Reductions in microfilaridermia by repeated ivermectin treatment are associated with lower Plasmodium-specific Th17 immune responses in Onchocerca volvulus-infected individuals

[1]  A. Hoerauf,et al.  Hyperreactive Onchocerciasis is Characterized by a Combination of Th17-Th2 Immune Responses and Reduced Regulatory T Cells , 2015, PLoS neglected tropical diseases.

[2]  A. Hoerauf,et al.  Immunoepidemiological Profiling of Onchocerciasis Patients Reveals Associations with Microfilaria Loads and Ivermectin Intake on Both Individual and Community Levels , 2014, PLoS neglected tropical diseases.

[3]  T. Ndung’u,et al.  Neutrophil counts in persons of African origin , 2014, Current opinion in hematology.

[4]  A. Hoerauf,et al.  54 – The Filariases , 2014 .

[5]  A. Yoshimura,et al.  IL‐23 protection against Plasmodium berghei infection in mice is partially dependent on IL‐17 from macrophages , 2013, European journal of immunology.

[6]  T. Nutman,et al.  Regulatory T Cell Subsets in Filarial Infection and Their Function , 2013, Front. Immunol..

[7]  G. Young,et al.  Counterpoise between the microbiome, host immune activation and pathology. , 2013, Current opinion in immunology.

[8]  African Programme for Onchocerciasis Control: meeting of National Onchocerciasis Task Forces, September 2013. , 2013, Releve epidemiologique hebdomadaire.

[9]  M. Fay,et al.  Filariasis Attenuates Anemia and Proinflammatory Responses Associated with Clinical Malaria: A Matched Prospective Study in Children and Young Adults , 2012, PLoS neglected tropical diseases.

[10]  C. Deming,et al.  Compartmentalized Control of Skin Immunity by Resident Commensals , 2012, Science.

[11]  M. Lacerda,et al.  Interleukin-17 producing T helper cells are increased during natural Plasmodium vivax infection. , 2012, Acta tropica.

[12]  P. Soboslay,et al.  Chemokines and cytokines in patients with an occult Onchocerca volvulus infection. , 2012, Microbes and infection.

[13]  A. Meryk,et al.  Cutting Edge: Inhibition of IL-6 Trans-Signaling Protects from Malaria-Induced Lethality in Mice , 2012, The Journal of Immunology.

[14]  A. Hoerauf,et al.  Elevated Adaptive Immune Responses Are Associated with Latent Infections of Wuchereria bancrofti , 2012, PLoS neglected tropical diseases.

[15]  S. Larsen,et al.  Polymorphisms in the RNASE3 Gene Are Associated with Susceptibility to Cerebral Malaria in Ghanaian Children , 2011, PloS one.

[16]  B. Mayala,et al.  Plasmodium falciparum and helminth coinfections among schoolchildren in relation to agro-ecosystems in Mvomero District, Tanzania. , 2011, Acta tropica.

[17]  A. Hoerauf,et al.  Onchocerciasis: the Role of Wolbachia Bacterial Endosymbionts in Parasite Biology, Disease Pathogenesis, and Treatment , 2011, Clinical Microbiology Reviews.

[18]  A. Hoerauf,et al.  Filariasis in Africa--treatment challenges and prospects. , 2011, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

[19]  T. Nutman,et al.  Filarial Infection Suppresses Malaria-Specific Multifunctional Th1 and Th17 Responses in Malaria and Filarial Coinfections , 2011, The Journal of Immunology.

[20]  L. Rénia,et al.  Inhibitory Effect of TNF-α on Malaria Pre-Erythrocytic Stage Development: Influence of Host Hepatocyte/Parasite Combinations , 2011, PloS one.

[21]  Achim Hoerauf,et al.  Lymphatic filariasis and onchocerciasis , 2010, The Lancet.

[22]  A. Hoerauf,et al.  Induction of immunoglobulin G4 in human filariasis: an indicator of immunoregulation , 2010, Annals of tropical medicine and parasitology.

[23]  A. Hoerauf,et al.  Low levels of transforming growth factor-beta (TGF-beta) and reduced suppression of Th2-mediated inflammation in hyperreactive human onchocerciasis , 2010, Parasitology.

[24]  T. Nutman,et al.  At Homeostasis Filarial Infections Have Expanded Adaptive T Regulatory but Not Classical Th2 Cells , 2010, The Journal of Immunology.

[25]  A. Basu,et al.  Japanese Encephalitis—A Pathological and Clinical Perspective , 2009, PLoS neglected tropical diseases.

[26]  T. Nutman,et al.  Patent Filarial Infection Modulates Malaria-Specific Type 1 Cytokine Responses in an IL-10-Dependent Manner in a Filaria/Malaria-Coinfected Population12 , 2009, The Journal of Immunology.

[27]  L. Konaté,et al.  Feasibility of Onchocerciasis Elimination with Ivermectin Treatment in Endemic Foci in Africa: First Evidence from Studies in Mali and Senegal , 2009, PLoS neglected tropical diseases.

[28]  Angelo B. Lipira,et al.  Filarial Lymphedema Is Characterized by Antigen-Specific Th1 and Th17 Proinflammatory Responses and a Lack of Regulatory T Cells , 2009, PLoS neglected tropical diseases.

[29]  A. Hoerauf Filariasis: new drugs and new opportunities for lymphatic filariasis and onchocerciasis , 2008, Current opinion in infectious diseases.

[30]  M. Muwanga,et al.  Plasmodium falciparum and helminth coinfection in a semi urban population of pregnant women in Uganda. , 2008, The Journal of infectious diseases.

[31]  A. Hoerauf,et al.  Natural death of adult Onchocerca volvulus and filaricidal effects of doxycycline induce local FOXP3+/CD4+ regulatory T cells and granzyme expression. , 2008, Microbes and infection.

[32]  D. Akinboye,et al.  Onchocerciasis and plasmodiasis: concurrent infectionin Garaha-Dutse community, Adamawa State Nigeria , 2008 .

[33]  I. Clark,et al.  Understanding the role of inflammatory cytokines in malaria and related diseases. , 2008, Travel medicine and infectious disease.

[34]  T. Nutman,et al.  CD4(+) (and not CD25+) T cells are the predominant interleukin-10-producing cells in the circulation of filaria-infected patients. , 2008, The Journal of infectious diseases.

[35]  R. Fimmers,et al.  Wolbachia endobacteria depletion by doxycycline as antifilarial therapy has macrofilaricidal activity in onchocerciasis: a randomized placebo-controlled study , 2007, Medical Microbiology and Immunology.

[36]  P. Cazenave,et al.  Clusters of cytokines determine malaria severity in Plasmodium falciparum-infected patients from endemic areas of Central India. , 2006, The Journal of infectious diseases.

[37]  C. Mbogo,et al.  Concomitant infections of Plasmodium falciparum and Wuchereria bancrofti on the Kenyan coast , 2006, Filaria journal.

[38]  T. Nutman,et al.  Regulatory Networks Induced by Live Parasites Impair Both Th1 and Th2 Pathways in Patent Lymphatic Filariasis: Implications for Parasite Persistence1 , 2006, The Journal of Immunology.

[39]  M. Saeftel,et al.  Immunomodulation by filarial nematodes , 2005, Parasite immunology.

[40]  H. Ball,et al.  Early Cytokine Production Is Associated with Protection from Murine Cerebral Malaria , 2005, Infection and Immunity.

[41]  A. Hoerauf,et al.  T Regulatory-1 Cells Induce IgG4 Production by B Cells: Role of IL-101 , 2005, The Journal of Immunology.

[42]  T. Kruppa,et al.  Efficiency of Simulium sanctipauli as a vector of Onchocerca volvulus in the forest zone of Ghana , 2004, Medical and veterinary entomology.

[43]  N. Brattig Pathogenesis and host responses in human onchocerciasis: impact of Onchocerca filariae and Wolbachia endobacteria. , 2004, Microbes and infection.

[44]  H. Bujard,et al.  The Merozoite Surface Protein 1 Complex of Human Malaria Parasite Plasmodium falciparum , 2003, Journal of Biological Chemistry.

[45]  D. Chadee,et al.  Short communication: Concomitant malaria and filariasis infections in Georgetown, Guyana , 2003, Tropical medicine & international health : TM & IH.

[46]  A. Hoerauf,et al.  Antigen-specific cellular hyporesponsiveness in a chronic human helminth infection is mediated by Th3/Tr1-type cytokines IL-10 and transforming growth factor-β but not by a Th1 to Th2 shift , 2000 .

[47]  A. Hoerauf,et al.  Endosymbiotic bacteria in worms as targets for a novel chemotherapy in filariasis , 2000, The Lancet.

[48]  Lin Chen,et al.  Neutrophils play a critical role in the pathogenesis of experimental cerebral malaria , 2000, Clinical and experimental immunology.

[49]  A. Hoerauf,et al.  Antigen-specific cellular hyporesponsiveness in a chronic human helminth infection is mediated by T(h)3/T(r)1-type cytokines IL-10 and transforming growth factor-beta but not by a T(h)1 to T(h)2 shift. , 2000, International immunology.

[50]  P. Kremsner,et al.  Increased frequency of Th2-type cytokine-producing T cells in microfilaremic loiasis. , 1999, The American journal of tropical medicine and hygiene.

[51]  Nkrumah,et al.  Increased eosinophil activity in acute Plasmodium falciparum infection—association with cerebral malaria , 1998, Clinical and experimental immunology.

[52]  R. Speare,et al.  A comparison of the Og4C3 antigen capture ELISA, the Knott test, an IgG4 assay and clinical signs, in the diagnosis of Bancroftian filariasis. , 1993, Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit.