Macrophage-derived IL-1β stimulates Wnt signaling and growth of colon cancer cells; a crosstalk interrupted by vitamin D3

[1]  G. Bhagat,et al.  Overexpression of interleukin-1beta induces gastric inflammation and cancer and mobilizes myeloid-derived suppressor cells in mice. , 2008, Cancer cell.

[2]  A. Muñoz,et al.  Vitamin D and Wnt/beta-catenin pathway in colon cancer: role and regulation of DICKKOPF genes. , 2008, Anticancer research.

[3]  K. Hotzel,et al.  Inhibition of fibroblast growth factor 19 reduces tumor growth by modulating beta-catenin signaling. , 2008, Cancer research.

[4]  T. Lawrence,et al.  “Re-educating” tumor-associated macrophages by targeting NF-κB , 2008, The Journal of experimental medicine.

[5]  H. Saya,et al.  Activated macrophages promote Wnt signalling through tumour necrosis factor-α in gastric tumour cells , 2008, The EMBO journal.

[6]  Kylie L. Gorringe,et al.  No evidence of clonal somatic genetic alterations in cancer-associated fibroblasts from human breast and ovarian carcinomas , 2008, Nature Genetics.

[7]  P. Allavena,et al.  The inflammatory micro-environment in tumor progression: the role of tumor-associated macrophages. , 2008, Critical reviews in oncology/hematology.

[8]  H. Tomita,et al.  Further upregulation of beta-catenin/Tcf transcription is involved in the development of macroscopic tumors in the colon of ApcMin/+ mice. , 2008, Carcinogenesis.

[9]  R. Weissleder,et al.  Mast cells are an essential hematopoietic component for polyp development , 2007, Proceedings of the National Academy of Sciences.

[10]  M. Bissonnette,et al.  A vitamin D analogue inhibits colonic carcinogenesis in the AOM/DSS model. , 2007, The Journal of surgical research.

[11]  L. Augenlicht,et al.  Histone deacetylase inhibitors induce cell death selectively in cells that harbor activated kRasV12: The role of signal transducers and activators of transcription 1 and p21. , 2007, Cancer research.

[12]  Wan-Wan Lin,et al.  A cytokine-mediated link between innate immunity, inflammation, and cancer. , 2007, The Journal of clinical investigation.

[13]  R. Palmqvist,et al.  High Macrophage Infiltration along the Tumor Front Correlates with Improved Survival in Colon Cancer , 2007, Clinical Cancer Research.

[14]  P. Comoglio,et al.  A positive feedback loop between hepatocyte growth factor receptor and β-catenin sustains colorectal cancer cell invasive growth , 2007, Oncogene.

[15]  M. Sporn,et al.  The tumour microenvironment as a target for chemoprevention , 2007, Nature Reviews Cancer.

[16]  Zhi-Ren Liu,et al.  P68 RNA Helicase Mediates PDGF-Induced Epithelial Mesenchymal Transition by Displacing Axin from β-Catenin , 2006, Cell.

[17]  M. Lipkin,et al.  Mechanisms of action of vitamin D: recent findings and new questions. , 2006, Journal of medicinal food.

[18]  Xin-Yuan Fu,et al.  Smad4 signalling in T cells is required for suppression of gastrointestinal cancer , 2006, Nature.

[19]  R. Sinha,et al.  Inflammation-Related Gene Polymorphisms and Colorectal Adenoma , 2006, Cancer Epidemiology Biomarkers & Prevention.

[20]  J. Welsh,et al.  The Molecular Basis of Vitamin D Receptor and β-Catenin Crossregulation , 2006 .

[21]  J. Sakong,et al.  Janus Kinase-Signal Transducer and Activator of Transcription Mediates Phosphatidic Acid-Induced Interleukin (IL)-1β and IL-6 Production , 2006, Molecular Pharmacology.

[22]  A. Sica,et al.  A distinct and unique transcriptional program expressed by tumor-associated macrophages (defective NF-kappaB and enhanced IRF-3/STAT1 activation). , 2006, Blood.

[23]  G. Meijer,et al.  Macrophages direct tumour histology and clinical outcome in a colon cancer model , 2005, The Journal of pathology.

[24]  L. Augenlicht,et al.  Oncogenic Ras increases sensitivity of colon cancer cells to 5-FU-induced apoptosis , 2005, Oncogene.

[25]  D. Gabrilovich,et al.  STAT1 Signaling Regulates Tumor-Associated Macrophage-Mediated T Cell Deletion1 , 2005, The Journal of Immunology.

[26]  Michael Karin,et al.  Nod2 Mutation in Crohn's Disease Potentiates NF-κB Activity and IL-1ß Processing , 2005, Science.

[27]  Jason M Doherty,et al.  Activated macrophages are an adaptive element of the colonic epithelial progenitor niche necessary for regenerative responses to injury. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[28]  L. Augenlicht,et al.  Oncogenic Ras Promotes Butyrate-induced Apoptosis through Inhibition of Gelsolin Expression* , 2004, Journal of Biological Chemistry.

[29]  A. Bernad,et al.  The transcription factor SNAIL represses vitamin D receptor expression and responsiveness in human colon cancer , 2004, Nature Medicine.

[30]  M. Taketo Shutting down Wnt signal–activated cancer , 2004, Nature Genetics.

[31]  Wei Dong Chen,et al.  Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer , 2004, Nature Genetics.

[32]  Johan Moan,et al.  Vitamin D3 from sunlight may improve the prognosis of breast-, colon- and prostate cancer (Norway) , 2004, Cancer Causes & Control.

[33]  S. Byers,et al.  Trans-repression of β-Catenin Activity by Nuclear Receptors* , 2003, Journal of Biological Chemistry.

[34]  L. Augenlicht,et al.  Inhibition of interferon γ signaling by the short chain fatty acid butyrate , 2003 .

[35]  M. Lipkin,et al.  Chemoprevention of colon cancer by calcium, vitamin D and folate: molecular mechanisms , 2003, Nature Reviews Cancer.

[36]  J. Said,et al.  Vitamin D2 analog 19-nor-1,25-dihydroxyvitamin D2: antitumor activity against leukemia, myeloma, and colon cancer cells. , 2003, Journal of the National Cancer Institute.

[37]  N. Perrimon,et al.  The Promise and Perils of Wnt Signaling Through β-Catenin , 2002, Science.

[38]  R. Knuechel,et al.  Variable β-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[39]  A. G. de Herreros,et al.  Vitamin D3 promotes the differentiation of colon carcinoma cells by the induction of E-cadherin and the inhibition of β-catenin signaling , 2001, The Journal of cell biology.

[40]  S. Kitano,et al.  Angiogenin expression in human colorectal cancer: the role of focal macrophage infiltration. , 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.

[41]  J. Potter,et al.  Calcium, vitamin D, sunshine exposure, dairy products and colon cancer risk (United States) , 2000, Cancer Causes & Control.

[42]  A. C. Webb,et al.  A novel STAT-like factor mediates lipopolysaccharide, interleukin 1 (IL-1), and IL-6 signaling and recognizes a gamma interferon activation site-like element in the IL1B gene , 1996, Molecular and cellular biology.

[43]  P. Cohen,et al.  Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B , 1995, Nature.

[44]  S. Shirasawa,et al.  Altered growth of human colon cancer cell lines disrupted at activated Ki-ras. , 1993, Science.

[45]  C. Boone,et al.  Calcium, vitamin D, and colon cancer. , 1992, Cancer research.

[46]  K. Siziopikou,et al.  Impaired tumoricidal function of alveolar macrophages from patients with non‐small cell lung cancer , 1991, Cancer.

[47]  C. Garland,et al.  SERUM 25-HYDROXYVITAMIN D AND COLON CANCER: EIGHT-YEAR PROSPECTIVE STUDY , 1989, The Lancet.

[48]  K. Tada,et al.  Induction of maturation in cultured human monocytic leukemia cells by a phorbol diester. , 1982, Cancer research.

[49]  J. Welsh,et al.  The molecular basis of vitamin D receptor and beta-catenin crossregulation. , 2006, Molecular cell.

[50]  Mina J Bissell,et al.  Context, tissue plasticity, and cancer: are tumor stem cells also regulated by the microenvironment? , 2005, Cancer cell.

[51]  J. Pollard Tumour-educated macrophages promote tumour progression and metastasis , 2004, Nature Reviews Cancer.

[52]  L. Augenlicht,et al.  Inhibition of interferon gamma signaling by the short chain fatty acid butyrate. , 2003, Molecular cancer research : MCR.

[53]  S. Byers,et al.  Trans-repression of beta-catenin activity by nuclear receptors. , 2003, The Journal of biological chemistry.

[54]  N. Perrimon,et al.  The promise and perils of Wnt signaling through beta-catenin. , 2002, Science.

[55]  W. Hohenberger,et al.  Nuclear overexpression of the oncoprotein beta-catenin in colorectal cancer is localized predominantly at the invasion front. , 1998, Pathology, research and practice.