Feasibility of dual-energy CT in the arterial phase: Imaging after endovascular aortic repair.

OBJECTIVE The purpose of this study was to investigate replacing unenhanced and arterial single-energy CT acquisitions after endovascular aneurysm repair with one dual-energy CT arterial acquisition. SUBJECTS AND METHODS Thirty patients underwent arterial dual-energy CT (80 and 140 kVp) and venous single-energy CT (120 kVp) after endovascular aneurysm repair, and the radiation doses were compared with those of a standard triple-phase protocol. Both virtual unenhanced and arterial images were generated with dual-energy CT. Images were reviewed clinically for detection of endoleaks and evaluation of stent and calcium appearance. The aortic luminal attenuation on virtual unenhanced CT images was compared with that on previously acquired true unenhanced images. Virtual unenhanced, arterial, and venous images were compared for thrombus attenuation. Single-energy CT and dual-energy CT images were compared for noise. RESULTS Replacement of two (unenhanced, arterial) of three single-energy CT acquisitions with one dual-energy CT acquisition resulted in 31% radiation dose savings. All images were clinically interpretable. Thoracic (32 +/- 2 vs 35 +/- 4 HU) and abdominal (30 +/- 3 vs 35 +/- 5 HU) aortic attenuation was similar on virtual unenhanced and true unenhanced images. Thrombus attenuation was similar on virtual unenhanced (32 +/- 6 HU), arterial phase (33 +/- 7 HU), and venous phase (34 +/- 6 HU) images. Decreased stent and calcium attenuation was observed at some locations on virtual unenhanced images. Noise in the thoracic (10 +/- 1 HU) and abdominal (12 +/- 2 HU) aorta was lower on virtual unenhanced images than on true unenhanced images (13 +/- 4 HU, 19 +/- 5 HU). Noise was comparable for dual-energy and single-energy CT (thorax, 16 +/- 2 vs 13 +/- 2 HU; abdomen, 21 +/- 3 vs 23 +/- 5 HU). CONCLUSION Virtual unenhanced and arterial phase images derived from dual-energy CT can replace true unenhanced and arterial phase single-energy CT images in follow-up after endovascular aneurysm repair (except immediately after the procedure), providing comparable diagnostic information with substantial dose savings.

[1]  K. Stierstorfer,et al.  Technical principles of dual source CT. , 2008, European journal of radiology.

[2]  R. Carmi,et al.  Material separation with dual-layer CT , 2005, IEEE Nuclear Science Symposium Conference Record, 2005.

[3]  E. Fishman,et al.  Thoracic aortic stent-grafts: utility of multidetector CT for pre- and postprocedure evaluation. , 2008, Radiographics : a review publication of the Radiological Society of North America, Inc.

[4]  E. Halpern,et al.  Attenuation of acute and chronic pulmonary emboli. , 2005, Radiology.

[5]  J. Hellinger Endovascular repair of thoracic and abdominal aortic aneurysms: pre- and postprocedural imaging. , 2005, Techniques in vascular and interventional radiology.

[6]  Borut Marincek,et al.  Endoleaks after endovascular abdominal aortic aneurysm repair: detection with dual-energy dual-source CT. , 2008, Radiology.

[7]  M. Macari,et al.  Dual energy CT: preliminary observations and potential clinical applications in the abdomen , 2008, European Radiology.

[8]  M. Reiser,et al.  Material differentiation by dual energy CT: initial experience , 2007, European Radiology.

[9]  D. C. Brewster,et al.  Endovascular repair of abdominal aortic aneurysms: current status and future directions. , 2000, AJR. American journal of roentgenology.

[10]  A. James O'Malley,et al.  Endovascular versus open repair of abdominal aortic aneurysms in the Medicare population , 2008 .

[11]  B. Sundaram,et al.  CT findings following thoracic aortic surgery. , 2007, Radiographics : a review publication of the Radiological Society of North America, Inc.

[12]  Aortic Endograft Surveillance: Use of Fast-Switch kVp Dual-Energy Computed Tomography With Virtual Noncontrast Imaging , 2011, Journal of computer assisted tomography.

[13]  M. Macari,et al.  Abdominal aortic aneurysm: can the arterial phase at CT evaluation after endovascular repair be eliminated to reduce radiation dose? , 2006, Radiology.

[14]  D. Sin,et al.  Estimation of cancer mortality associated with repetitive computed tomography scanning. , 2006, American journal of respiratory and critical care medicine.

[15]  Gianfranco Chiari,et al.  Clinical Usefulness of Computed Tomography Study Without Contrast Injection in the Evaluation of Acute Pulmonary Embolism , 2005, Journal of computer assisted tomography.

[16]  William H. Judy,et al.  The Measurement, Reporting, and Management of Radiation Dose in CT , 2008 .

[17]  Hersh Chandarana,et al.  Abdominal aorta: evaluation with dual-source dual-energy multidetector CT after endovascular repair of aneurysms--initial observations. , 2008, Radiology.

[18]  V. Duddalwar,et al.  Multislice CT angiography: a practical guide to CT angiography in vascular imaging and intervention. , 2004, The British journal of radiology.

[19]  L. Bonomo,et al.  Multidetector CT in abdominal aortic aneurysm treated with endovascular repair: are unenhanced and delayed phase enhanced images effective for endoleak detection? , 2006, Radiology.

[20]  D. Brenner,et al.  Computed tomography--an increasing source of radiation exposure. , 2007, The New England journal of medicine.

[21]  Janet T Powell,et al.  Endovascular repair of abdominal aortic aneurysm. , 2008, The New England journal of medicine.

[22]  David J Brenner,et al.  Estimated radiation risks potentially associated with full-body CT screening. , 2004, Radiology.

[23]  N. Fearnot,et al.  Zenith abdominal aortic aneurysm endovascular graft. , 2008, Journal of vascular surgery.

[24]  K. Stierstorfer,et al.  First performance evaluation of a dual-source CT (DSCT) system , 2006, European Radiology.