Medical Cannabis and Its Efficacy/Effectiveness for the Treatment of Low-Back Pain: a Systematic Review.

[1]  S. Klarenbach,et al.  Gaps in evidence for the use of medically authorized cannabis: Ontario and Alberta, Canada , 2021, Harm Reduction Journal.

[2]  A. Wong,et al.  The CANBACK trial: a randomised, controlled clinical trial of oral cannabidiol for people presenting to the emergency department with acute low back pain , 2021, The Medical journal of Australia.

[3]  S. Klarenbach,et al.  Opioid use in medical cannabis authorization adult patients from 2013 to 2018: Alberta, Canada , 2021, BMC Public Health.

[4]  M. Kogan,et al.  The intersection between integrative medicine and neuropathic pain: A case report. , 2021, Explore.

[5]  G. M. Allan,et al.  PEER systematic review of randomized controlled trials , 2021, Canadian Family Physician Médecin de famille canadien.

[6]  Z. Walsh,et al.  Cannabis Significantly Reduces the Use of Prescription Opioids and Improves Quality of Life in Authorized Patients: Results of a Large Prospective Study. , 2020, Pain medicine.

[7]  E. Mayo-Wilson,et al.  PRISMA 2020 explanation and elaboration: updated guidance and exemplars for reporting systematic reviews , 2020, BMJ.

[8]  F. Shofer,et al.  The Impact of Medical Cannabis on Intermittent and Chronic Opioid Users with Back Pain: How Cannabis Diminished Prescription Opioid Usage. , 2020, Cannabis and cannabinoid research.

[9]  O. Viswanath,et al.  Cannabis Use in Hospitalized Patients with Chronic Pain , 2020, Advances in Therapy.

[10]  I. Sohanpal,et al.  Medical Cannabis for the Management of Pain and Quality of Life in Chronic Pain Patients: A Prospective Observational Study. , 2020, Pain medicine.

[11]  A. Kaye,et al.  Cannabidiol (CBD) as a treatment of acute and chronic back pain: A case series and literature review. , 2020, Journal of opioid management.

[12]  B. Okusanya,et al.  Medical cannabis for the reduction of opioid dosage in the treatment of non-cancer chronic pain: a systematic review , 2020, Systematic Reviews.

[13]  N. S. Miller,et al.  A Review of Cases of Marijuana and Violence , 2020, International journal of environmental research and public health.

[14]  E. Romero-Sandoval,et al.  Cannabinoids in the Treatment of Back Pain. , 2020, Neurosurgery.

[15]  Jaspal R Singh,et al.  Cannabis Use and Low-Back Pain: A Systematic Review. , 2020, Cannabis and cannabinoid research.

[16]  M. Z. Hossain,et al.  Targeting Peripherally Restricted Cannabinoid Receptor 1, Cannabinoid Receptor 2, and Endocannabinoid-Degrading Enzymes for the Treatment of Neuropathic Pain Including Neuropathic Orofacial Pain , 2020, International journal of molecular sciences.

[17]  I. Arévalo-Rodriguez,et al.  Therapeutic use of cannabis and cannabinoids: an evidence mapping and appraisal of systematic reviews , 2020, BMC Complementary Medicine and Therapies.

[18]  A. Barry,et al.  Treatment of chronic noncancer pain in patients on opioid therapy in primary care: A retrospective cohort study , 2020, Canadian pharmacists journal : CPJ = Revue des pharmaciens du Canada : RPC.

[19]  S. Kanji,et al.  Benefits and harms of medical cannabis: a scoping review of systematic reviews , 2019, Systematic reviews.

[20]  M. Hall,et al.  The Opioid Crisis and the Future of Addiction and Pain Therapeutics , 2019, The Journal of Pharmacology and Experimental Therapeutics.

[21]  Michiel R de Boer,et al.  Benefits and harms of spinal manipulative therapy for the treatment of chronic low back pain: systematic review and meta-analysis of randomised controlled trials , 2019, BMJ.

[22]  D. Berlau,et al.  Perspectives on cannabis as a substitute for opioid analgesics. , 2019, Pain management.

[23]  E. Spackman,et al.  The adverse health effects and harms related to marijuana use: an overview review. , 2018, CMAJ open.

[24]  Lisa Belzak,et al.  The opioid crisis in Canada: a national perspective. , 2018, Health promotion and chronic disease prevention in Canada : research, policy and practice.

[25]  B. Martin,et al.  Impact of Medical Marijuana Legalization on Opioid Use, Chronic Opioid Use, and High-risk Opioid Use , 2018, Journal of General Internal Medicine.

[26]  K. Kroenke,et al.  Effect of Opioid vs Nonopioid Medications on Pain-Related Function in Patients With Chronic Back Pain or Hip or Knee Osteoarthritis Pain: The SPACE Randomized Clinical Trial , 2018, JAMA.

[27]  U. Kumar,et al.  Cannabinoid Receptors and the Endocannabinoid System: Signaling and Function in the Central Nervous System , 2018, International journal of molecular sciences.

[28]  Jacob M. Vigil,et al.  Associations between medical cannabis and prescription opioid use in chronic pain patients: A preliminary cohort study , 2017, PloS one.

[29]  R. Buchbinder,et al.  Diagnosis and management of low-back pain in primary care , 2017, Canadian Medical Association Journal.

[30]  J. Angst,et al.  Epidemiology of Back Pain in Young and Middle-Aged Adults: A Longitudinal Population Cohort Survey From Age 27-50 Years. , 2017, Psychosomatics.

[31]  R. Gunn,et al.  Expectancy of impairment attenuates marijuana-induced risk taking. , 2017, Drug and alcohol dependence.

[32]  Kylie A. Williams,et al.  Efficacy, Tolerability, and Dose-Dependent Effects of Opioid Analgesics for Low Back Pain: A Systematic Review and Meta-analysis. , 2016, JAMA internal medicine.

[33]  Viktoriya Magid,et al.  Cannabis Use Disorder in Adolescence. , 2016, Child and adolescent psychiatric clinics of North America.

[34]  S. Montella,et al.  Mechanisms of low back pain: a guide for diagnosis and therapy , 2016, F1000Research.

[35]  K. Mackie,et al.  An Introduction to the Endogenous Cannabinoid System , 2016, Biological Psychiatry.

[36]  R. Deyo,et al.  Opioids for low back pain , 2015, BMJ : British Medical Journal.

[37]  T. Smart,et al.  An efficient randomised, placebo-controlled clinical trial with the irreversible fatty acid amide hydrolase-1 inhibitor PF-04457845, which modulates endocannabinoids but fails to induce effective analgesia in patients with pain due to osteoarthritis of the knee , 2012, PAIN®.

[38]  T. Nurmikko,et al.  Sativex successfully treats neuropathic pain characterised by allodynia: A randomised, double-blind, placebo-controlled clinical trial , 2007, PAIN®.

[39]  R. Birch,et al.  Efficacy of two cannabis based medicinal extracts for relief of central neuropathic pain from brachial plexus avulsion: results of a randomised controlled trial , 2004, Pain.

[40]  W. Notcutt,et al.  Initial experiences with medicinal extracts of cannabis for chronic pain: Results from 34 ‘N of 1’ studies , 2004, Anaesthesia.

[41]  D. Wade,et al.  A preliminary controlled study to determine whether whole-plant cannabis extracts can improve intractable neurogenic symptoms , 2003, Clinical rehabilitation.

[42]  N. W. H. M. Dekkers.  PATIENTS AND METHODS , 1981 .