , 2010, The Journal of Biological Chemistry.

[6]  J. Bos,et al.  Spatial Regulation of Cyclic AMP-Epac1 Signaling in Cell Adhesion by ERM Proteins , 2010, Molecular and Cellular Biology.

[7]  T. Shibasaki,et al.  Roles of cAMP signalling in insulin granule exocytosis , 2009, Diabetes, obesity & metabolism.

[8]  Sheng Li,et al.  Phosphorylation-induced Conformational Changes in Rap1b , 2009, The Journal of Biological Chemistry.

[9]  Alberto Darszon,et al.  Epac Activates the Small G Proteins Rap1 and Rab3A to Achieve Exocytosis* , 2009, The Journal of Biological Chemistry.

[10]  J. Fredberg,et al.  Modulation of host cell mechanics by Trypanosoma cruzi , 2009, Journal of cellular physiology.

[11]  Xuequn Chen,et al.  Rap1 Activation Plays a Regulatory Role in Pancreatic Amylase Secretion* , 2008, Journal of Biological Chemistry.

[12]  D. Hochbaum,et al.  Epac, in Synergy with cAMP-dependent Protein Kinase (PKA), Is Required for cAMP-mediated Mitogenesis* , 2008, Journal of Biological Chemistry.

[13]  A. Lochner,et al.  The many faces of H89: a review. , 2006, Cardiovascular drug reviews.

[14]  P. Stork,et al.  Rap1-Mediated Activation of Extracellular Signal-Regulated Kinases by Cyclic AMP Is Dependent on the Mode of Rap1 Activation , 2006, Molecular and Cellular Biology.

[15]  T. Shibasaki,et al.  PKA-dependent and PKA-independent pathways for cAMP-regulated exocytosis. , 2005, Physiological reviews.

[16]  B. Burleigh,et al.  Host cell actin polymerization is required for cellular retention of Trypanosoma cruzi and early association with endosomal/lysosomal compartments , 2004, Cellular microbiology.

[17]  I. Martinez,et al.  cAMP Regulates Ca2+-dependent Exocytosis of Lysosomes and Lysosome-mediated Cell Invasion by Trypanosomes* , 1999, The Journal of Biological Chemistry.

[18]  N. Andrews.  Lysosome recruitment during host cell invasion by Trypanosoma cruzi. , 1995, Trends in cell biology.

[19]  M. Zerial,et al.  Association of Rap1a and Rap1b proteins with late endocytic/phagocytic compartments and Rap2a with the Golgi complex. , 1994, Journal of cell science.