The role of the prefrontal cortex in dynamic filtering

Functional neuroimaging and neuropsychological methods have broadened our understanding of the human prefrontal cortex. Converging evidence suggests that this brain region contributes to executive control of information processing. Both cognitive and neural-based models have attempted to delineate the manner in which the prefrontal cortex mediates executive control. An analysis of these findings and models suggests four prominent aspects of executive control—selecting, maintaining, updating, and rerouting information processing. These four aspects are couched in terms of dynamic filtering theory, which proposes that the prefrontal cortex acts as a selective gating or filtering mechanism that controls information processing.

[1]  A. Shimamura,et al.  Letter and category fluency in patients with frontal lobe lesions. , 1998, Neuropsychology.

[2]  Alan C. Evans,et al.  Dissociation of human mid-dorsolateral from posterior dorsolateral frontal cortex in memory processing. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[3]  D. Alan Allport,et al.  SHIFTING INTENTIONAL SET - EXPLORING THE DYNAMIC CONTROL OF TASKS , 1994 .

[4]  Alan C. Evans,et al.  Functional activation of the human frontal cortex during the performance of verbal working memory tasks. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[5]  Arthur P. Shimamura,et al.  Source memory impairment in patients with frontal lobe lesions , 1989, Neuropsychologia.

[6]  H S Levin,et al.  Frontal Lobe Dysfunction following Closed Head Injury. A Review of the Literature , 1990, The Journal of nervous and mental disease.

[7]  A. Luria Higher Cortical Functions in Man , 1980, Springer US.

[8]  Arthur P. Shimamura,et al.  Memory for the temporal order of events in patients with frontal lobe lesions and amnesic patients , 1990, Neuropsychologia.

[9]  J. Stroop Studies of interference in serial verbal reactions. , 1992 .

[10]  Frontal lobe dysfunction following closed head injury in children: Findings from neuropsychology and brain imaging. , 1997 .

[11]  J. B. Demb,et al.  Functional Magnetic Resonance Imaging of Semantic Memory Processes in the Frontal Lobes , 1996 .

[12]  D. Hebb MAN'S FRONTAL LOBES: A CRITICAL REVIEW , 1945 .

[13]  J. Desmond,et al.  Making memories: brain activity that predicts how well visual experience will be remembered. , 1998, Science.

[14]  M. Petrides,et al.  Specialized systems for the processing of mnemonic information within the primate frontal cortex. , 1996, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

[15]  P. Eslinger,et al.  Altered serial position learning after frontal lobe lesion , 1994, Neuropsychologia.

[16]  E. Perret The left frontal lobe of man and the suppression of habitual responses in verbal categorical behaviour. , 1974, Neuropsychologia.

[17]  Jordan Grafman,et al.  Handbook of Neuropsychology , 1991 .

[18]  T. Robbins,et al.  Planning and spatial working memory following frontal lobe lesions in man , 1990, Neuropsychologia.

[19]  J. Driver,et al.  Control of Cognitive Processes: Attention and Performance XVIII , 2000 .

[20]  J. Desmedt Attention, Voluntary Contraction and Event-Related Cerebral Potentials , 1977 .

[21]  A. Damasio On Some Functions of the Human Prefrontal Cortex a , 1995, Annals of the New York Academy of Sciences.

[22]  Bruce T. Volpe,et al.  Memory strategies with brain damage , 1988, Brain and Cognition.

[23]  Edward E. Smith,et al.  Temporal dynamics of brain activation during a working memory task , 1997, Nature.

[24]  Edward E. Smith,et al.  Spatial working memory in humans as revealed by PET , 1993, Nature.

[25]  R. Ivry,et al.  Response channel activation and the lateral prefrontal cortex , 1996, Neuropsychologia.

[26]  Keith J. Holyoak,et al.  Structure and Functions of the Human Prefrontal Cortex , 1996 .

[27]  P. Goldman-Rakic,et al.  Dorsolateral prefrontal lesions and oculomotor delayed-response performance: evidence for mnemonic "scotomas" , 1993, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[28]  S. Carlson,et al.  Distribution of cortical activation during visuospatial n-back tasks as revealed by functional magnetic resonance imaging. , 1998, Cerebral cortex.

[29]  G. J. Romanes,et al.  The Neocortex of Macaca mulatta , 1948 .

[30]  Jemett L. Desmond,et al.  Semantic encoding and retrieval in the left inferior prefrontal cortex: a functional MRI study of task difficulty and process specificity , 1995, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[31]  Leslie G. Ungerleider Two cortical visual systems , 1982 .

[32]  Arthur P. Shimamura,et al.  Spatial and color working memory in patients with lateral prefrontal cortex lesions , 2000, Psychobiology.

[33]  Brenda Milner,et al.  Design fluency: The invention of nonsense drawings after focal cortical lesions , 1977, Neuropsychologia.

[34]  Daniel L. Schacter,et al.  Retrieval without Recollection: An Experimental Analysis of Source Amnesia , 1984 .

[35]  M. Petrides Comparative architectonic analysis of the human and the macaque frontal cortex , 1994 .

[36]  Edward E. Smith,et al.  Dissociation of Storage and Rehearsal in Verbal Working Memory: Evidence From Positron Emission Tomography , 1996 .

[37]  D. Stuss,et al.  The Frontal Lobes , 1986 .

[38]  J. M. Warren,et al.  THE FRONTAL GRANULAR CORTEX AND BEHAVIOR , 1964 .

[39]  A P Shimamura,et al.  Cognitive impairment following frontal lobe damage and its relevance to human amnesia. , 1989, Behavioral neuroscience.

[40]  Robert T. Knight,et al.  Prefrontal cortex gating of auditory transmission in humans , 1989, Brain Research.

[41]  Morris Moscovitch,et al.  Cognitive resources and dual-task interference effects at retrieval in normal people: The role of the frontal lobes and medial temporal cortex. , 1994 .

[42]  V. Bruce Unsolved mysteries of the mind : tutorial essays in cognition , 1998 .

[43]  M. Farah,et al.  A unified account of cognitive impairments following frontal lobe damage: the role of working memory in complex, organized behavior. , 1993, Journal of experimental psychology. General.

[44]  S. Wise The Prefrontal Cortex: Executive and Cognitive Functions edited by A.C. Roberts, T.W. Robbins and L. Weiskrantz , 1999, Trends in Cognitive Sciences.

[45]  Gert Pfurtscheller,et al.  Progress in clinical neurophysiology. Vol. 1. Attention, voluntary contraction and event-related cerebral potentials: J.E. Desmedt (Ed.) (Karger, Basel, 256 p., 95 figs., 6 tab., 1977, DM 98.—) , 1979 .

[46]  Arthur P. Shimamura,et al.  Memory and frontal lobe function. , 1995 .

[47]  James E. Skinner,et al.  Central Gating Mechanisms That Regulate Event-Related Potentials and Behavior , 1984 .

[48]  R. Knight,et al.  Prefrontal cortex regulates inhibition and excitation in distributed neural networks. , 1999, Acta psychologica.

[49]  Y. Miyashita,et al.  Common inhibitory mechanism in human inferior prefrontal cortex revealed by event-related functional MRI. , 1999, Brain : a journal of neurology.

[50]  S. Grossberg The Link between Brain Learning, Attention, and Consciousness , 1999, Consciousness and Cognition.

[51]  Dean C. Delis,et al.  Componential analysis of problem-solving ability: Performance of patients with frontal lobe damage and amnesic patients on a new sorting test , 1992, Neuropsychologia.

[52]  M. Macmillan A wonderful journey through skull and brains: The travels of Mr. Gage's tamping iron , 1986, Brain and Cognition.

[53]  Earl K. Miller,et al.  Selective representation of relevant information by neurons in the primate prefrontal cortex , 1998, Nature.

[54]  B. Milner,et al.  Interhemispheric differences in the localization of psychological processes in man. , 1971, British medical bulletin.

[55]  R. Desimone,et al.  Neural Mechanisms of Visual Working Memory in Prefrontal Cortex of the Macaque , 1996, The Journal of Neuroscience.

[56]  J. Fuster Prefrontal Cortex , 2018 .

[57]  Karl J. Friston,et al.  A PET study of word finding , 1991, Neuropsychologia.

[58]  T. Robbins,et al.  The prefrontal cortex: Executive and cognitive functions. , 1998 .

[59]  R. Desimone,et al.  Neural mechanisms of selective visual attention. , 1995, Annual review of neuroscience.

[60]  J. Jonides,et al.  Storage and executive processes in the frontal lobes. , 1999, Science.

[61]  B. Milner,et al.  Deficits on subject-ordered tasks after frontal- and temporal-lobe lesions in man , 1982, Neuropsychologia.

[62]  M. D’Esposito,et al.  The neural basis of the central executive system of working memory , 1995, Nature.

[63]  T. Shallice Specific impairments of planning. , 1982, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

[64]  B L Miller,et al.  Dietary changes, compulsions and sexual behavior in frontotemporal degeneration. , 1995, Dementia.

[65]  T. Robbins,et al.  Dissociation in prefrontal cortex of affective and attentional shifts , 1996, Nature.

[66]  Alan C. Evans,et al.  Functional activation of the human ventrolateral frontal cortex during mnemonic retrieval of verbal information. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[67]  R. Knight,et al.  Prefrontal and posterior cortical activation during auditory working memory. , 1996, Brain research. Cognitive brain research.

[68]  Marcia K. Johnson,et al.  Source monitoring. , 1993, Psychological bulletin.

[69]  Karl J. Friston,et al.  Investigations of the functional anatomy of attention using the stroop test , 1993, Neuropsychologia.

[70]  B. Milner,et al.  Frontal lobes and the temporal organization of memory. , 1985, Human neurobiology.

[71]  Edward Awh,et al.  Spatial versus Object Working Memory: PET Investigations , 1995, Journal of Cognitive Neuroscience.

[72]  R. Knight,et al.  Gating of somatosensory input by human prefrontal cortex , 1990, Brain Research.

[73]  R. Dolan,et al.  Dissociating prefrontal and hippocampal function in episodic memory encoding , 1997, Nature.

[74]  J. Jonides,et al.  Inhibition in verbal working memory revealed by brain activation. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[75]  J. Duncan,et al.  Intelligence and the Frontal Lobe: The Organization of Goal-Directed Behavior , 1996, Cognitive Psychology.

[76]  P. Goldman-Rakic The prefrontal landscape: implications of functional architecture for understanding human mentation and the central executive. , 1996, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

[77]  A Ptito,et al.  Visual‐spatial localization by patients with frontallobe lesions invading or sparing area 46 , 1995, Neuroreport.

[78]  Stephen Grossberg,et al.  Studies of mind and brain , 1982 .

[79]  A. Walker,et al.  A cytoarchitectural study of the prefrontal area of the macaque monkey , 1940 .

[80]  R. Buckner Beyond HERA: Contributions of specific prefrontal brain areas to long-term memory retrieval , 1996, Psychonomic bulletin & review.

[81]  F. Craik,et al.  Hemispheric encoding/retrieval asymmetry in episodic memory: positron emission tomography findings. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[82]  Bradley R Postle,et al.  The dependence of span and delayed-response performance on prefrontal cortex , 1999, Neuropsychologia.

[83]  Edward E. Smith,et al.  Verbal Working Memory Load Affects Regional Brain Activation as Measured by PET , 1997, Journal of Cognitive Neuroscience.

[84]  Malcolm Macmillan,et al.  An odd kind of fame : stories of Phineas Gage , 2000 .

[85]  J. Harlow Passage of an Iron Rod Through the Head , 1999 .

[86]  A. Dale,et al.  Building memories: remembering and forgetting of verbal experiences as predicted by brain activity. , 1998, Science.

[87]  F. Lhermitte,et al.  Human autonomy and the frontal lobes. Part II: Patient behavior in complex and social situations: The “environmental dependency syndrome” , 1986, Annals of neurology.

[88]  D. Pandya,et al.  Comparison of prefrontal architecture and connections. , 1996, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

[89]  Robert T. Knight,et al.  Susceptibility to Memory Interference Effects following Frontal Lobe Damage: Findings from Tests of Paired-Associate Learning , 1995, Journal of Cognitive Neuroscience.

[90]  M. Moscovitch,et al.  Attention and Performance 15: Conscious and Nonconscious Information Processing , 1994 .

[91]  P. Goldman-Rakic,et al.  Dissociation of object and spatial processing domains in primate prefrontal cortex. , 1993, Science.

[92]  Jonathan D. Cohen,et al.  Conflict monitoring versus selection-for-action in anterior cingulate cortex , 1999, Nature.

[93]  W. C. Halstead Brain and intelligence : a quantitative study of the frontal Lobes , 1948 .

[94]  V. Mountcastle,et al.  Higher functions of the brain , 1987 .

[95]  E. Bizzi,et al.  The Cognitive Neurosciences , 1996 .

[96]  Colin M. Macleod Half a century of research on the Stroop effect: an integrative review. , 1991, Psychological bulletin.

[97]  M. D’Esposito,et al.  Functional MRI studies of spatial and nonspatial working memory. , 1998, Brain research. Cognitive brain research.

[98]  K. Dunbar,et al.  Toward a Cognitive Account of Frontal Lobe Function: Simulating Frontal Lobe Deficits in Normal Subjects a , 1995, Annals of the New York Academy of Sciences.

[99]  J. Cohen,et al.  Context, cortex, and dopamine: a connectionist approach to behavior and biology in schizophrenia. , 1992, Psychological review.

[100]  K. Goldstein The Significance of the Frontal Lobes for Mental Performances* , 1936, The Journal of neurology and psychopathology.

[101]  E. Tulving,et al.  PET studies of encoding and retrieval: The HERA model , 1996, Psychonomic bulletin & review.

[102]  Irene P. Kan,et al.  Verb generation in patients with focal frontal lesions: a neuropsychological test of neuroimaging findings. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[103]  T. Robbins,et al.  Contrasting mechanisms of impaired attentional set-shifting in patients with frontal lobe damage or Parkinson's disease. , 1993, Brain : a journal of neurology.

[104]  A. Anderson,et al.  An fMRI study of stroop word-color interference: evidence for cingulate subregions subserving multiple distributed attentional systems , 1999, Biological Psychiatry.

[105]  S. Grossberg Studies of mind and brain : neural principles of learning, perception, development, cognition, and motor control , 1982 .

[106]  Marcia K. Johnson,et al.  Left prefrontal activation during episodic remembering: an event‐related fMRI study , 1998, Neuroreport.

[107]  M. Mishkin,et al.  Non-spatial memory after selective prefrontal lesions in monkeys , 1978, Brain Research.

[108]  G. McCarthy,et al.  Echo-planar magnetic resonance imaging studies of frontal cortex activation during word generation in humans. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[109]  C. Jacobsen,et al.  Studies of cerebral function in primates. I. The functions of the frontal association areas in monkeys. , 1936 .

[110]  S C Rao,et al.  Integration of what and where in the primate prefrontal cortex. , 1997, Science.