Toggle switches, pulses and oscillations are intrinsic properties of the Src activation/deactivation cycle
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[1] R. V. van Etten,et al. c-Abl Has High Intrinsic Tyrosine Kinase Activity That Is Stimulated by Mutation of the Src Homology 3 Domain and by Autophosphorylation at Two Distinct Regulatory Tyrosines* , 2000, The Journal of Biological Chemistry.
[2] J. Parsons,et al. Src family kinases, key regulators of signal transduction , 2004, Oncogene.
[3] K. Amrein,et al. Csk-mediated phosphorylation of substrates is regulated by substrate tyrosine phosphorylation. , 1998, Farmaco.
[4] Elliot L. Botvinick,et al. Visualizing the mechanical activation of Src , 2005, Nature.
[5] S. Fumagalli,et al. Requirement for Src family protein tyrosine kinases in G2 for fibroblast cell division. , 1995, Science.
[6] Boris N. Kholodenko,et al. Untangling the signalling wires , 2007, Nature Cell Biology.
[7] D. Shalloway,et al. Oncoprotein signalling and mitosis. , 1997, Cellular signalling.
[8] A. Elson,et al. Tyrosine Phosphatase-ε Activates Src and Supports the Transformed Phenotype of Neu-induced Mammary Tumor Cells* , 2003, The Journal of Biological Chemistry.
[9] Werner Dubitzky,et al. SRC family kinases and receptors: analysis of three activation mechanisms by dynamic systems modeling. , 2008, Biophysical journal.
[10] Paul Smolen,et al. Bistable MAP kinase activity: a plausible mechanism contributing to maintenance of late long-term potentiation. , 2008, American journal of physiology. Cell physiology.
[11] M. Frame,et al. Src in cancer: deregulation and consequences for cell behaviour. , 2002, Biochimica et biophysica acta.
[12] Tianhai Tian,et al. Plasma membrane nanoswitches generate high-fidelity Ras signal transduction , 2007, Nature Cell Biology.
[13] Carsten Schultz,et al. Live-Cell Imaging of Enzyme-Substrate Interaction Reveals Spatial Regulation of PTP1B , 2007, Science.
[14] Werner Dubitzky,et al. Deactivation of Src Family Kinases: Hypothesis Testing Using a Monte Carlo Sensitivity Analysis of Systems-Level Properties , 2007, J. Comput. Biol..
[15] E J Sass,et al. Characterization of cytosolic calcium oscillations induced by phenylephrine and vasopressin in single fura-2-loaded hepatocytes. , 1989, The Journal of biological chemistry.
[16] A. Tzafriri,et al. The total quasi-steady-state approximation is valid for reversible enzyme kinetics. , 2004, Journal of theoretical biology.
[17] S. Harrison,et al. Variation on an Src-like Theme , 2003, Cell.
[18] Y. Kalaidzidis,et al. RhoD regulates endosome dynamics through Diaphanous-related Formin and Src tyrosine kinase , 2003, Nature Cell Biology.
[19] Y. Kuznetsov,et al. Continuation techniques and interactive software for bifurcation analysis of ODEs and iterated maps: physics , 1993 .
[20] Wei Wang,et al. Effect of autophosphorylation on the catalytic and regulatory properties of protein tyrosine kinase Src. , 2002, Archives of biochemistry and biophysics.
[21] D. Kassel,et al. Correlation of the phosphorylation states of pp60c-src with tyrosine kinase activity: the intramolecular pY530-SH2 complex retains significant activity if Y419 is phosphorylated. , 1996, Biochemistry.
[22] B. Kholodenko,et al. Negative feedback and ultrasensitivity can bring about oscillations in the mitogen-activated protein kinase cascades. , 2000, European journal of biochemistry.
[23] Igor Goryanin,et al. Mathematical simulation and analysis of cellular metabolism and regulation , 1999, Bioinform..
[24] H. Hanafusa,et al. Detection of a Physical and Functional Interaction between Csk and Lck Which Involves the SH2 Domain of Csk and Is Mediated by Autophosphorylation of Lck on Tyrosine 394 (*) , 1996, The Journal of Biological Chemistry.
[25] R Thomas,et al. A complex control circuit. Regulation of immunity in temperate bacteriophages. , 1976, European journal of biochemistry.
[26] F. Das,et al. c-Src couples PI 3 kinase/Akt and MAPK signaling to PDGF-induced DNA synthesis in mesangial cells. , 2006, Cellular signalling.
[27] John J. Tyson,et al. Irreversible cell-cycle transitions are due to systems-level feedback , 2007, Nature Cell Biology.
[28] Giulio Superti-Furga,et al. Dynamic Coupling between the SH2 and SH3 Domains of c-Src and Hck Underlies Their Inactivation by C-Terminal Tyrosine Phosphorylation , 2001, Cell.
[29] G. Caron-Lormier,et al. Amplification and oscillations in the FAK/Src kinase system during integrin signaling. , 2005, Journal of theoretical biology.
[30] J. Hardwick,et al. The Activated Form of the Lck Tyrosine Protein Kinase in Cells Exposed to Hydrogen Peroxide Is Phosphorylated at Both Tyr-394 and Tyr-505* , 1997, The Journal of Biological Chemistry.
[31] R. Roskoski,et al. Src kinase regulation by phosphorylation and dephosphorylation. , 2005, Biochemical and biophysical research communications.
[32] V. Brunton,et al. The membrane targeting and spatial activation of Src, Yes and Fyn is influenced by palmitoylation and distinct RhoB/RhoD endosome requirements , 2007, Journal of Cell Science.
[33] Timothy J. Yeatman,et al. A renaissance for SRC , 2004, Nature Reviews Cancer.
[34] D. Shalloway,et al. A phosphotyrosine displacement mechanism for activation of Src by PTPα , 2000, The EMBO journal.
[35] Liang Qiao,et al. Bistability and Oscillations in the Huang-Ferrell Model of MAPK Signaling , 2007, PLoS Comput. Biol..
[36] M. T. Brown,et al. Regulation, substrates and functions of src. , 1996, Biochimica et biophysica acta.
[37] L. Segel,et al. Extending the quasi-steady state approximation by changing variables. , 1996, Bulletin of mathematical biology.
[38] Gongqin Sun,et al. Autophosphorylation of Src and Yes blocks their inactivation by Csk phosphorylation , 1998, Oncogene.
[39] S. Teitelbaum,et al. 1,25‐dihydroxyvitamin D3 regulates pp60c‐src activity and expression of a pp60c‐src activating phosphatase , 1997, Journal of cellular biochemistry.
[40] Marcel Mettlen,et al. Differential subcellular membrane recruitment of Src may specify its downstream signalling. , 2008, Experimental cell research.
[41] Werner Dubitzky,et al. Bistable switching and excitable behaviour in the activation of Src at mitosis , 2006, ISMB.
[42] Kai Simons,et al. Lipid rafts and signal transduction , 2000, Nature Reviews Molecular Cell Biology.
[43] S. Courtneidge,et al. The interplay between Src family kinases and receptor tyrosine kinases , 2004, Oncogene.
[44] W. Miller,et al. Cooperative activation of Src family kinases by SH3 and SH2 ligands. , 2007, Cancer letters.
[45] D. Kassel,et al. Characterization of pp60c-src tyrosine kinase activities using a continuous assay: autoactivation of the enzyme is an intermolecular autophosphorylation process. , 1995, Biochemistry.
[46] A. Brunati,et al. Spontaneous autophosphorylation of Lyn tyrosine kinase at both its activation segment and C-terminal tail confers altered substrate specificity. , 1998, Biochemistry.
[47] J. Corbin,et al. Autophosphorylation: a salient feature of protein kinases , 1993, Molecular and Cellular Biochemistry.
[48] T. Smithgall,et al. Autophosphorylation of the Fes Tyrosine Kinase , 1996, The Journal of Biological Chemistry.
[49] B. Kholodenko. Four-dimensional organization of protein kinase signaling cascades: the roles of diffusion, endocytosis and molecular motors , 2003, Journal of Experimental Biology.
[50] G. Martin. The hunting of the Src , 2001, Nature Reviews Molecular Cell Biology.
[51] B. Kholodenko. Cell-signalling dynamics in time and space , 2006, Nature Reviews Molecular Cell Biology.
[52] Shu Chien,et al. Determination of hierarchical relationship of Src and Rac at subcellular locations with FRET biosensors , 2008, Proceedings of the National Academy of Sciences.
[53] Sheila M. Thomas,et al. Cellular functions regulated by Src family kinases. , 1997, Annual review of cell and developmental biology.
[54] B. Kholodenko,et al. Signaling switches and bistability arising from multisite phosphorylation in protein kinase cascades , 2004, The Journal of cell biology.
[55] J. Ferrell. Self-perpetuating states in signal transduction: positive feedback, double-negative feedback and bistability. , 2002, Current opinion in cell biology.
[56] A. Elson,et al. Protein tyrosine phosphatase epsilon activates Yes and Fyn in Neu-induced mammary tumor cells. , 2004, Experimental cell research.
[57] Boris N Kholodenko,et al. Long-range signaling by phosphoprotein waves arising from bistability in protein kinase cascades , 2006, Molecular systems biology.
[58] H V Westerhoff,et al. Why cytoplasmic signalling proteins should be recruited to cell membranes. , 2000, Trends in cell biology.
[59] A. Brunati,et al. Autocatalytic tyrosine-phosphorylation of protein kinase CK2 alpha and alpha' subunits: implication of Tyr182. , 2001, The Biochemical journal.