Real-time monitoring of receptor and G-protein interactions in living cells

[1]  S. Angers,et al.  Detection of beta 2-adrenergic receptor dimerization in living cells using bioluminescence resonance energy transfer (BRET). , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[2]  Anita Preininger,et al.  Insights into G protein structure, function, and regulation. , 2003, Endocrine reviews.

[3]  Jean-François Mercier,et al.  Quantitative Assessment of β1- and β2-Adrenergic Receptor Homo- and Heterodimerization by Bioluminescence Resonance Energy Transfer* , 2002, The Journal of Biological Chemistry.

[4]  P. Albert,et al.  G protein specificity: traffic direction required. , 2002, Cellular signalling.

[5]  A. Gilman,et al.  G proteins: transducers of receptor-generated signals. , 1987, Annual review of biochemistry.

[6]  B. Kinsella,et al.  Thromboxane A2 signalling in humans: a 'Tail' of two receptors. , 2001, Biochemical Society transactions.

[7]  M. Caron,et al.  Regulation of adenylyl cyclase-coupled beta-adrenergic receptors. , 1988, Annual review of cell biology.

[8]  P. Devreotes,et al.  Receptor-Mediated Activation of Heterotrimeric G-Proteins in Living Cells , 2001, Science.

[9]  M. Lohse,et al.  Measurement of the millisecond activation switch of G protein–coupled receptors in living cells , 2003, Nature Biotechnology.

[10]  R. Seifert,et al.  Molecular analysis of beta(2)-adrenoceptor coupling to G(s)-, G(i)-, and G(q)-proteins. , 2000, Molecular pharmacology.

[11]  Michel Bouvier,et al.  Oligomerization of G-protein-coupled transmitter receptors , 2001, Nature Reviews Neuroscience.

[12]  Xin Lin,et al.  Cell signalling through thromboxane A2 receptors. , 2004, Cellular signalling.

[13]  H. Bourne,et al.  How receptors talk to trimeric G proteins. , 1997, Current opinion in cell biology.

[14]  M. Rasenick,et al.  Real-time visualization of a fluorescent G(alpha)(s): dissociation of the activated G protein from plasma membrane. , 2002, Molecular pharmacology.

[15]  David P. Siderovski,et al.  Gβγ Isoforms Selectively Rescue Plasma Membrane Localization and Palmitoylation of Mutant Gαs and Gαq * , 2001, The Journal of Biological Chemistry.

[16]  P. Crespo,et al.  Dual effect of beta-adrenergic receptors on mitogen-activated protein kinase. Evidence for a beta gamma-dependent activation and a G alpha s-cAMP-mediated inhibition. , 1995, The Journal of biological chemistry.

[17]  M. Lohse,et al.  Gi protein activation in intact cells involves subunit rearrangement rather than dissociation , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[18]  A. Levitzki,et al.  G‐Protein Subunit Dissociation Is not an Integral Part of G‐Protein Action , 2002, Chembiochem : a European journal of chemical biology.

[19]  J. Venter,et al.  Site-directed mutagenesis and continuous expression of human beta-adrenergic receptors. Identification of a conserved aspartate residue involved in agonist binding and receptor activation. , 1988, The Journal of biological chemistry.

[20]  P. Crespo,et al.  Dual Effect of β-Adrenergic Receptors on Mitogen-activated Protein Kinase , 1995, The Journal of Biological Chemistry.

[21]  J. Bockaert,et al.  G protein-coupled receptors: dominant players in cell-cell communication. , 2002, International review of cytology.

[22]  P. Chidiac,et al.  Agonist-induced modulation of inverse agonist efficacy at the beta 2-adrenergic receptor. , 1996, Molecular pharmacology.

[23]  H. Kitano,et al.  A quantitative characterization of the yeast heterotrimeric G protein cycle , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[24]  D. Warner,et al.  Does subunit dissociation necessarily accompany the activation of all heterotrimeric G proteins? , 1997, Cellular signalling.

[25]  J. Northup,et al.  Independent and synergistic interaction of retinal G-protein subunits with bovine rhodopsin measured by surface plasmon resonance. , 2001, The Biochemical journal.

[26]  Jean-François Mercier,et al.  Quantitative assessment of beta 1- and beta 2-adrenergic receptor homo- and heterodimerization by bioluminescence resonance energy transfer. , 2002, The Journal of biological chemistry.

[27]  Sean M. Biggs,et al.  Techniques: GPCR assembly, pharmacology and screening by flow cytometry. , 2004, Trends in pharmacological sciences.

[28]  A. Miyawaki Visualization of the spatial and temporal dynamics of intracellular signaling. , 2003, Developmental cell.

[29]  D. Bylund,et al.  Desensitization of the alpha-2 adrenergic receptor in HT29 and opossum kidney cell lines. , 1990, The Journal of pharmacology and experimental therapeutics.

[30]  M. Bouvier,et al.  Allosteric effects of G protein overexpression on the binding of beta-adrenergic ligands with distinct inverse efficacies. , 2001, Molecular pharmacology.