Implications of personalized medicine—perspective from a cancer center
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Fabrice Andre | F. André | V. Lazar | J. Soria | T. Tursz | L. Lacroix | Jean-Charles Soria | Vladimir Lazar | Ludovic Lacroix | Thomas Tursz
[1] Lee T. Sam,et al. Transcriptome Sequencing to Detect Gene Fusions in Cancer , 2009, Nature.
[2] J. Ptak,et al. High Frequency of Mutations of the PIK3CA Gene in Human Cancers , 2004, Science.
[3] Emerging Approaches in Molecular Profiling Affecting Oncology Drug Discovery , 2005 .
[4] N. Hanna,et al. EGF Receptor Gene Mutations Are Common in Lung Cancers From “Never Smokers” and Are Associated With Sensitivity of Tumors to Gefitinib and Erlotinib , 2006 .
[5] Patricia L. Harris,et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. , 2004, The New England journal of medicine.
[6] Des Powe,et al. FGFR1 amplification in breast carcinomas: a chromogenic in situ hybridisation analysis , 2007, Breast Cancer Research.
[7] Zhi Hu,et al. An integrative genomic and proteomic analysis of PIK3CA, PTEN, and AKT mutations in breast cancer. , 2008, Cancer research.
[8] T. Hubbard,et al. A census of human cancer genes , 2004, Nature Reviews Cancer.
[9] Lajos Pusztai,et al. Determination of oestrogen-receptor status and ERBB2 status of breast carcinoma: a gene-expression profiling study. , 2007, The Lancet. Oncology.
[10] F. Siannis,et al. Assessment of somatic k-RAS mutations as a mechanism associated with resistance to EGFR-targeted agents: a systematic review and meta-analysis of studies in advanced non-small-cell lung cancer and metastatic colorectal cancer. , 2008, The Lancet. Oncology.
[11] M. Ratain,et al. Clinical activity observed in a phase I dose escalation trial of an oral c-met and ALK inhibitor, PF-02341066. , 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[12] G. Parmigiani,et al. Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses , 2008, Science.
[13] R. Rosell,et al. Epidermal growth factor receptor tyrosine kinase inhibitors as first-line treatment in advanced nonsmall-cell lung cancer , 2010, Current opinion in oncology.
[14] R. Strausberg,et al. Whole-genome cancer analysis as an approach to deeper understanding of tumour biology , 2009, British Journal of Cancer.
[15] Amy E. Hawkins,et al. DNA sequencing of a cytogenetically normal acute myeloid leukemia genome , 2008, Nature.
[16] A. Kurian. BRCA1 and BRCA2 mutations across race and ethnicity: distribution and clinical implications , 2010, Current opinion in obstetrics & gynecology.
[17] Ryan D. Morin,et al. Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution , 2009, Nature.
[18] A. Emley,et al. RAS and RAF mutations in banal melanocytic aggregates contiguous with primary cutaneous melanoma: clues to melanomagenesis , 2009, The British journal of dermatology.
[19] E. Birney,et al. Patterns of somatic mutation in human cancer genomes , 2007, Nature.
[20] S. Gabriel,et al. EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy , 2004, Science.
[21] David I. Smith,et al. Tumor Transcriptome Sequencing Reveals Allelic Expression Imbalances Associated with Copy Number Alterations , 2010, PloS one.
[22] T. Mukohara,et al. Association between gain-of-function mutations in PIK3CA and resistance to HER2-targeted agents in HER2-amplified breast cancer cell lines. , 2010, Annals of oncology : official journal of the European Society for Medical Oncology.
[23] 안성민. Development of Personalized Tumor Biomarkers Using Massively Parallel Sequencing , 2011 .
[24] Michael Williams,et al. Overview of Drug Discovery and Development , 2006, Current protocols in pharmacology.
[25] J. Williams. Hedgehog signaling pathway as a target for therapeutic intervention in basal cell carcinoma. , 2003, Drug news & perspectives.
[26] S. Kobayashi,et al. Acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancers dependent on the epidermal growth factor receptor pathway. , 2009, Clinical lung cancer.
[27] Richard J. K. Taylor,et al. Long-term survival of women with breast cancer in New South Wales. , 2003, European journal of cancer.
[28] Philippe Dessen,et al. Molecular Characterization of Breast Cancer with High-Resolution Oligonucleotide Comparative Genomic Hybridization Array , 2009, Clinical Cancer Research.
[29] G. Hortobagyi,et al. Genomic predictors of pathologic response to preoperative chemotherapy for triple-negative and ER-positive/HER2-negative breast cancers , 2008 .
[30] S. Lippman,et al. Lung cancer. , 2008, The New England journal of medicine.
[31] C. Desmedt,et al. Gene expression predictors in breast cancer: current status, limitations and perspectives. , 2008, European journal of cancer.
[32] C. Perou,et al. TBCRC 001: EGFR inhibition with cetuximab added to carboplatin in metastatic triple-negative (basal-like) breast cancer , 2008 .
[33] A. Goldhirsch,et al. Clinical relevance of HER2 overexpression/amplification in patients with small tumor size and node-negative breast cancer. , 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[34] P. Jänne,et al. Mechanisms of Acquired Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Non–Small Cell Lung Cancer , 2008, Clinical Cancer Research.
[35] Brian J. Stevenson,et al. Transcriptome-guided characterization of genomic rearrangements in a breast cancer cell line , 2009, Proceedings of the National Academy of Sciences.
[36] J. Garcia-conde,et al. p95HER-2 Predicts Worse Outcome in Patients with HER-2-Positive Breast Cancer , 2006, Clinical Cancer Research.
[37] K. Flaherty,et al. Phase I study of PLX4032: Proof of concept for V600E BRAF mutation as a therapeutic target in human cancer. , 2016, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[38] M. Metzker. Sequencing technologies — the next generation , 2010, Nature Reviews Genetics.
[39] J. Rothberg,et al. Detection of oncogenic mutations in the EGFR gene in lung adenocarcinoma with differential sensitivity to EGFR tyrosine kinase inhibitors. , 2005, Cold Spring Harbor symposia on quantitative biology.