Scatter correction for full-fan volumetric CT using a stationary beam blocker in a single full scan.

PURPOSE Applications of volumetric CT (VCT) are hampered by shading and streaking artifacts in the reconstructed images. These artifacts are mainly due to strong x-ray scatter signals accompanied with the large illumination area within one projection, which lead to CT number inaccuracy, image contrast loss and spatial nonuniformity. Although different scatter correction algorithms have been proposed in literature, a standard solution still remains unclear. Measurement-based methods use a beam blocker to acquire scatter samples. These techniques have unrivaled advantages over other existing algorithms in that they are simple and efficient, and achieve high scatter estimation accuracy without prior knowledge of the imaged object. Nevertheless, primary signal loss is inevitable in the scatter measurement, and multiple scans or moving the beam blocker during data acquisition are typically employed to compensate for the missing primary data. In this paper, we propose a new measurement-based scatter correction algorithm without primary compensation for full-fan VCT. An accurate reconstruction is obtained with one single-scan and a stationary x-ray beam blocker, two seemingly incompatible features which enable simple and efficient scatter correction without increase of scan time or patient dose. METHODS Based on the CT reconstruction theory, we distribute the blocked data over the projection area where primary signals are considered approximately redundant in a full scan, such that the CT image quality is not degraded even with primary loss. Scatter is then accurately estimated by interpolation and scatter-corrected CT images are obtained using an FDK-based reconstruction algorithm. RESULTS The proposed method is evaluated using two phantom studies on a tabletop CBCT system. On the Catphan©600 phantom, our approach reduces the reconstruction error from 207 Hounsfield unit (HU) to 9 HU in the selected region of interest, and improves the image contrast by a factor of 2.0 in the high-contrast regions. On an anthropomorphic head phantom, the reconstruction error is reduced from 97 HU to 6 HU in the soft tissue region and image spatial nonuniformity decreases from 27% to 5% after correction. CONCLUSIONS Our method inherits the main advantages of measurement-based methods while avoiding their shortcomings. It has the potential to become a practical scatter correction solution widely implementable on different VCT systems.

[1]  P. C. Johns,et al.  Scattered radiation in diagnostic radiology: magnitudes, effects and methods of reduction , 1983 .

[2]  L. Feldkamp,et al.  Practical cone-beam algorithm , 1984 .

[3]  J. Boone,et al.  An analytical model of the scattered radiation distribution in diagnostic radiology. , 1988, Medical physics.

[4]  A. Macovski,et al.  Dual-energy x-ray projection imaging: two sampling schemes for the correction of scattered radiation. , 1988, Medical physics.

[5]  D. Jaffray,et al.  Optimization of x-ray imaging geometry (with specific application to flat-panel cone-beam computed tomography). , 2000, Medical physics.

[6]  K. Bae,et al.  Efficient correction for CT image artifacts caused by objects extending outside the scan field of view. , 2000, Medical physics.

[7]  M. Endo,et al.  Effect of scattered radiation on image noise in cone beam CT. , 2001, Medical physics.

[8]  Ruola Ning,et al.  X-ray scatter correction algorithm for cone beam CT imaging. , 2004, Medical physics.

[9]  Zhengrong Liang,et al.  Noise reduction for low-dose single-slice Helical CT sinogram , 2004 .

[10]  Freek J. Beekman,et al.  Accelerated simulation of cone beam X-ray scatter projections , 2004, IEEE Transactions on Medical Imaging.

[11]  Z. Liang,et al.  Noise reduction for low-dose single-slice Helical CT sinogram , 2006, IEEE Symposium Conference Record Nuclear Science 2004..

[12]  D. Jaffray,et al.  The influence of antiscatter grids on soft-tissue detectability in cone-beam computed tomography with flat-panel detectors. , 2004, Medical physics.

[13]  J. Boone,et al.  Evaluation of x-ray scatter properties in a dedicated cone-beam breast CT scanner. , 2005, Medical physics.

[14]  D. Hristov,et al.  Cone beam X-ray scatter removal via image frequency modulation and filtering , 2005, 2005 IEEE Engineering in Medicine and Biology 27th Annual Conference.

[15]  J. Boone,et al.  Evaluation of x-ray scatter properties in a dedicated cone-beam breast CT scanner. , 2005, Medical physics.

[16]  D. Hristov,et al.  TU‐D‐I‐611‐08: Cone Beam X‐Ray Scatter Removal Via Image Frequency Modulation and Filtering , 2005 .

[17]  Lei Zhu,et al.  X-ray scatter correction for cone-beam CT using moving blocker array , 2005, SPIE Medical Imaging.

[18]  P. J. Arsenault,et al.  Image reconstruction from the Compton scattering of X-ray fan beams in thick/dense objects , 2006, IEEE Transactions on Nuclear Science.

[19]  R. Fahrig,et al.  TH‐E‐330A‐04: Investigation Into the Cause of a New Artifact in Cone Beam CT Reconstructions On a Flat Panel Imager , 2006 .

[20]  S. Richard,et al.  A simple, direct method for x-ray scatter estimation and correction in digital radiography and cone-beam CT. , 2005, Medical physics.

[21]  G. Virshup,et al.  TH‐E‐330A‐06: Scatter Characterization in Cone‐Beam CT Systems with Offset Flat Panel Imagers , 2006 .

[22]  W. Kalender,et al.  Combining deterministic and Monte Carlo calculations for fast estimation of scatter intensities in CT , 2006, Physics in medicine and biology.

[23]  J. Hsieh,et al.  A three-dimensional-weighted cone beam filtered backprojection (CB-FBP) algorithm for image reconstruction in volumetric CT—helical scanning , 2006, Physics in medicine and biology.

[24]  Jing Wang,et al.  Penalized weighted least-squares approach to sinogram noise reduction and image reconstruction for low-dose X-ray computed tomography , 2006, IEEE Transactions on Medical Imaging.

[25]  Z. Liang,et al.  Noise reduction for low-dose single-slice Helical CT sinogram , 2006, IEEE Symposium Conference Record Nuclear Science 2004..

[26]  S. Mori,et al.  Magnitude and effects of x-ray scatter in a 256-slice CT scanner. , 2006, Medical physics.

[27]  Lei Zhu,et al.  Scatter Correction Method for X-Ray CT Using Primary Modulation: Theory and Preliminary Results , 2006, IEEE Transactions on Medical Imaging.

[28]  Günter Lauritsch,et al.  Truncation correction for oblique filtering lines. , 2008, Medical physics.

[29]  T. Marchant,et al.  Shading correction algorithm for improvement of cone-beam CT images in radiotherapy , 2008, Physics in medicine and biology.

[30]  D. Jaffray,et al.  The influence of bowtie filtration on cone-beam CT image quality , 2008 .

[31]  J. Pouliot,et al.  Focused beam-stop array for the measurement of scatter in megavoltage portal and cone beam CT imaging. , 2008, Medical physics.

[32]  Bruno De Man,et al.  An outlook on x-ray CT research and development. , 2008, Medical physics.

[33]  Lei Zhu,et al.  Noise suppression in scatter correction for cone-beam CT. , 2009, Medical physics.

[34]  Josh Star-Lack,et al.  Efficient scatter correction using asymmetric kernels , 2009, Medical Imaging.

[35]  D. Jaffray,et al.  Implementation and characterization of a 320-slice volumetric CT scanner for simulation in radiation oncology. , 2009, Medical physics.

[36]  D. Jaffray,et al.  The influence of bowtie filtration on cone-beam CT image quality. , 2007, Medical physics.

[37]  Lei Zhu,et al.  Scatter correction for cone-beam CT in radiation therapy. , 2009 .

[38]  Lei Zhu,et al.  Noise reduction in low-dose x-ray fluoroscopy for image-guided radiation therapy. , 2009, International journal of radiation oncology, biology, physics.

[39]  Lei Zhu,et al.  Shading correction for on-board cone-beam CT in radiation therapy using planning MDCT images. , 2010, Medical physics.

[40]  T. Zhu Overview of X-ray Scatter in Cone-beam Computed Tomography and Its Correction Methods , 2010 .

[41]  Timothy D. Solberg,et al.  Scatter correction for cone-beam computed tomography using moving blocker strips: a preliminary study. , 2010 .

[42]  Ning Wen,et al.  Combining scatter reduction and correction to improve image quality in cone-beam computed tomography (CBCT). , 2010, Medical physics.

[43]  N. R. Bennett,et al.  Scatter correction method for x-ray CT using primary modulation: phantom studies. , 2010, Medical physics.

[44]  P. Lambin,et al.  Dose recalculation in megavoltage cone-beam CT for treatment evaluation: removal of cupping and truncation artefacts in scans of the thorax and abdomen. , 2010, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[45]  Lei Zhu,et al.  Modulator design for x-ray scatter correction using primary modulation: material selection. , 2010, Medical physics.

[46]  Lei Zhu,et al.  A Patient Set-up Protocol Based on Partially Blocked Cone-beam CT , 2010, Technology in cancer research & treatment.

[47]  F. Rybicki,et al.  CT Coronary Angiography: 256-Slice and 320-Detector Row Scanners , 2010, Current cardiology reports.

[48]  J. Boone,et al.  Experimental validation of a method characterizing bow tie filters in CT scanners using a real-time dose probe. , 2011, Medical physics.