Case report Laryngo-pharyngeal carcinoma in childhood

Laryngo-pharyngeal carcinoma is rare in children. We present two cases of squamous cell carcinoma of the laryngopharynx in children less than 15 years of age. Both patients presented with a prolonged history of symptoms and extensive disease at diagnosis. Early visualisation the vocal cords with flexible larygnoscopy is important in children presenting with symptoms suggestive of laryngeal pathology. Long-term complications of definitive local therapy for laryngopharyngeal carcinoma are important in young children. Evidence from studies in adult patients suggests that adjuvant chemotherapy may play a role in laryngeal preservation in a select group of patients. © 2001 Elsevier Science Ireland Ltd. All rights reserved.

[1]  D. Adelstein Induction chemotherapy in head and neck cancer. , 1999, Hematology/oncology clinics of North America.

[2]  A. Rapoport,et al.  Head and neck squamous cell carcinoma in childhood. , 1998, Medical and pediatric oncology.

[3]  W. Mcguirt,et al.  Laryngeal cancer in children and adolescents. , 1997, Otolaryngologic clinics of North America.

[4]  G. Healy,et al.  Malignant Laryngeal Tumors in Children: A 15-Year Experience with Four Patients , 1994, The Annals of otology, rhinology, and laryngology.

[5]  A. Schneider,et al.  Laryngeal carcinoma in a 12-year-old child. Association with human papillomavirus 18 and 33. , 1994, Archives of otolaryngology--head & neck surgery.

[6]  C. Jacobs,et al.  Chemotherapy for recurrent and metastatic head and neck cancer. , 1991, Hematology/oncology clinics of North America.

[7]  K. Bove,et al.  Carcinoma of the larynx in a child. , 1987, International journal of pediatric otorhinolaryngology.

[8]  N. Laurian,et al.  Laryngeal carcinoma in childhood. Report of a case and review of the literature , 1984, The Laryngoscope.

[9]  H. Dedo,et al.  Carcinoma of the larynx in childhood , 1980, Cancer.

[10]  P. Meyer-Breiting,et al.  Tumours of the Larynx , 1988, Springer Berlin Heidelberg.