Mental and Physical Well-Being Following Admission to Pediatric Intensive Care

Objective: To assess mental and physical well-being in school-aged children following admission to pediatric intensive care and to examine risk factors for worse outcome. Design: A prospective cohort study. Setting: Two PICUs. Subjects: A consecutive sample of 88 patients 5–16 years old (median age, 10.00 yr; interquartile range, 6.00–13.00 yr) admitted to PICU from 2007 to 2010 with septic illness, meningoencephalitis, or other critical illnesses were assessed a median of 5 months following discharge and outcomes compared with 100 healthy controls. Interventions: None. Measurements and Main Results: Parents completed questionnaires documenting child mental and physical well-being, including the Strengths and Difficulties Questionnaires, Chalder Fatigue Scale, and Child Sleep Habits Questionnaire. Children over 8 years completed the Impact of Event Scale -8. The children admitted to PICU scored worse on all measures in comparison with the healthy controls, with 20% scoring at risk for psychiatric disorder, 34% with high levels of post-traumatic stress symptoms, 38% at risk for fatigue disorder, and 80% scoring at risk for sleep disturbance. In the PICU group, multivariable regression analyses identified septic illness as an independent predictor of post-traumatic stress symptoms and family status, past child health problems, and PICU length of stay as predictors of reduced general mental well-being. Conclusions: Our findings indicate that a significant minority of school-aged children admitted to PICU are at risk for reduced mental and physical well-being in the short term. Symptoms of poor mental well-being were linked to both vulnerability factors and critical illness factors.

[1]  B. Sahakian,et al.  Neuropsychologic Function Three to Six Months Following Admission to the PICU With Meningoencephalitis, Sepsis, and Other Disorders: A Prospective Study of School-Aged Children* , 2013, Critical care medicine.

[2]  R. Viner,et al.  Outcomes of invasive meningococcal serogroup B disease in children and adolescents (MOSAIC): a case-control study , 2012, The Lancet Neurology.

[3]  F. Sennhauser,et al.  The mutual prospective influence of child and parental post-traumatic stress symptoms in pediatric patients. , 2012, Journal of child psychology and psychiatry, and allied disciplines.

[4]  G. Colville,et al.  Patterns of post-traumatic stress symptoms in families after paediatric intensive care , 2012, Intensive Care Medicine.

[5]  J. Gold,et al.  Posttraumatic stress disorder in children and their parents following admission to the pediatric intensive care unit: A review , 2012, Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies.

[6]  M. Garralda,et al.  The relationship between physical and mental health in children and adolescents , 2012 .

[7]  R. Riechelmann,et al.  Cancer-related fatigue: a practical review. , 2011, Annals of oncology : official journal of the European Society for Medical Oncology.

[8]  J. Dupond Fatigue in patients with rheumatic diseases. , 2011, Joint, bone, spine : revue du rhumatisme.

[9]  W. Katon,et al.  Psychiatric morbidity in pediatric critical illness survivors: a comprehensive review of the literature. , 2010, Archives of pediatrics & adolescent medicine.

[10]  D. Neasham,et al.  Longer-term psychiatric adjustment of children and parents after meningococcal disease , 2009, Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies.

[11]  F. Verhulst,et al.  Behavioural, emotional, and post-traumatic stress problems in children and adolescents, long term after septic shock caused by Neisseria meningitidis. , 2008, The British journal of clinical psychology.

[12]  W. D. de Carvalho,et al.  Pediatric delirium: a new diagnostic challenge of which to be aware. , 2008, Critical care medicine.

[13]  A. Bos,et al.  Posttraumatic stress disorder (PTSD) in children after paediatric intensive care treatment compared to children who survived a major fire disaster , 2008, Child and adolescent psychiatry and mental health.

[14]  S. Kerry,et al.  Children's factual and delusional memories of intensive care. , 2008, American journal of respiratory and critical care medicine.

[15]  B. Sahakian,et al.  Neuropsychological function in children following admission to paediatric intensive care: a pilot investigation , 2008, Intensive Care Medicine.

[16]  Adrian Angold,et al.  Traumatic events and posttraumatic stress in childhood. , 2007, Archives of general psychiatry.

[17]  T. Chalder,et al.  Practitioner review: chronic fatigue syndrome in childhood. , 2005, Journal of child psychology and psychiatry, and allied disciplines.

[18]  Sean Perrin,et al.  The Children's Revised Impact of Event Scale (CRIES): Validity as a Screening Instrument for PTSD , 2005, Behavioural and Cognitive Psychotherapy.

[19]  M. Garralda,et al.  Short-term psychiatric adjustment of children and their parents following meningococcal disease , 2005, Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies.

[20]  M. Garralda,et al.  Psychiatric outcome following paediatric intensive care unit (PICU) admission: a cohort study , 2004, Intensive Care Medicine.

[21]  D. Annane,et al.  The Neuropathology of Septic Shock , 2004, Brain pathology.

[22]  F. Shann,et al.  PIM2: a revised version of the Paediatric Index of Mortality , 2003, Intensive Care Medicine.

[23]  H. Meltzer,et al.  Mental health of children and adolescents in Great Britain , 2003, International review of psychiatry.

[24]  C. Johnston,et al.  Children’s Psychological Responses After Critical Illness and Exposure to Invasive Technology , 2002, Journal of developmental and behavioral pediatrics : JDBP.

[25]  S. Vergnaud,et al.  Psychiatric adjustment following meningococcal disease treated on a PICU , 2002, Intensive Care Medicine.

[26]  J. Owens,et al.  The Children's Sleep Habits Questionnaire (CSHQ): psychometric properties of a survey instrument for school-aged children. , 2000, Sleep.

[27]  S. Playfor,et al.  Recollection of children following intensive care , 2000, Archives of disease in childhood.

[28]  D Curran-Everett,et al.  Multiple comparisons: philosophies and illustrations. , 2000, American journal of physiology. Regulatory, integrative and comparative physiology.

[29]  R. Goodman The Strengths and Difficulties Questionnaire: a research note. , 1997, Journal of child psychology and psychiatry, and allied disciplines.

[30]  S. Wessely,et al.  Development of a fatigue scale. , 1993, Journal of psychosomatic research.

[31]  Jacob Cohen,et al.  A power primer. , 1992, Psychological bulletin.

[32]  A. Mack Traumatic Events and Posttraumatic Stress in Childhood , 2009 .

[33]  M. Garralda,et al.  Psychiatric adjustment in the year after meningococcal disease in childhood. , 2007, Journal of the American Academy of Child and Adolescent Psychiatry.

[34]  M. Kenward,et al.  An Introduction to the Bootstrap , 2007 .

[35]  R. A. Cureton-Lane,et al.  Sleep in the pediatric ICU: an empirical investigation. , 1997, American journal of critical care : an official publication, American Association of Critical-Care Nurses.

[36]  N. Corser Sleep of 1- and 2-year-old children in intensive care. , 1996, Issues in comprehensive pediatric nursing.