Neurodevelopmental outcome of bronchopulmonary dysplasia.

Children born very preterm are vulnerable for long-term cognitive, educational, and behavioral impairments; bronchopulmonary dysplasia (BPD) is an additional risk factor which exacerbates these problems. As a population, children with BPD exhibit low average IQ, academic difficulties, delayed speech and language development, visual-motor integration impairments, and behavior problems. Neuropsychological studies are sparse, but there is some evidence that children with BPD also display attention problems, memory and learning deficits, and executive dysfunction. BPD does not appear to be associated with a specific neuropsychological impairment but rather a global impairment.

[1]  M. Weichsel.  The therapeutic use of glucocorticoid hormones in the perinatal period: Potential neurological hazards , 1977, Annals of neurology.

[2]  H. Halliday,et al.  Behavioural adjustment in school of very low birthweight children. , 1997, Journal of child psychology and psychiatry, and allied disciplines.

[3]  K. Barrington.  The adverse neuro-developmental effects of postnatal steroids in the preterm infant: a systematic review of RCTs , 2001, BMC pediatrics.

[4]  N Marlow,et al.  Short-term memory and language outcomes after extreme prematurity at birth. , 1998, Journal of speech, language, and hearing research : JSLHR.

[5]  T. Keens,et al.  Clinically unsuspected hypoxia during sleep and feeding in infants with bronchopulmonary dysplasia. , 1988, Pediatrics.

[6]  J. Volpe.  Neurology of the Newborn , 1959, Major problems in clinical pediatrics.

[7]  H. Halliday,et al.  Perinatal predictors of ocular morbidity in school children who were very low birthweight. , 1993, Paediatric and perinatal epidemiology.

[8]  C. Leonard,et al.  Effect of medical and social risk factors on outcome of prematurity and very low birth weight. , 1990, The Journal of pediatrics.

[9]  S. Rosenthal,et al.  Psychological and developmental assessment : children with disabilities and chronic conditions , 2001 .

[10]  Stefano Vicari,et al.  Spatial working memory deficits in children at ages 3-4 who were low birth weight, preterm infants. , 2004, Neuropsychology.

[11]  B. Vohr,et al.  Neurodevelopmental and Growth Outcomes of Extremely Low Birth Weight Infants After Necrotizing Enterocolitis , 2005, Pediatrics.

[12]  G. Gioia,et al.  Assessment of executive functions in children with neurological impairment. , 2001 .

[13]  Martin H. Schmidt,et al.  Late sequelae of low birthweight: mediators of poor school performance at 11 years. , 2003, Developmental medicine and child neurology.

[14]  L. Doyle,et al.  Impact of Postnatal Systemic Corticosteroids on Mortality and Cerebral Palsy in Preterm Infants: Effect Modification by Risk for Chronic Lung Disease , 2005, Pediatrics.

[15]  D. Streiner,et al.  School-age outcomes in children who were extremely low birth weight from four international population-based cohorts. , 2003, Pediatrics.

[16]  B. Vohr,et al.  Neurodevelopmental Outcomes of Extremely Low Birth Weight Infants <32 Weeks’ Gestation Between 1993 and 1998 , 2005, Pediatrics.

[17]  Lynn T Singer,et al.  Cognitive and academic consequences of bronchopulmonary dysplasia and very low birth weight: 8-year-old outcomes. , 2003, Pediatrics.

[18]  L. Doyle.  Evaluation of neonatal intensive care for extremely low birth weight infants in Victoria over two decades: II. Efficiency. , 2004, Pediatrics.

[19]  J. Volpe,et al.  Movement disorder of premature infants with severe bronchopulmonary dysplasia: a new syndrome. , 1989, Pediatrics.

[20]  T. O'Shea,et al.  Randomized Placebo-controlled Trial of a 42-Day Tapering Course of Dexamethasone to Reduce the Duration of Ventilator Dependency in Very Low Birth Weight Infants , 1999, Pediatrics.

[21]  R. Kikinis,et al.  Quantitative magnetic resonance imaging of brain development in premature and mature newborns , 1998, Annals of neurology.

[22]  L. Doyle,et al.  Respiratory function at age 8–9 years in extremely low birthweight/very preterm children born in Victoria in 1991–1992 , 2006, Pediatric pulmonology.

[23]  Renate Meyer,et al.  Cognitive status, language attainment, and prereading skills of 6‐year‐old very preterm children and their peers: the Bavarian Longitudinal Study , 1999, Developmental medicine and child neurology.

[24]  A. Salvator,et al.  Speech and language outcomes of children with bronchopulmonary dysplasia. , 2002, Journal of communication disorders.

[25]  H. O'brodovich,et al.  Long-term outcome of preterm infants with respiratory disease. , 1987, Clinics in perinatology.

[26]  M. Durkin,et al.  Factors associated with microcephaly at school age in a very-low-birthweight population , 2003 .

[27]  L. Wright,et al.  NICHD Neonatal Research Network , 2002 .

[28]  Y. Rogers,et al.  Psychoeducational outcome at school age of preterm infants with bronchopulmonary dysplasia , 2004, Journal of paediatrics and child health.

[29]  H. Taeusch.  Glucocorticoid prophylaxis for respiratory distress syndrome: a review of potential toxicity. , 1975, The Journal of pediatrics.

[30]  Victorian Infant Collaborative.  Postnatal corticosteroids and sensorineural outcome at 5 years of age , 2000, Journal of paediatrics and child health.

[31]  N Marlow,et al.  Attention deficit hyperactivity disorders and other psychiatric outcomes in very low birthweight children at 12 years. , 1997, Journal of child psychology and psychiatry, and allied disciplines.

[32]  A. Fanaroff,et al.  Outcomes of children of extremely low birthweight and gestational age in the 1990s. , 2000, Seminars in neonatology : SN.

[33]  B. Vohr,et al.  School-age outcomes of very low birth weight infants in the indomethacin intraventricular hemorrhage prevention trial. , 2003, Pediatrics.

[34]  J. Fletcher,et al.  Longitudinal outcome for low birth weight infants: effects of intraventricular hemorrhage and bronchopulmonary dysplasia. , 1993, Journal of clinical and experimental neuropsychology.

[35]  N. Minich,et al.  Verbal Memory Deficits in Children with Less than 750 g Birth Weight , 2000, Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence.

[36]  K C Schneider,et al.  The Etiology and Outcome of Cerebral Ventriculomegaly at Term in Very Low Birth Weight Preterm Infants , 1999, Pediatrics.

[37]  A. Bhutta,et al.  Cognitive and behavioral outcomes of school-aged children who were born preterm: a meta-analysis. , 2002, JAMA.

[38]  L. Doyle,et al.  Neurobehavioral outcomes of school-age children born extremely low birth weight or very preterm in the 1990s. , 2003, JAMA.

[39]  P. Filipek,et al.  Long-term neuropsychological outcomes of very low birth weight: Associations with early risks for periventricular brain insults , 2004, Journal of the International Neuropsychological Society.

[40]  A. Zaritsky,et al.  Early postnatal dexamethasone treatment and increased incidence of cerebral palsy , 2000, Archives of disease in childhood. Fetal and neonatal edition.

[41]  L. Lilien,et al.  A longitudinal study of developmental outcome of infants with bronchopulmonary dysplasia and very low birth weight. , 1997, Pediatrics.

[42]  B. Lewis,et al.  Preschool Language Outcomes of Children With History of Bronchopulmonary Dysplasia and Very Low Birth Weight , 2001, Journal of developmental and behavioral pediatrics : JDBP.

[43]  D. Aram,et al.  Very-low-birthweight children and speech and language development. , 1991, Journal of speech and hearing research.

[44]  A. Orgill,et al.  Neonatal and neurodevelopmental significance of behaviour in very low birthweight children. , 1985, Early human development.

[45]  M. Hack,et al.  INCREASED RISK OF CEREBRAL PALSY AMONG VERY LOW‐BIRTHWEIGHT INFANTS WITH CHRONIC LUNG DISEASE , 1990, Developmental medicine and child neurology.

[46]  M. Whitfield,et al.  Developmental Coordination Disorder in Extremely Low Birth Weight Children at Nine Years , 2002, Journal of developmental and behavioral pediatrics : JDBP.

[47]  M. Cheang,et al.  Language development of very low birth weight infants and fullterm controls at 12 months of age. , 1990, Early human development.

[48]  R. Sapolsky.  Why Stress Is Bad for Your Brain , 1996, Science.

[49]  T. Yeh,et al.  Early dexamethasone therapy in preterm infants: a follow-up study. , 1998, Pediatrics.

[50]  B. Vohr,et al.  NEURODEVELOPMENTAL AND MEDICAL STATUS OF LOW‐BIRTHWEIGHT SURVIVORS OF BRONCHOPULMONARY DYSPLASIA AT 10 TO 12 YEARS OF AGE , 1991, Developmental medicine and child neurology.

[51]  M. Hack,et al.  Attention deficits in children with <750 gm birth weight. , 1998 .

[52]  N. Marlow,et al.  Cognitive and educational outcome of very‐low‐birthweight children in early adolescence , 1998, Developmental medicine and child neurology.

[53]  I. Wallace,et al.  Patterns of cognitive development in very low birth weight children during the first six years of life. , 1997, Pediatrics.

[54]  E. Goldson,et al.  Eight-year school performance, neurodevelopmental, and growth outcome of neonates with bronchopulmonary dysplasia: a comparative study. , 1992, Pediatrics.

[55]  P. Anderson.  Assessment and Development of Executive Function (EF) During Childhood , 2002, Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence.

[56]  B. Schmidt,et al.  Impact of bronchopulmonary dysplasia, brain injury, and severe retinopathy on the outcome of extremely low-birth-weight infants at 18 months: results from the trial of indomethacin prophylaxis in preterms. , 2003, JAMA.

[57]  B. Böhm,et al.  Cognitive development at 5.5 years of children with chronic lung disease of prematurity , 2003, Archives of disease in childhood. Fetal and neonatal edition.

[58]  N. Marlow,et al.  Neurologic and developmental disability at six years of age after extremely preterm birth. , 2005, The New England journal of medicine.

[59]  M. Isohanni,et al.  Schizophrenia as a long-term outcome of pregnancy, delivery, and perinatal complications: a 28-year follow-up of the 1966 north Finland general population birth cohort. , 1998, The American journal of psychiatry.

[60]  R. Dean,et al.  PERINATAL COMPLICATIONS AS PREDICTORS OF INFANTILE AUTISM , 2002, The International journal of neuroscience.

[61]  Y. Shyr,et al.  Cognitive performance at school age of very low birth weight infants with bronchopulmonary dysplasia. , 1999, Journal of developmental and behavioral pediatrics : JDBP.

[62]  D. J. Goldstein,et al.  Randomized Placebo-controlled Trial of a 42-Day Tapering Course of Dexamethasone to Reduce the Duration of Ventilator Dependency in Very Low Birth Weight Infants: Outcome of Study Participants at 1-Year Adjusted Age , 1999, Pediatrics.

[63]  Lex W. Doyle.  Neonatal intensive care at borderline viability--is it worth it? , 2004 .

[64]  S. Teplin,et al.  Very-Low-Birthweight Infants at Seven Years , 1998, Journal of learning disabilities.

[65]  R. Adams,et al.  Long-term visual pathology in children with significant perinatal complications , 2005 .

[66]  T. Senn,et al.  Executive Functions in Preschool Children Born Preterm: Application of Cognitive Neuroscience Paradigms , 2002, Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence.

[67]  W. Northway,et al.  Pulmonary disease following respirator therapy of hyaline-membrane disease. Bronchopulmonary dysplasia. , 1967, The New England journal of medicine.

[68]  B. Stoll,et al.  Neurodevelopmental Outcomes of Extremely Low Birth Weight Infants Exposed Prenatally to Dexamethasone Versus Betamethasone , 2008, Pediatrics.

[69]  Y. Rogers,et al.  Conductive hearing loss in preterm infants with bronchopulmonary dysplasia , 2001, Journal of paediatrics and child health.

[70]  N. Bayley.  Bayley Scales of Infant Development , 1999 .

[71]  L. Doyle,et al.  Executive functioning in school-aged children who were born very preterm or with extremely low birth weight in the 1990s. , 2004, Pediatrics.

[72]  J. Perlman,et al.  Neurobehavioral deficits in premature graduates of intensive care--potential medical and neonatal environmental risk factors. , 2001, Pediatrics.

[73]  D. J. Goldstein,et al.  OUTCOME AT 4 TO 5 YEARS OF ÂGE IN CHILDREN RECOVERED FROM NEONATAL CHRONIC LUNG DISEASE , 1996, Developmental medicine and child neurology.

[74]  C. Schatschneider,et al.  Predictors of Early School Age Outcomes in Very Low Birth Weight Children , 1998, Journal of developmental and behavioral pediatrics : JDBP.

[75]  E. Alvord,et al.  A Proposed Neuropathological Basis for Learning Disabilities in Children Born Prematurely , 1983, Developmental medicine and child neurology.

[76]  R. Grunau,et al.  Psychosocial and Academic Characteristics of Extremely Low Birth Weight (≤800 g) Adolescents Who Are Free of Major Impairment Compared With Term-Born Control Subjects , 2004, Pediatrics.

[77]  M. Walsh,et al.  The NICHD neonatal research network: changes in practice and outcomes during the first 15 years. , 2003, Seminars in perinatology.

[78]  N. Breslau,et al.  Low birth weight and neurocognitive status at six years of age , 1996, Biological Psychiatry.