Bioanalysis of recombinant proteins and antibodies by mass spectrometry.
暂无分享,去创建一个
[1] S. Kern,et al. Quality control of serum albumin depletion for proteomic analysis. , 2007, Clinical chemistry.
[2] Darryl B. Hardie,et al. Mass spectrometric quantitation of peptides and proteins using Stable Isotope Standards and Capture by Anti-Peptide Antibodies (SISCAPA). , 2004, Journal of proteome research.
[3] J. M. Beals,et al. In vivo deamidation characterization of monoclonal antibody by LC/MS/MS. , 2005, Analytical chemistry.
[4] C. G. Edmonds,et al. Tandem mass spectrometry of very large molecules. 2. Dissociation of multiply charged proline-containing proteins from electrospray ionization. , 1993, Analytical chemistry.
[5] Viswanath Devanarayan,et al. Recommendations on risk-based strategies for detection and characterization of antibodies against biotechnology products. , 2008, Journal of immunological methods.
[6] C. Massart,et al. Intermethod variability in TSH-receptor antibody measurement: implication for the diagnosis of Graves disease and for the follow-up of Graves ophthalmopathy. , 2009, Clinical chemistry.
[7] Eric M Gage,et al. Method development for the concentration determination of a protein in human plasma utilizing 96-well solid-phase extraction and liquid chromatography/tandem mass spectrometric detection. , 2003, Rapid communications in mass spectrometry : RCM.
[8] S. Gygi,et al. Absolute quantification of proteins and phosphoproteins from cell lysates by tandem MS , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[9] M. Berna,et al. Coupling immunoaffinity techniques with MS for quantitative analysis of low-abundance protein biomarkers , 2007, Expert review of proteomics.
[10] E. Varesio,et al. Ultra-fast quantitation of saquinavir in human plasma by matrix-assisted laser desorption/ionization and selected reaction monitoring mode detection. , 2008, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
[11] John Mark Carter,et al. Mass spectrometric detection of attomole amounts of the prion protein by nanoLC/MS/MS , 2007, Journal of the American Society for Mass Spectrometry.
[12] April S Y Wong,et al. Doping control analysis of insulin and its analogues in equine urine by liquid chromatography-tandem mass spectrometry. , 2008, Journal of chromatography. A.
[13] R. Hansen,et al. Antibody pharmacokinetics and pharmacodynamics. , 2004, Journal of pharmaceutical sciences.
[14] K. Duffin,et al. Online immunoaffinity liquid chromatography/tandem mass spectrometry determination of a type II collagen peptide biomarker in rat urine: Investigation of the impact of collision-induced dissociation fluctuation on peptide quantitation. , 2006, Analytical biochemistry.
[15] R. Nelson,et al. Quantitative mass spectrometric immunoassay of insulin like growth factor 1. , 2004, Journal of proteome research.
[16] Elucidation of peptide metabolism by on-line immunoaffinity liquid chromatography mass spectrometry. , 2000, Rapid communications in mass spectrometry : RCM.
[17] M. Stahl,et al. Selective quantitative bioanalysis of proteins in biological fluids by on-line immunoaffinity chromatography-protein digestion-liquid chromatography-mass spectrometry. , 2006, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
[18] E. De Pauw,et al. Development of an absolute quantification method targeting growth hormone biomarkers using liquid chromatography coupled to isotope dilution mass spectrometry. , 2007, Journal of chromatography. A.
[19] S. Swanson,et al. Detection of neutralizing anti-therapeutic protein antibodies in serum or plasma samples containing high levels of the therapeutic protein. , 2006, Journal of immunological methods.
[20] J. Tabet,et al. Approach to the determination of insulin-like-growth-factor-I (IGF-I) concentration in plasma by high-performance liquid chromatography-ion trap mass spectrometry: use of a deconvolution algorithm for the quantification of multiprotonated molecules in electrospray ionization. , 2001, The Analyst.
[21] R. Nelson,et al. Novel mass spectrometric immunoassays for the rapid structural characterization of plasma apolipoproteins Published, JLR Papers in Press, December 1, 2002. DOI 10.1194/jlr.D200034-JLR200 , 2003, Journal of Lipid Research.
[22] Werner Zolg,et al. Quantification of C‐reactive protein in the serum of patients with rheumatoid arthritis using multiple reaction monitoring mass spectrometry and 13C‐labeled peptide standards , 2004, Proteomics.
[23] B. Güttler,et al. Protein quantification by isotope dilution mass spectrometry of proteolytic fragments: cleavage rate and accuracy. , 2008, Analytical chemistry.
[24] H. R. Bergen,et al. On-line immunoaffinity-liquid chromatography-mass spectrometry for identification of amyloid disease markers in biological fluids. , 2003, Analytical chemistry.
[25] G. Doncel,et al. Biological and Technical Variables Affecting Immunoassay Recovery of Cytokines from Human Serum and Simulated Vaginal Fluid: A Multicenter Study , 2008, Analytical chemistry.
[26] K. Parker,et al. Multiplexed Protein Quantitation in Saccharomyces cerevisiae Using Amine-reactive Isobaric Tagging Reagents*S , 2004, Molecular & Cellular Proteomics.
[27] Darrell Ricke,et al. Absolute quantification of monoclonal antibodies in biofluids by liquid chromatography-tandem mass spectrometry. , 2008, Analytical chemistry.
[28] Tom Fiers,et al. Pilot study for the standardization of insulin immunoassays with isotope dilution liquid chromatography/tandem mass spectrometry. , 2007, Clinical Chemistry.
[29] Mark Brönstrup,et al. Absolute quantification strategies in proteomics based on mass spectrometry , 2004, Expert review of proteomics.
[30] C. Enjalbal,et al. New example of proline-induced fragmentation in electrospray ionization mass spectrometry of peptides. , 2002, Rapid communications in mass spectrometry : RCM.
[31] R. Sapin. Insulin immunoassays: fast approaching 50 years of existence and still calling for standardization. , 2007, Clinical chemistry.
[32] Eugen Koren,et al. An acid dissociation bridging ELISA for detection of antibodies directed against therapeutic proteins in the presence of antigen. , 2005, Journal of immunological methods.
[33] M. Maurel,et al. Evaluation of a peptide ELISA for the detection of rituximab in serum. , 2007, Journal of immunological methods.
[34] G. Nakamura,et al. Binding Protein-3-Selective Insulin-Like Growth Factor I Variants: Engineering, Biodistributions, and Clearance. , 2001, Endocrinology.
[35] O. Nemirovskiy,et al. Immunoaffinity liquid chromatography-tandem mass spectrometry detection of nitrotyrosine in biological fluids: development of a clinically translatable biomarker. , 2008, Analytical biochemistry.
[36] W Greg Miller,et al. Standardization of insulin immunoassays: report of the American Diabetes Association Workgroup. , 2007, Clinical chemistry.
[37] Jérôme Garin,et al. Protein Standard Absolute Quantification (PSAQ) for improved investigation of staphylococcal food poisoning outbreaks , 2008, Proteomics.
[38] Jeffrey R. Whiteaker,et al. Antibody-based enrichment of peptides on magnetic beads for mass-spectrometry-based quantification of serum biomarkers. , 2007, Analytical biochemistry.
[39] Douglas A Jeffery,et al. "Product ion monitoring" assay for prostate-specific antigen in serum using a linear ion-trap. , 2008, Journal of proteome research.
[40] M. Navarro,et al. Variations observed for insulin concentrations in an interlaboratory quality control program may be due to interferences between reagents and the matrix of the control materials. , 2007, Clinical biochemistry.
[41] Wilhelm Schänzer,et al. Insulins in equine urine: qualitative analysis by immunoaffinity purification and liquid chromatography/tandem mass spectrometry for doping control purposes in horse-racing. , 2008, Rapid communications in mass spectrometry : RCM.
[42] F. Vandenesch,et al. Isotope-labeled Protein Standards , 2007, Molecular & Cellular Proteomics.
[43] Shujia Dai,et al. Quantification of sifuvirtide in monkey plasma by an on-line solid-phase extraction procedure combined with liquid chromatography/electrospray ionization tandem mass spectrometry. , 2005, Rapid communications in mass spectrometry : RCM.
[44] D. Hochstrasser,et al. Relative quantification of proteins in human cerebrospinal fluids by MS/MS using 6-plex isobaric tags. , 2008, Analytical chemistry.
[45] Wilhelm Schänzer,et al. Qualitative determination of synthetic analogues of insulin in human plasma by immunoaffinity purification and liquid chromatography-tandem mass spectrometry for doping control purposes. , 2005, Analytical chemistry.
[46] M. Preece,et al. Pharmacokinetic studies of recombinant human insulin-like growth factor I (rhIGF-I)/rhIGF-binding protein-3 complex administered to patients with growth hormone insensitivity syndrome. , 2006, The Journal of clinical endocrinology and metabolism.
[47] E. Ezan,et al. Immunopurification and mass spectrometric quantification of the active form of a chimeric therapeutic antibody in human serum. , 2008, Analytical chemistry.
[48] Eric M Gage,et al. A strategy of plasma protein quantitation by selective reaction monitoring of an intact protein. , 2003, Analytical chemistry.
[49] R. Nelson,et al. Development of recombinant-based mass spectrometric immunoassay with application to resistin expression profiling. , 2006, Analytical chemistry.
[50] V. Mayya,et al. Proteomic applications of protein quantification by isotope-dilution mass spectrometry , 2006, Expert review of proteomics.
[51] E. Ezan,et al. Quantification of small therapeutic proteins in plasma by liquid chromatography-tandem mass spectrometry: application to an elastase inhibitor EPI-hNE4. , 2006, Analytical chemistry.
[52] Andrew N Hoofnagle,et al. Quantification of thyroglobulin, a low-abundance serum protein, by immunoaffinity peptide enrichment and tandem mass spectrometry. , 2008, Clinical chemistry.
[53] John C. Morris,et al. Comparison of thyrotropin-receptor antibodies measured by four commercially available methods with a bioassay that uses Fisher rat thyroid cells. , 2003, Clinical chemistry.
[54] M. Thevis,et al. Determination of Synacthen in human plasma using immunoaffinity purification and liquid chromatography/tandem mass spectrometry. , 2006, Rapid communications in mass spectrometry : RCM.
[55] M. Quaglia,et al. Amine-reactive isobaric tagging reagents: requirements for absolute quantification of proteins and peptides. , 2008, Analytical biochemistry.
[56] Jos H Beijnen,et al. Quantitative bioanalysis of peptides by liquid chromatography coupled to (tandem) mass spectrometry. , 2008, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
[57] R. Humerickhouse,et al. Investigation of the immunogenicity of a protein drug using equilibrium dialysis and liquid chromatography tandem mass spectrometry detection. , 2005, Analytical chemistry.
[58] Olivier Heudi,et al. Towards absolute quantification of therapeutic monoclonal antibody in serum by LC-MS/MS using isotope-labeled antibody standard and protein cleavage isotope dilution mass spectrometry. , 2008, Analytical chemistry.
[59] Hendrik Neubert,et al. Assessing immunogenicity in the presence of excess protein therapeutic using immunoprecipitation and quantitative mass spectrometry. , 2008, Analytical chemistry.
[60] M. Thevis,et al. Quantification of human insulin-like growth factor-1 and qualitative detection of its analogues in plasma using liquid chromatography/electrospray ionisation tandem mass spectrometry. , 2008, Rapid communications in mass spectrometry : RCM.
[61] Xinping Fang,et al. LC-MS/MS approach for quantification of therapeutic proteins in plasma using a protein internal standard and 2D-solid-phase extraction cleanup. , 2007, Analytical chemistry.
[62] T. Hoffmann,et al. Immunoprecipitation and liquid chromatographic-mass spectrometric determination of the peptide glucose-dependent insulinotropic polypeptides GIP1-42 and GIP3-42 from human plasma samples. New sensitive method to analyze physiological concentrations of peptide hormones. , 2001, Journal of chromatography. A.
[63] J. Hale,et al. Strategic use of immunoprecipitation and LC/MS/MS for trace-level protein quantification: myosin light chain 1, a biomarker of cardiac necrosis. , 2007, Analytical chemistry.
[64] G. Nicol,et al. Use of an Immunoaffinity-Mass Spectrometry-based Approach for the Quantification of Protein Biomarkers from Serum Samples of Lung Cancer Patients* , 2008, Molecular & Cellular Proteomics.
[65] Jeffrey R. Whiteaker,et al. Head-to-head comparison of serum fractionation techniques. , 2007, Journal of proteome research.
[66] N. Kitteringham,et al. Multiple reaction monitoring for quantitative biomarker analysis in proteomics and metabolomics. , 2009, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
[67] J. Koziol,et al. A critical evaluation of enzyme immunoassay kits for detection of antinuclear autoantibodies of defined specificities. III. Comparative performance characteristics of academic and manufacturers' laboratories. , 2003, The Journal of rheumatology.
[68] J. Lee,et al. Bioanalytical method development and validation for a large peptide HIV fusion inhibitor (Enfuvirtide, T-20) and its metabolite in human plasma using LC-MS/MS. , 2005, Journal of pharmaceutical and biomedical analysis.
[69] Leigh Anderson,et al. Quantitative Mass Spectrometric Multiple Reaction Monitoring Assays for Major Plasma Proteins* , 2006, Molecular & Cellular Proteomics.
[70] S. Gandy,et al. The profile of soluble amyloid beta protein in cultured cell media. Detection and quantification of amyloid beta protein and variants by immunoprecipitation-mass spectrometry. , 1996, The Journal of biological chemistry.
[71] S. Carr,et al. Quantitative, Multiplexed Assays for Low Abundance Proteins in Plasma by Targeted Mass Spectrometry and Stable Isotope Dilution*S , 2007, Molecular & Cellular Proteomics.
[72] E. Birks,et al. LC−MS/MS Method for Confirmation of Recombinant Human Erythropoietin and Darbepoetin α in Equine Plasma , 2007 .
[73] Stacy Lawrence. Biotech drug market steadily expands , 2005, Nature Biotechnology.
[74] E. Ezan,et al. Immuno-mass spectrometry assay of EPI-HNE4, a recombinant protein inhibitor of human elastase. , 2007, Rapid communications in mass spectrometry : RCM.
[75] D. Holtzman,et al. Quantitative analysis of amyloid beta peptides in cerebrospinal fluid of Alzheimer's disease patients by immunoaffinity purification and stable isotope dilution liquid chromatography/negative electrospray ionization tandem mass spectrometry. , 2006, Rapid communications in mass spectrometry : RCM.
[76] E. Birks,et al. Differentiation and identification of recombinant human erythropoietin and darbepoetin Alfa in equine plasma by LC-MS/MS for doping control. , 2008, Analytical chemistry.
[77] J. Banoub,et al. Absolute quantification of Atlantic salmon and rainbow trout vitellogenin by the 'signature peptide' approach using electrospray ionization QqToF tandem mass spectrometry. , 2006, Journal of mass spectrometry : JMS.
[78] Binodh DeSilva,et al. Recommendations for the Bioanalytical Method Validation of Ligand-Binding Assays to Support Pharmacokinetic Assessments of Macromolecules , 2003, Pharmaceutical Research.
[79] B. Davis,et al. LC-MS/MS Quantification of Zn-α2 Glycoprotein: A Potential Serum Biomarker for Prostate Cancer , 2007 .
[80] B. Meibohm,et al. Pharmacokinetic aspects of biotechnology products. , 2004, Journal of pharmaceutical sciences.
[81] R. Jansen,et al. Analysis of human serum by liquid chromatography-mass spectrometry: improved sample preparation and data analysis. , 2006, Journal of chromatography. A.
[82] P. Solter,et al. Quantification of NTproBNP in rat serum using immunoprecipitation and LC/MS/MS: a biomarker of drug-induced cardiac hypertrophy. , 2008, Analytical chemistry.
[83] R. Aebersold,et al. Selected reaction monitoring for quantitative proteomics: a tutorial , 2008, Molecular systems biology.
[84] W. Burkitt,et al. Toward Système International d'Unité-traceable protein quantification: from amino acids to proteins. , 2008, Analytical biochemistry.
[85] Gary Walsh,et al. Post-translational modifications in the context of therapeutic proteins , 2006, Nature Biotechnology.