The redox stress hypothesis of aging.
暂无分享,去创建一个
[1] C. M. Child. Experimental control and modification of larval development in the sea urchin in relation to the axial gradients , 1916 .
[2] J. Loeb,et al. ON THE INFLUENCE OF FOOD AND TEMPERATURE UPON THE DURATION OF LIFE , 1917 .
[3] J. W. Macarthur,et al. Metabolic activity and duration of life. II. Metabolic rates and their relation to longevity in Daphnia magna , 1929 .
[4] D. Harman. Aging: a theory based on free radical and radiation chemistry. , 1956, Journal of gerontology.
[5] A. Clark,et al. Sensitivity to Oxygen During Postembryonic Development of the Wasp Habrobracon. , 1958, Science.
[6] C. Bassett,et al. The effects of varying oxygen concentrations on osteogenesis and embryonic cartilage in vitro. , 1967, The Journal of bone and joint surgery. American volume.
[7] C. Lints,et al. Respiration in Drosophila. II. Respiration in relation to age by wild, inbred and hybrid Drosophila melanogaster imagos. , 1968, Experimental gerontology.
[8] W. D. Kaplan,et al. A relation between longevity, metabolic rate, and activity in shaker mutants of Drosophila melanogaster. , 1970, Experimental gerontology.
[9] A. Caplan,et al. The control of muscle and cartilage development in the chick limb: the role of differential vascularization. , 1973, Journal of embryology and experimental morphology.
[10] R. S. Sohal,et al. Mating behavior, physical activity and aging in the housefly, Musca domestica. , 1973, Experimental gerontology.
[11] W. Pryor. CHAPTER 1 – The Role of Free Radical Reactions in Biological Systems , 1976 .
[12] W. Pryor. Free Radicals in Biology , 1976 .
[13] R. S. Sohal. Metabolic Rate and Life Span , 1976 .
[14] H. Atlan,et al. Effects of temperature on the life span, vitality and fine structure of Drosophila melanogaster , 1976, Mechanisms of Ageing and Development.
[15] I. Fridovich. The biology of oxygen radicals. , 1978, Science.
[16] C. Gryfe. Mechanical Concepts in Cardiovascular and Pulmonary Physiology. , 1978 .
[17] H. R. Massie,et al. Changes with age in copper and superoxide dismutase levels in brains of C57BL/6J mice , 1979, Mechanisms of Ageing and Development.
[18] C. P. Lyman,et al. Hibernation and longevity in the Turkish hamster Mesocricetus brandti. , 1981, Science.
[19] L. Partridge,et al. Sexual activity reduces lifespan of male fruitflies , 1981, Nature.
[20] R. G. Allen,et al. Life-lengthening effects of γ-radiation on the adult housefly, Musca domestica , 1982, Mechanisms of Ageing and Development.
[21] R. S. Sohal,et al. Relationship between metabolic rate, aging, lipid peroxidation, and fluorescent age pigment in milkweed bug, Oncopeltus fasciatus (Hemiptera). , 1982, Journal of gerontology.
[22] J. Nahmias,et al. Developmental and tissue-specific control of catalase expression in Drosophila melanogaster: correlations with rates of enzyme synthesis and degradation , 1983 .
[23] R. G. Allen,et al. Effects of diethyldithiocarbamate on life span, metabolic rate, superoxide dismutase, catalase, inorganic peroxides and glutathione in the adult male housefly, Musca domestica , 1984, Mechanisms of Ageing and Development.
[24] É. Le Bourg,et al. Spontaneous locomotor activity and life span. A test of the rate of living theory in Drosophila melanogaster. , 1984, Gerontology.
[25] B. Halliwell,et al. Oxygen toxicity, oxygen radicals, transition metals and disease. , 1984, The Biochemical journal.
[26] R. Cutler. CHAPTER 11 – Antioxidants, Aging, and Longevity , 1984 .
[27] E. Cadenas,et al. Oxidative stress: damage to intact cells and organs. , 1985, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.
[28] G. Phillips,et al. Effect of oxygen on morphogenesis and polypeptide expression by Mucor racemosus , 1985, Journal of bacteriology.
[29] B. Halliwell,et al. Free radicals in biology and medicine , 1985 .
[30] R. G. Allen,et al. Alterations in superoxide dismutase, glutathione, and peroxides in the plasmodial slime mold Physarum polycephalum during differentiation , 1985, Journal of cellular physiology.
[31] R. G. Allen,et al. Involvement of Glutathione in the Differentiation of the Slime Mold Physarum polycephalum , 1985, Development, growth & differentiation.
[32] A. Rivett,et al. Preferential degradation of the oxidatively modified form of glutamine synthetase by intracellular mammalian proteases. , 1985, The Journal of biological chemistry.
[33] H. Sies. Biochemistry of oxidative stress , 1986 .
[34] R. S. Sohal. The Rate of Living Theory: A Contemporary Interpretation , 1986 .
[35] R. G. Allen,et al. Oxygen free radicals play a role in cellular differentiation: an hypothesis. , 1986, Journal of free radicals in biology & medicine.
[36] R. S. Sohal,et al. Effects of ambient temperature on free radical generation, antioxidant defenses and life span in the adult housefly, Musca domestica , 1987, Experimental Gerontology.
[37] R. S. Sohal,et al. Age-related changes in the redox status of the housefly, Musca domestica. , 1987, Archives of gerontology and geriatrics.
[38] S. W. Lin,et al. Protein damage and degradation by oxygen radicals. IV. Degradation of denatured protein. , 1987, The Journal of biological chemistry.
[39] T. Johnson,et al. A mutation in the age-1 gene in Caenorhabditis elegans lengthens life and reduces hermaphrodite fertility. , 2002, Genetics.
[40] R. G. Allen,et al. Oxidative Stress and Cellular Differentiation , 1988, Annals of the New York Academy of Sciences.
[41] E. Stadtman. Biochemical markers of aging , 1988, Experimental Gerontology.
[42] R. G. Allen,et al. Superoxide dismutase induces differentiation in microplasmodia of the slime mold Physarum polycephalum. , 1988, Archives of biochemistry and biophysics.
[43] R. G. Allen,et al. Oxidative influence on development and differentiation: an overview of a free radical theory of development. , 1989, Free radical biology & medicine.
[44] E. Critchley. Interdisciplinary Topics in Gerontology Vol. 26: Innovative Trends in Psychogeriatrics , 1989 .
[45] R. S. Sohal,et al. Superoxide anion radical production in different animal species , 1989, Mechanisms of Ageing and Development.
[46] G. M. Tener,et al. Overexpression of Cu-Zn superoxide dismutase in Drosophila does not affect life-span. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[47] R. S. Sohal,et al. Relationship between antioxidant defenses and longevity in different mammalian species , 1990, Mechanisms of Ageing and Development.
[48] J. Viña. Glutathione : metabolism and physiological functions , 1990 .
[49] R. S. Sohal,et al. Hydrogen peroxide production by liver mitochondria in different species , 1990, Mechanisms of Ageing and Development.
[50] R. G. Allen,et al. Oxidative stress as a causal factor in differentiation and aging: a unifying hypothesis , 1990, Experimental Gerontology.
[51] A. Davison,et al. Mitochondrial mutations may increase oxidative stress: implications for carcinogenesis and aging? , 1990, Free radical biology & medicine.
[52] R. S. Sohal. Hydrogen peroxide production by mitochondria may be a biomarker of aging , 1991, Mechanisms of Ageing and Development.
[53] R. S. Sohal,et al. Hydrogen peroxide release by mitochondria increases during aging , 1991, Mechanisms of Ageing and Development.
[54] S. Austad,et al. Mammalian aging, metabolism, and ecology: evidence from the bats and marsupials. , 1991, Journal of gerontology.
[55] R. Cutler,et al. Human Longevity and Aging: Possible Role of Reactive Oxygen Species , 1991, Annals of the New York Academy of Sciences.
[56] R. S. Sohal,et al. Relationship between Antioxidants, Prooxidants, and the Aging Process a , 1992, Annals of the New York Academy of Sciences.
[57] R. S. Sohal,et al. Protein oxidative damage is associated with life expectancy of houseflies. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[58] C. Kenyon,et al. A C. elegans mutant that lives twice as long as wild type , 1993, Nature.
[59] R. S. Sohal. The free radical hypothesis of aging: An appraisal of the current status , 1993, Aging.
[60] R. S. Sohal,et al. Relationship between aging and susceptibility to protein oxidative damage. , 1993, Biochemical and biophysical research communications.
[61] R. S. Sohal,et al. Comparison of mitochondrial pro-oxidant generation and anti-oxidant defenses between rat and pigeon: possible basis of variation in longevity and metabolic potential , 1993, Mechanisms of Ageing and Development.
[62] R. S. Sohal,et al. Relationship between mitochondrial superoxide and hydrogen peroxide production and longevity of mammalian species. , 1993, Free radical biology & medicine.
[63] S. Cadenas,et al. Low mitochondrial free radical production per unit O2 consumption can explain the simultaneous presence of high longevity and high aerobic metabolic rate in birds. , 1994, Free radical research.
[64] R. S. Sohal,et al. Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster. , 1994, Science.
[65] R. S. Sohal,et al. Aging and protein oxidative damage , 1994, Mechanisms of Ageing and Development.
[66] R. S. Sohal,et al. Mitochondrial oxidative damage, hydrogen peroxide release, and aging. , 1994, Free radical biology & medicine.
[67] R. S. Sohal,et al. DNA oxidative damage and life expectancy in houseflies. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[68] R. S. Sohal,et al. Oxidative damage, mitochondrial oxidant generation and antioxidant defenses during aging and in response to food restriction in the mouse , 1994, Mechanisms of Ageing and Development.
[69] R. S. Sohal,et al. Mitochondrial superoxide and hydrogen peroxide generation, protein oxidative damage, and longevity in different species of flies. , 1995, Free radical biology & medicine.
[70] R. S. Sohal,et al. Simultaneous Overexpression of Copper- and Zinc-containing Superoxide Dismutase and Catalase Retards Age-related Oxidative Damage and Increases Metabolic Potential in Drosophila melanogaster(*) , 1995, The Journal of Biological Chemistry.
[71] B. Ames,et al. Mitochondrial decay in aging. , 1995, Biochimica et biophysica acta.
[72] R. S. Sohal,et al. Oxidative stress and aging in the Mongolian gerbil (Meriones unguiculatus) , 1995, Mechanisms of Ageing and Development.
[73] K. Davies. Oxidative stress: the paradox of aerobic life. , 1995, Biochemical Society symposium.
[74] R. S. Sohal,et al. Relationship between susceptibility to protein oxidation, aging, and maximum life span potential of different species , 1996, Experimental Gerontology.
[75] C. Kenyon. Ponce d'elegans: Genetic Quest for the Fountain of Youth , 1996, Cell.
[76] R. Weindruch,et al. Oxidative Stress, Caloric Restriction, and Aging , 1996, Science.
[77] C. Finch,et al. Genetics of aging. , 1997, Science.
[78] E. Stadtman,et al. Reactive oxygen-mediated protein oxidation in aging and disease. , 1997, Chemical research in toxicology.
[79] S. Goto,et al. Age-associated, oxidatively modified proteins: A critical evaluation , 1997, AGE.
[80] R. Weindruch,et al. Caloric Intake and Aging , 1997 .
[81] R. S. Sohal,et al. Mitochondrial Ubiquinone Homologues, Superoxide Radical Generation, and Longevity in Different Mammalian Species* , 1997, The Journal of Biological Chemistry.
[82] R. S. Sohal,et al. Oxidative damage during aging targets mitochondrial aconitase. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[83] R. S. Sohal,et al. Mitochondrial adenine nucleotide translocase is modified oxidatively during aging. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[84] J. Denu,et al. Specific and reversible inactivation of protein tyrosine phosphatases by hydrogen peroxide: evidence for a sulfenic acid intermediate and implications for redox regulation. , 1998, Biochemistry.
[85] Sohal Rs,et al. Role of oxidative stress in senescence. , 1998 .
[86] B. Ames,et al. The free radical theory of aging matures. , 1998, Physiological reviews.
[87] S. Benzer,et al. Extended life-span and stress resistance in the Drosophila mutant methuselah. , 1998, Science.
[88] G. Ruvkun,et al. An insulin-like signaling pathway affects both longevity and reproduction in Caenorhabditis elegans. , 1998, Genetics.
[89] A. Elia,et al. Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons , 1998, Nature Genetics.
[90] S. Ward,et al. Genetic and environmental conditions that increase longevity in Caenorhabditis elegans decrease metabolic rate. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[91] T. Kirkwood,et al. Positive correlation between mammalian life span and cellular resistance to stress. , 1999, Free radical biology & medicine.
[92] O. Griffith,et al. Biologic and pharmacologic regulation of mammalian glutathione synthesis. , 1999, Free radical biology & medicine.
[93] J. Tower,et al. FLP Recombinase-Mediated Induction of Cu/Zn-Superoxide Dismutase Transgene Expression Can Extend the Life Span of Adult Drosophila melanogaster Flies , 1999, Molecular and Cellular Biology.
[94] C. Winterbourn,et al. Reactivity of biologically important thiol compounds with superoxide and hydrogen peroxide. , 1999, Free radical biology & medicine.
[95] P. Klatt,et al. Regulation of protein function by S-glutathiolation in response to oxidative and nitrosative stress. , 2000, European journal of biochemistry.
[96] H. Gershon,et al. Paradigms in aging research: a critical review and assessment , 2000, Mechanisms of Ageing and Development.
[97] N. Holbrook,et al. Oxidants, oxidative stress and the biology of ageing , 2000, Nature.
[98] G. Lithgow,et al. Natural selection: Evolution of lifespan in C. elegans , 2000, Nature.
[99] Dean P. Jones,et al. Biomarkers of oxidative stress study: are plasma antioxidants markers of CCl(4) poisoning? , 2000, Free radical biology & medicine.
[100] R. S. Sohal,et al. 23 – Oxidative Stress as a Governing Factor in Physiological Aging , 2000 .
[101] R. S. Sohal,et al. Effects of aging and hyperoxia on oxidative damage to cytochrome c in the housefly, Musca domestica. , 2000, Free radical biology & medicine.
[102] M. Noble,et al. Redox state is a central modulator of the balance between self-renewal and differentiation in a dividing glial precursor cell. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[103] R. S. Sohal,et al. Current issues concerning the role of oxidative stress in aging: a perspective. , 2000, Results and problems in cell differentiation.
[104] R. S. Sohal,et al. Prevention of flight activity prolongs the life span of the housefly, Musca domestica, and attenuates the age-associated oxidative damamge to specific mitochondrial proteins. , 2000, Free radical biology & medicine.
[105] G. Smythe,et al. Measurements of protein carbonyls, ortho- and meta-tyrosine and oxidative phosphorylation complex activity in mitochondria from young and old rats. , 2001, Free radical biology & medicine.
[106] M. Tatar,et al. A Mutant Drosophila Insulin Receptor Homolog That Extends Life-Span and Impairs Neuroendocrine Function , 2001, Science.
[107] M. Rose. The Molecular Genetics of Aging. Siegfried Hekimi , 2001 .
[108] Freya Q. Schafer,et al. Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple. , 2001, Free radical biology & medicine.
[109] Zhongmao Guo,et al. Does oxidative damage to DNA increase with age? , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[110] E. Hafen,et al. Extension of Life-Span by Loss of CHICO, a Drosophila Insulin Receptor Substrate Protein , 2001, Science.
[111] N. Bowery. Current Opinion in Pharmacology: introduction to a new journal , 2001 .
[112] Raymond Y. N. Lee,et al. Regulation of C. elegans DAF-16 and its human ortholog FKHRL1 by the daf-2 insulin-like signaling pathway , 2001, Current Biology.
[113] C. Kenyon,et al. Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling , 2001, Nature Genetics.
[114] R. S. Sohal,et al. Mechanisms of aging: an appraisal of the oxidative stress hypothesis. , 2002, Free radical biology & medicine.
[115] R. S. Sohal. Role of oxidative stress and protein oxidation in the aging process. , 2002, Free radical biology & medicine.
[116] E. Stadtman. Importance of individuality in oxidative stress and aging. , 2002, Free radical biology & medicine.
[117] M. Noble,et al. Oligodendrocyte precursor cells from different brain regions express divergent properties consistent with the differing time courses of myelination in these regions. , 2002, Developmental biology.
[118] R. S. Sohal,et al. Phenotypic effects of familial amyotrophic lateral sclerosis mutant Sod alleles in transgenic Drosophila , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[119] R. S. Sohal. Oxidative stress hypothesis of aging. , 2002, Free radical biology & medicine.
[120] W. Dröge. Free radicals in the physiological control of cell function. , 2002, Physiological reviews.
[121] G. Barja. Rate of generation of oxidative stress-related damage and animal longevity. , 2002, Free radical biology & medicine.
[122] R. S. Sohal,et al. Ectopic expression of catalase in Drosophila mitochondria increases stress resistance but not longevity. , 2003, Free radical biology & medicine.
[123] R. S. Sohal,et al. Effects of age and caloric restriction on glutathione redox state in mice. , 2003, Free radical biology & medicine.
[124] T. Finkel. Oxidant signals and oxidative stress. , 2003, Current opinion in cell biology.
[125] H. Jasper,et al. JNK signaling confers tolerance to oxidative stress and extends lifespan in Drosophila. , 2003, Developmental cell.
[126] R. S. Sohal,et al. Does overexpression of Cu,Zn-SOD extend life span in Drosophila melanogaster? , 2003, Experimental Gerontology.
[127] P. Karplus,et al. Peroxiredoxin Evolution and the Regulation of Hydrogen Peroxide Signaling , 2003, Science.
[128] E. R. Taylor,et al. Interactions of mitochondrial thiols with nitric oxide. , 2003, Antioxidants & redox signaling.
[129] C. Epstein,et al. Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging. , 2003, Physiological genomics.
[130] W. Voorhies. Is life span extension in single gene long-lived Caenorhabditis elegans mutants due to hypometabolism? , 2003, Experimental Gerontology.
[131] A. Bokov,et al. The role of oxidative damage and stress in aging , 2004, Mechanisms of Ageing and Development.
[132] B. Friguet,et al. Age-related impairment of mitochondrial matrix aconitase and ATP-stimulated protease in rat liver and heart. , 2004, European journal of biochemistry.
[133] G. Barja. Aging in vertebrates, and the effect of caloric restriction: a mitochondrial free radical production–DNA damage mechanism? , 2004, Biological reviews of the Cambridge Philosophical Society.
[134] R. S. Sohal,et al. Free aminothiols, glutathione redox state and protein mixed disulphides in aging Drosophila melanogaster. , 2004, The Biochemical journal.
[135] B. Halliwell,et al. Establishing biomarkers of oxidative stress: the measurement of hydrogen peroxide in human urine. , 2004, Current medicinal chemistry.
[136] J. Tower,et al. Effects of simultaneous over-expression of Cu/ZnSOD and MnSOD on Drosophila melanogaster life span , 2004, Mechanisms of Ageing and Development.
[137] A. Saurin,et al. Widespread sulfenic acid formation in tissues in response to hydrogen peroxide , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[138] J. Curtsinger,et al. Testing the "rate of living" model: further evidence that longevity and metabolic rate are not inversely correlated in Drosophila melanogaster. , 2004, Journal of applied physiology.
[139] D. Templeton,et al. Oxidative stress inhibits MEKK1 by site-specific glutathionylation in the ATP-binding domain. , 2004, The Biochemical journal.
[140] B. Halliwell,et al. Measuring reactive species and oxidative damage in vivo and in cell culture: how should you do it and what do the results mean? , 2004, British journal of pharmacology.
[141] D. Pimentel,et al. S-Glutathiolation of Ras Mediates Redox-sensitive Signaling by Angiotensin II in Vascular Smooth Muscle Cells*[boxs] , 2004, Journal of Biological Chemistry.
[142] J. Stuart,et al. No evidence of mitochondrial respiratory dysfunction in OGG1-null mice deficient in removal of 8-oxodeoxyguanine from mitochondrial DNA. , 2005, Free radical biology & medicine.
[143] Stephen H. Thomas,et al. The longevity of Caenorhabditis elegans in soil , 2005, Biology Letters.
[144] M. Emond,et al. Extension of Murine Life Span by Overexpression of Catalase Targeted to Mitochondria , 2005, Science.
[145] R. S. Sohal,et al. In the Aging Housefly Aconitase Is the Only Citric Acid Cycle Enzyme to Decline Significantly , 2005, Journal of bioenergetics and biomembranes.
[146] H. Jasper,et al. JNK Extends Life Span and Limits Growth by Antagonizing Cellular and Organism-Wide Responses to Insulin Signaling , 2005, Cell.
[147] C. Kenyon. The Plasticity of Aging: Insights from Long-Lived Mutants , 2005, Cell.
[148] D. Toroser,et al. Overexpression of Glutamate-Cysteine Ligase Extends Life Span in Drosophila melanogaster* , 2005, Journal of Biological Chemistry.
[149] D. H. Thiel,et al. Biomarkers of oxidative stress study II: are oxidation products of lipids, proteins, and DNA markers of CCl4 poisoning? , 2005, Free radical biology & medicine.
[150] J. Vijg,et al. Genetics of longevity and aging. , 2005, Annual review of medicine.
[151] R. S. Sohal,et al. Enhanced catabolism of mitochondrial superoxide/hydrogen peroxide and aging in transgenic Drosophila. , 2005, The Biochemical journal.
[152] R. S. Sohal,et al. Aconitase and ATP synthase are targets of malondialdehyde modification and undergo an age-related decrease in activity in mouse heart mitochondria. , 2005, Biochemical and biophysical research communications.
[153] P. Maher. The effects of stress and aging on glutathione metabolism , 2005, Ageing Research Reviews.
[154] P. Ghezzi,et al. Thiol-disulfide balance: from the concept of oxidative stress to that of redox regulation. , 2005, Antioxidants & redox signaling.
[155] T. Hurd,et al. Glutathionylation of mitochondrial proteins. , 2005, Antioxidants & redox signaling.
[156] K. Houk,et al. Free radical biology and medicine: it's a gas, man! , 2006, American journal of physiology. Regulatory, integrative and comparative physiology.
[157] Dean P. Jones. Redefining oxidative stress. , 2006, Antioxidants & redox signaling.
[158] R. S. Sohal. Oxygen consumption and life span in the adult male housefly, Musca domestica , 2006, AGE.
[159] P. Maher. Redox control of neural function: background, mechanisms, and significance. , 2006, Antioxidants & redox signaling.
[160] E. Stadtman. Protein oxidation and aging. , 1992, Free radical research.
[161] R. S. Sohal,et al. Temperature-dependent trade-offs between longevity and fertility in the Drosophila mutant, methuselah , 2006, Experimental Gerontology.
[162] M. Rose,et al. Do longevity mutants always show trade-offs? , 2006, Experimental Gerontology.
[163] J. Stone,et al. Hydrogen peroxide: a signaling messenger. , 2006, Antioxidants & redox signaling.
[164] N. Leslie. The redox regulation of PI 3-kinase-dependent signaling. , 2006, Antioxidants & redox signaling.
[165] D. Toroser,et al. Aconitase is the main functional target of aging in the citric acid cycle of kidney mitochondria from mice , 2006, Mechanisms of Ageing and Development.
[166] S. Rhee,et al. H2O2, a Necessary Evil for Cell Signaling , 2006, Science.
[167] R. S. Sohal,et al. Comparison between the effects of aging and hyperoxia on glutathione redox state and protein mixed disulfides in Drosophila melanogaster , 2006, Mechanisms of Ageing and Development.
[168] P. Pelicci,et al. Hydrogen peroxide: a metabolic by-product or a common mediator of ageing signals? , 2007, Nature Reviews Molecular Cell Biology.
[169] F. Muller,et al. Trends in oxidative aging theories. , 2007, Free radical biology & medicine.
[170] D. Leibfritz,et al. Free radicals and antioxidants in normal physiological functions and human disease. , 2007, The international journal of biochemistry & cell biology.
[171] T. Johnson,et al. Relationship Between Mitochondrial Electron Transport Chain Dysfunction, Development, and Life Extension in Caenorhabditis elegans , 2007, PLoS biology.
[172] M. Gallogly,et al. Mechanisms of reversible protein glutathionylation in redox signaling and oxidative stress. , 2007, Current opinion in pharmacology.
[173] R. Pamplona,et al. Life and death: metabolic rate, membrane composition, and life span of animals. , 2007, Physiological reviews.
[174] D. Giustarini,et al. S-glutathionylation in protein redox regulation. , 2007, Free radical biology & medicine.
[175] L. Hayflick. Biological Aging Is No Longer an Unsolved Problem , 2007, Annals of the New York Academy of Sciences.
[176] R. Pamplona,et al. Highly resistant macromolecular components and low rate of generation of endogenous damage: Two key traits of longevity , 2007, Ageing Research Reviews.
[177] M. Toledano,et al. Disulfide Bond-mediated multimerization of Ask1 and its reduction by thioredoxin-1 regulate H(2)O(2)-induced c-Jun NH(2)-terminal kinase activation and apoptosis. , 2007, Molecular biology of the cell.
[178] F. Domann,et al. An epigenetic perspective on the free radical theory of development. , 2007, Free radical biology & medicine.
[179] A. J. Lambert,et al. Low rates of hydrogen peroxide production by isolated heart mitochondria associate with long maximum lifespan in vertebrate homeotherms , 2007, Aging cell.
[180] A. Dillin,et al. Mitochondria and aging: dilution is the solution. , 2007, Cell metabolism.
[181] Seung-Jae V. Lee,et al. Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans , 2007, Aging cell.
[182] M. Toledano,et al. ROS as signalling molecules: mechanisms that generate specificity in ROS homeostasis , 2007, Nature Reviews Molecular Cell Biology.
[183] Sabine S. Lange,et al. Stimulation of ES-cell-derived cardiomyogenesis and neonatal cardiac cell proliferation by reactive oxygen species and NADPH oxidase , 2007, Journal of Cell Science.
[184] K. Storey,et al. Tribute to P. L. Lutz: putting life on `pause' – molecular regulation of hypometabolism , 2007, Journal of Experimental Biology.
[185] G. Ruvkun,et al. Lifespan Regulation by Evolutionarily Conserved Genes Essential for Viability , 2007, PLoS genetics.
[186] Hannah J. Zhang,et al. An integrated view of oxidative stress in aging: basic mechanisms, functional effects, and pathological considerations. , 2007, American journal of physiology. Regulatory, integrative and comparative physiology.
[187] C. Winterbourn,et al. Thiol chemistry and specificity in redox signaling. , 2008, Free radical biology & medicine.
[188] R. S. Sohal,et al. Roles of Oxidative Stress in the Aging Process of Drosophila melanogaster , 2008 .
[189] R. S. Sohal,et al. Overexpression of Glucose-6-phosphate Dehydrogenase Extends the Life Span of Drosophila melanogaster* , 2008, Journal of Biological Chemistry.
[190] G. Nelson,et al. Mechanisms of Ageing and Development , 2008 .
[191] William B. Mair,et al. Aging and survival: the genetics of life span extension by dietary restriction. , 2008, Annual review of biochemistry.
[192] V. Rotello. Advanced drug delivery reviews theme issue. Preface. , 2008, Advanced drug delivery reviews.
[193] J. Stamler,et al. Redox-based regulation of signal transduction: principles, pitfalls, and promises. , 2008, Free radical biology & medicine.
[194] R. S. Sohal,et al. Pro-oxidant shift in glutathione redox state during aging. , 2008, Advanced drug delivery reviews.
[195] B. Halliwell,et al. The mitochondrial free radical theory of ageing--where do we stand? , 2008, Frontiers in bioscience : a journal and virtual library.
[196] Hongqiao Zhang,et al. The chemistry of cell signaling by reactive oxygen and nitrogen species and 4-hydroxynonenal. , 2008, Archives of biochemistry and biophysics.
[197] Dean P. Jones. Radical-free biology of oxidative stress. , 2008, American journal of physiology. Cell physiology.
[198] P. Mecocci,et al. Biomarkers of oxidative and nitrosative damage in Alzheimer's disease and mild cognitive impairment , 2009, Ageing Research Reviews.
[199] D. Giustarini,et al. Protein S-glutathionylation: a regulatory device from bacteria to humans. , 2009, Trends in biochemical sciences.
[200] Yael H. Edrey,et al. Protein stability and resistance to oxidative stress are determinants of longevity in the longest-living rodent, the naked mole-rat , 2009, Proceedings of the National Academy of Sciences.
[201] H. Forman. Signal transduction and reactive species. , 2009, Free radical biology & medicine.
[202] R. S. Sohal,et al. The Catalytic Subunit of Drosophila Glutamate-Cysteine Ligase Is a Nucleocytoplasmic Shuttling Protein* , 2009, Journal of Biological Chemistry.
[203] D. Gems,et al. Antioxidant defense and aging in C. elegans: Is the oxidative damage theory of aging wrong? , 2009, Cell cycle.
[204] U. Jakob,et al. Thiol-based redox switches in eukaryotic proteins. , 2009, Antioxidants & redox signaling.
[205] C. Epstein,et al. The overexpression of major antioxidant enzymes does not extend the lifespan of mice , 2008, Aging cell.
[206] Hongqiao Zhang,et al. Glutathione: overview of its protective roles, measurement, and biosynthesis. , 2009, Molecular aspects of medicine.
[207] Shelly C. Lu. Regulation of glutathione synthesis. , 2009, Molecular aspects of medicine.
[208] J. García,et al. Role of nuclear glutathione as a key regulator of cell proliferation. , 2009, Molecular aspects of medicine.
[209] R. S. Sohal,et al. Peroxiredoxin 5 confers protection against oxidative stress and apoptosis and also promotes longevity in Drosophila. , 2009, The Biochemical journal.
[210] A. Bokov,et al. Is the oxidative stress theory of aging dead? , 2009, Biochimica et biophysica acta.
[211] C. Epstein,et al. Overexpression of Mn superoxide dismutase does not increase life span in mice. , 2009, The journals of gerontology. Series A, Biological sciences and medical sciences.
[212] M. Gallogly,et al. Mechanistic and kinetic details of catalysis of thiol-disulfide exchange by glutaredoxins and potential mechanisms of regulation. , 2009, Antioxidants & redox signaling.
[213] Yun Shi,et al. Comparative studies of oxidative stress and mitochondrial function in aging. , 2010, Integrative and comparative biology.
[214] S. Powers,et al. Experimental guidelines for studies designed to investigate the impact of antioxidant supplementation on exercise performance. , 2010, International journal of sport nutrition and exercise metabolism.
[215] P. Withers,et al. Metabolic depression: a historical perspective. , 2010, Progress in molecular and subcellular biology.
[216] F. Muller,et al. Increased superoxide in vivo accelerates age‐associated muscle atrophy through mitochondrial dysfunction and neuromuscular junction degeneration , 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[217] R. S. Sohal,et al. Mitochondrial peroxiredoxins are critical for the maintenance of redox state and the survival of adult Drosophila. , 2010, Free radical biology & medicine.
[218] S. Hekimi,et al. Reactive Oxygen Species and Aging in Caenorhabditis elegans: Causal or Casual Relationship? , 2010, Antioxidants & redox signaling.
[219] J. Richards. Metabolic rate suppression as a mechanism for surviving environmental challenge in fish. , 2010, Progress in molecular and subcellular biology.
[220] R. S. Sohal,et al. Expression of multiple copies of mitochondrially targeted catalase or genomic Mn superoxide dismutase transgenes does not extend the life span of Drosophila melanogaster. , 2010, Free radical biology & medicine.
[221] S. Scheff,et al. Age-related changes in mitochondrial respiration and oxidative damage in the cerebral cortex of the Fischer 344 rat , 2010, Mechanisms of Ageing and Development.
[222] M. Mann,et al. Accurate Quantification of More Than 4000 Mouse Tissue Proteins Reveals Minimal Proteome Changes During Aging* , 2010, Molecular & Cellular Proteomics.
[223] H. Forman,et al. Signaling functions of reactive oxygen species. , 2010, Biochemistry.
[224] S. Oh,et al. Reactive oxygen species enhance differentiation of human embryonic stem cells into mesendodermal lineage , 2010, Experimental & Molecular Medicine.
[225] J. Cadet,et al. Oxidatively generated base damage to cellular DNA. , 2010, Free radical biology & medicine.
[226] J. Cadet,et al. Measurement of oxidatively generated base damage in cellular DNA and urine. , 2010, Free radical biology & medicine.
[227] S. Wright,et al. The Rate Of Living , 2011 .
[228] P. Zimniak. Relationship of electrophilic stress to aging. , 2011, Free radical biology & medicine.
[229] M. Jackson,et al. Age‐related changes in skeletal muscle reactive oxygen species generation and adaptive responses to reactive oxygen species , 2011, The Journal of physiology.
[230] J. Speakman,et al. The free‐radical damage theory: Accumulating evidence against a simple link of oxidative stress to ageing and lifespan , 2011, BioEssays : news and reviews in molecular, cellular and developmental biology.
[231] M. Wenk,et al. Mitochondrial Changes in Ageing Caenorhabditis elegans – What Do We Learn from Superoxide Dismutase Knockouts? , 2011, PloS one.
[232] E. Veal,et al. Hydrogen peroxide as a signaling molecule. , 2011, Antioxidants & redox signaling.
[233] M. Keshavan,et al. Antioxidants, redox signaling, and pathophysiology in schizophrenia: an integrative view. , 2011, Antioxidants & redox signaling.
[234] B. Burgering,et al. Forkhead box o as a sensor, mediator, and regulator of redox signaling. , 2011, Antioxidants & redox signaling.
[235] R. Brigelius-Flohé,et al. Basic principles and emerging concepts in the redox control of transcription factors. , 2011, Antioxidants & redox signaling.
[236] P. Karplus,et al. Cysteine-based Redox Switches in Enzymes , 2022 .
[237] A. Pyle,et al. Proliferative neural stem cells have high endogenous ROS levels that regulate self-renewal and neurogenesis in a PI3K/Akt-dependant manner. , 2011, Cell stem cell.
[238] M. Ristow,et al. Extending life span by increasing oxidative stress. , 2011, Free Radical Biology & Medicine.
[239] S. Petratos,et al. A Novel Unbiased Proteomic Approach to Detect the Reactivity of Cerebrospinal Fluid in Neurological Diseases* , 2011, Molecular & Cellular Proteomics.
[240] V. Gladyshev,et al. Thiol peroxidases mediate specific genome-wide regulation of gene expression in response to hydrogen peroxide , 2011, Proceedings of the National Academy of Sciences.