TLP-mediated global transcriptional repression after double-strand DNA breaks slows down DNA repair and induces apoptosis

[1]  Fan Zhang,et al.  Regulation of DNA double-strand break repair pathway choice: a new focus on 53BP1 , 2021, Journal of Zhejiang University-SCIENCE B.

[2]  D. Gilmour,et al.  A sequence-specific core promoter-binding transcription factor recruits TRF2 to coordinately transcribe ribosomal protein genes , 2017, Nucleic acids research.

[3]  G. Legube,et al.  Transcription-Coupled DNA Double-Strand Break Repair: Active Genes Need Special Care. , 2017, Journal of molecular biology.

[4]  Hidefumi Suzuki,et al.  TBP-like Protein (TLP) Disrupts the p53-MDM2 Interaction and Induces Long-lasting p53 Activation* , 2017, The Journal of Biological Chemistry.

[5]  A. Chakraborty,et al.  Classical non-homologous end-joining pathway utilizes nascent RNA for error-free double-strand break repair of transcribed genes , 2016, Nature Communications.

[6]  S. Nakajima,et al.  DNA damage during the G0/G1 phase triggers RNA-templated, Cockayne syndrome B-dependent homologous recombination , 2015, Proceedings of the National Academy of Sciences.

[7]  Hidefumi Suzuki,et al.  TBP-like protein (TLP) interferes with Taspase1-mediated processing of TFIIA and represses TATA box gene expression , 2015, Nucleic acids research.

[8]  A. Ui,et al.  Transcriptional elongation factor ENL phosphorylated by ATM recruits polycomb and switches off transcription for DSB repair. , 2015, Molecular cell.

[9]  G. Legube,et al.  DNA double strand break repair pathway choice: a chromatin based decision? , 2015, Nucleus.

[10]  T. Juven-Gershon,et al.  TRF2: TRansForming the view of general transcription factors , 2015, Transcription.

[11]  Hiroshi Kimura,et al.  Regulation of RNA polymerase II activation by histone acetylation in single living cells , 2014, Nature.

[12]  R. Shamir,et al.  Drosophila TRF2 is a preferential core promoter regulator , 2014, Genes & development.

[13]  Alex D. Herbert,et al.  Requirement for PBAF in Transcriptional Repression and Repair at DNA Breaks in Actively Transcribed Regions of Chromatin , 2014, Molecular cell.

[14]  F. Storici,et al.  Transcript RNA-templated DNA recombination and repair , 2014, Nature.

[15]  Julia Zeitlinger,et al.  TRF2, but not TBP, mediates the transcription of ribosomal protein genes , 2014, Genes & development.

[16]  Zhaohui S. Qin,et al.  H2B ubiquitylation promotes RNA Pol II processivity via PAF1 and pTEFb. , 2014, Molecular cell.

[17]  Hidefumi Suzuki,et al.  Activity of the upstream TATA-less promoter of the p21Waf1/Cip1 gene depends on transcription factor IIA (TFIIA) in addition to TFIIA-reactive TBP-like protein , 2014, The FEBS journal.

[18]  S. Jackson,et al.  Transcriptionally active chromatin recruits homologous recombination at DNA double-strand breaks , 2014, Nature Structural &Molecular Biology.

[19]  Cheree Fitzgibbon,et al.  Chemo-sensitisation of HeLa cells to Etoposide by a Benzoxazine in the absence of DNA-PK inhibition , 2013, Investigational New Drugs.

[20]  F. Cecconi,et al.  New insights into the link between DNA damage and apoptosis. , 2013, Antioxidants & redox signaling.

[21]  Hidefumi Suzuki,et al.  TATA-binding Protein (TBP)-like Protein Is Required for p53-dependent Transcriptional Activation of Upstream Promoter of p21Waf1/Cip1 Gene , 2012, The Journal of Biological Chemistry.

[22]  S. Cocklin,et al.  Inhibition of homologous recombination in human cells by targeting RAD51 recombinase. , 2012, Journal of medicinal chemistry.

[23]  D. Stravopodis,et al.  Loss of CCDC6 Affects Cell Cycle through Impaired Intra-S-Phase Checkpoint Control , 2012, PloS one.

[24]  O. Bensaude,et al.  Inhibiting eukaryotic transcription. Which compound to choose? How to evaluate its activity? , 2011, Transcription.

[25]  Bernhard Kuster,et al.  Requirement of ATM-dependent monoubiquitylation of histone H2B for timely repair of DNA double-strand breaks. , 2011, Molecular cell.

[26]  D. Raleigh,et al.  Histone H2B ubiquitylation disrupts local and higher order chromatin compaction , 2010, Nature chemical biology.

[27]  R. Greenberg,et al.  ATM-Dependent Chromatin Changes Silence Transcription In cis to DNA Double-Strand Breaks , 2010, Cell.

[28]  C. Nam,et al.  Etoposide induces G2/M arrest and apoptosis in neural progenitor cells via DNA damage and an ATM/p53-related pathway. , 2010, Histology and histopathology.

[29]  I. Schonn,et al.  Cellular responses to etoposide: cell death despite cell cycle arrest and repair of DNA damage , 2010, Apoptosis.

[30]  A. Nakagawara,et al.  TATA-binding Protein (TBP)-like Protein Is Engaged in Etoposide-induced Apoptosis through Transcriptional Activation of Human TAp63 Gene* , 2009, The Journal of Biological Chemistry.

[31]  P. Hanawalt,et al.  Transcription-coupled DNA repair: two decades of progress and surprises , 2008, Nature Reviews Molecular Cell Biology.

[32]  R. Zimmer,et al.  High-resolution gene expression profiling for simultaneous kinetic parameter analysis of RNA synthesis and decay. , 2008, RNA.

[33]  Linda J. Kuo,et al.  γ-H2AX - A Novel Biomarker for DNA Double-strand Breaks , 2008 .

[34]  A. Horwitz,et al.  Multiple Mechanisms Contribute to Inhibit Transcription in Response to DNA Damage* , 2008, Journal of Biological Chemistry.

[35]  Wolf-Dietrich Heyer,et al.  Homologous recombination in DNA repair and DNA damage tolerance , 2008, Cell Research.

[36]  J. Nickoloff,et al.  Regulation of DNA double-strand break repair pathway choice , 2008, Cell Research.

[37]  N. Hernandez,et al.  On a roll for new TRF targets. , 2007, Genes & development.

[38]  C. Allis,et al.  Ubiquitylation of histone H2B controls RNA polymerase II transcription elongation independently of histone H3 methylation. , 2007, Genes & development.

[39]  Y. Suenaga,et al.  TATA-binding protein-related factor 2 is localized in the cytoplasm of mammalian cells and much of it migrates to the nucleus in response to genotoxic agents. , 2006, Molecules and cells.

[40]  R. Lothe,et al.  Differentiation of human embryonal carcinomas in vitro and in vivo reveals expression profiles relevant to normal development. , 2005, Cancer research.

[41]  D. Martincic,et al.  Topoisomerase II inhibitors. , 2005, Cancer chemotherapy and biological response modifiers.

[42]  Boris Zhivotovsky,et al.  DNA damage-induced apoptosis , 2004, Oncogene.

[43]  Hiroshi Handa,et al.  Specific Interaction with Transcription Factor IIA and Localization of the Mammalian TATA-binding Protein-like Protein (TLP/TRF2/TLF)* , 2004, Journal of Biological Chemistry.

[44]  J. Parvin,et al.  Elongation by RNA polymerase II on chromatin templates requires topoisomerase activity. , 2003, Nucleic acids research.

[45]  T. Nakadai,et al.  TATA-Binding Protein-Like Protein (TLP/TRF2/TLF) Negatively Regulates Cell Cycle Progression and Is Required for the Stress-Mediated G2 Checkpoint , 2003, Molecular and Cellular Biology.

[46]  K. Hande,et al.  Topoisomerase II inhibitors. , 2006, Cancer chemotherapy and biological response modifiers.

[47]  A. Berk.  TBP-like Factors Come into Focus , 2000, Cell.

[48]  P. Moore,et al.  A Human TATA Binding Protein-Related Protein with Altered DNA Binding Specificity Inhibits Transcription from Multiple Promoters and Activators , 1999, Molecular and Cellular Biology.

[49]  T. Tamura,et al.  Identification of a mouse TBP-like protein (TLP) distantly related to the drosophila TBP-related factor. , 1999, Nucleic acids research.