Strategies for analysis of glycoprotein glycosylation.

[1]  André M Deelder,et al.  Glycoproteomics based on tandem mass spectrometry of glycopeptides. , 2007, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

[2]  Dudley H. Williams,et al.  The N-linked oligosaccharides of aminopeptidase N from Manduca sexta: site localization and identification of novel N-glycan structures. , 2004, European journal of biochemistry.

[3]  K. Matsumura,et al.  Detection of O-mannosyl glycans in rabbit skeletal muscle α-dystroglycan , 1998 .

[4]  F. Hanisch,et al.  O-Glycosylation of the Mucin Type , 2001, Biological chemistry.

[5]  Y. C Lee,et al.  Carbohydrate analyses with high-performance anion-exchange chromatography , 1996 .

[6]  T. Hayakawa,et al.  Comparative studies on the analysis of glycosylation heterogeneity of sialic acid-containing glycoproteins using capillary electrophoresis. , 2000, Journal of chromatography. A.

[7]  R. Geyer,et al.  Identification and Characterization of Keyhole Limpet Hemocyanin N-Glycans Mediating Cross-reactivity with Schistosoma mansoni* , 2005, Journal of Biological Chemistry.

[8]  A. Helenius,et al.  Roles of N-linked glycans in the endoplasmic reticulum. , 2004, Annual review of biochemistry.

[9]  Y. Mechref,et al.  Semiautomated high-sensitivity profiling of human blood serum glycoproteins through lectin preconcentration and multidimensional chromatography/tandem mass spectrometry. , 2006, Journal of proteome research.

[10]  G. Lamblin,et al.  The glycosylation of airway mucins in cystic fibrosis and its relationship with lung infection by Pseudomonas aeruginosa. , 2003, Advances in experimental medicine and biology.

[11]  A. Suzuki,et al.  Convenient and rapid analysis of linkage isomers of fucose-containing oligosaccharides by matrix-assisted laser desorption/ionization quadrupole ion trap time-of-flight mass spectrometry , 2005, Glycoconjugate Journal.

[12]  Stephen A. Martin,et al.  Delayed extraction matrix‐assisted laser desorption time‐of‐flight mass spectrometry , 1995 .

[13]  L. Wells,et al.  Comprehensive glycan analysis of recombinant Aspergillus niger endo-polygalacturonase C. , 2006, Analytical biochemistry.

[14]  M. Kostrzewa,et al.  Selective isolation of glycoproteins and glycopeptides for MALDI-TOF MS detection supported by magnetic particles. , 2005, Journal of biomolecular techniques : JBT.

[15]  J. Blein,et al.  Proteomics of Plant Detergent-resistant Membranes * S , 2006, Molecular & Cellular Proteomics.

[16]  K. Anumula,et al.  Advances in fluorescence derivatization methods for high-performance liquid chromatographic analysis of glycoprotein carbohydrates. , 2006, Analytical biochemistry.

[17]  C. Hellerqvist.  Linkage analysis using Lindberg method. , 1990, Methods in enzymology.

[18]  R. Dwek,et al.  Fast sequencing of oligosaccharides: the reagent-array analysis method. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[19]  J. Paulson,et al.  Glycomics: an integrated systems approach to structure-function relationships of glycans , 2005, Nature Methods.

[20]  R Apweiler,et al.  On the frequency of protein glycosylation, as deduced from analysis of the SWISS-PROT database. , 1999, Biochimica et biophysica acta.

[21]  D. Harvey,et al.  Electrospray ionization-ion trap mass spectrometry for structural analysis of complex N-linked glycoprotein oligosaccharides. , 1998, Analytical chemistry.

[22]  Albert Sickmann,et al.  Laser-induced dissociation/high-energy collision-induced dissociation fragmentation using MALDI-TOF/TOF-MS instrumentation for the analysis of neutral and acidic oligosaccharides. , 2005, Analytical chemistry.

[23]  W. Whelan,et al.  Glycogenin: the primer for mammalian and yeast glycogen synthesis. , 2004, Biochimica et biophysica acta.

[24]  Y. Mechref,et al.  Microscale nonreductive release of O-linked glycans for subsequent analysis through MALDI mass spectrometry and capillary electrophoresis. , 2001, Analytical chemistry.

[25]  T. Tsuji,et al.  Fractionation and structural assessment of oligosaccharides and glycopeptides by use of immobilized lectins. , 1987, Annual review of biochemistry.

[26]  Yehia Mechref,et al.  Combining lectin microcolumns with high-resolution separation techniques for enrichment of glycoproteins and glycopeptides. , 2005, Analytical chemistry.

[27]  N. Otsuki,et al.  Novel Proteoglycan Linkage Tetrasaccharides of Human Urinary Soluble Thrombomodulin, SO4-3GlcAβ1–3Galβ1–3(±Siaα2–6)Galβ1–4Xyl* , 1999, The Journal of Biological Chemistry.

[28]  F. Regnier,et al.  Proteomics of glycoproteins based on affinity selection of glycopeptides from tryptic digests. , 2001, Journal of chromatography. B, Biomedical sciences and applications.

[29]  H. Ikezawa,et al.  Glycosylphosphatidylinositol (GPI)-anchored proteins. , 2002, Biological & pharmaceutical bulletin.

[30]  R. O'neill.  Enzymatic release of oligosaccharides from glycoproteins for chromatographic and electrophoretic analysis. , 1996, Journal of chromatography. A.

[31]  N. Sharon,et al.  Lectins as cell recognition molecules. , 1989, Science.

[32]  W. Kisiel,et al.  Identification of a disaccharide (Xyl-Glc) and a trisaccharide (Xyl2-Glc) O-glycosidically linked to a serine residue in the first epidermal growth factor-like domain of human factors VII and IX and protein Z and bovine protein Z. , 1989, The Journal of biological chemistry.

[33]  G. Evjen,et al.  Site-specific glycosylation analysis of the bovine lysosomal α-mannosidase , 2006 .

[34]  Y. Mechref,et al.  New hyphenated methodologies in high-sensitivity glycoprotein analysis. , 2005, Journal of separation science.

[35]  Raymond A Dwek,et al.  Conformational studies of oligosaccharides and glycopeptides: complementarity of NMR, X-ray crystallography, and molecular modelling. , 2002, Chemical reviews.

[36]  T. Pritchett,et al.  Capillary gel electrophoresis separation of high‐mannose type oligosaccharides derivatized by 1‐aminopyrene‐3,6,8‐trisulfonic acid , 1995, Electrophoresis.

[37]  Niclas G Karlsson,et al.  Development of a mass fingerprinting tool for automated interpretation of oligosaccharide fragmentation data , 2004, Proteomics.

[38]  R. Geyer,et al.  Saccharide linkage analysis using methylation and other techniques. , 1994, Methods in enzymology.

[39]  M. Jovanović,et al.  Glycoprotein identification and localization of O-glycosylation sites by mass spectrometric analysis of deglycosylated/alkylaminylated peptide fragments. , 2001, Analytical biochemistry.

[40]  W. Hancock,et al.  Approaches to the study of N-linked glycoproteins in human plasma using lectin affinity chromatography and nano-HPLC coupled to electrospray linear ion trap--Fourier transform mass spectrometry. , 2006, Glycobiology.

[41]  R. U. Margolis,et al.  High prevalence of 2-mono- and 2,6-di-substituted manol-terminating sequences among O-glycans released from brain glycopeptides by reductive alkaline hydrolysis. , 1999, European journal of biochemistry.

[42]  S. Ficarro,et al.  Exploring the O-GlcNAc proteome: direct identification of O-GlcNAc-modified proteins from the brain. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[43]  A. Deelder,et al.  Oligosaccharide analysis by capillary-scale high-pH anion-exchange chromatography with on-line ion-trap mass spectrometry. , 2005, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

[44]  Y. Mechref,et al.  Mass spectrometric mapping and sequencing of N-linked oligosaccharides derived from submicrogram amounts of glycoproteins. , 1998, Analytical chemistry.

[45]  Richard D Cummings,et al.  Altered O-glycosylation and sulfation of airway mucins associated with cystic fibrosis. , 2005, Glycobiology.

[46]  Jakob Bunkenborg,et al.  A new strategy for identification of N-glycosylated proteins and unambiguous assignment of their glycosylation sites using HILIC enrichment and partial deglycosylation. , 2004, Journal of proteome research.

[47]  Dudley H. Williams,et al.  Fragmentation characteristics of neutral N-linked glycans using a MALDI-TOF/TOF tandem mass spectrometer. , 2004, Analytical chemistry.

[48]  J. Hirabayashi.  Lectin-based structural glycomics: Glycoproteomics and glycan profiling , 2004, Glycoconjugate Journal.

[49]  Ron A Wevers,et al.  Mechanisms in protein O-glycan biosynthesis and clinical and molecular aspects of protein O-glycan biosynthesis defects: a review. , 2006, Clinical chemistry.

[50]  Friedrich Altmann,et al.  Peptide‐N4‐(N‐acetyl‐β‐glucosaminyl)asparagine amidase F cannot release glycans with fucose attached α1 → 3 to the asparagine‐linked N‐acetylglucosamine residue , 1991 .

[51]  G. Strecker,et al.  Gas--liquid chromatography and mass spectrometry of methylated and acetylated methyl glycosides. Application to the structural analysis of glycoprotein glycans. , 1981, Analytical biochemistry.

[52]  A. Haselbeck,et al.  Immunological detection of glycoproteins on blots based on labeling with digoxigenin. , 1993, Methods in molecular biology.

[53]  Y. Wada,et al.  Derivatization for stabilizing sialic acids in MALDI-MS. , 2005, Analytical chemistry.

[54]  R. Geyer,et al.  An optimized protocol for nano-LC-MALDI-TOF-MS coupling for the analysis of proteolytic digests of glycoproteins. , 2004, Biomedical chromatography : BMC.

[55]  D. Ashline,et al.  Congruent strategies for carbohydrate sequencing. 1. Mining structural details by MSn. , 2005, Analytical chemistry.

[56]  S. Hakomori,et al.  [2] Microscale methylation analysis of glycolipids using capillary gas chromatography-chemical ionization mass fragmentography with selected ion monitoring , 1987 .

[57]  J. Roth.  Protein N-glycosylation along the secretory pathway: relationship to organelle topography and function, protein quality control, and cell interactions. , 2002, Chemical reviews.

[58]  T. Takao,et al.  N‐glycosylation at Asn491 in the Asn‐Xaa‐Cys motif of human transferrin , 2004, FEBS letters.

[59]  M. Tajiri,et al.  Hydrophilic affinity isolation and MALDI multiple-stage tandem mass spectrometry of glycopeptides for glycoproteomics. , 2004, Analytical chemistry.

[60]  M F Bean,et al.  Collisional fragmentation of glycopeptides by electrospray ionization LC/MS and LC/MS/MS: methods for selective detection of glycopeptides in protein digests. , 1993, Analytical chemistry.

[61]  D. Ashline,et al.  Congruent strategies for carbohydrate sequencing. 3. OSCAR: an algorithm for assigning oligosaccharide topology from MSn data. , 2005, Analytical chemistry.

[62]  A. Ulmer,et al.  Structural Elucidation and Monokine-inducing Activity of Two Biologically Active Zwitterionic Glycosphingolipids Derived from the Porcine Parasitic Nematode Ascaris suum * , 1998, The Journal of Biological Chemistry.

[63]  H. Desaire,et al.  Glycoprotein profiling by electrospray mass spectrometry , 2004, Journal of the American Society for Mass Spectrometry.

[64]  R. Parekh,et al.  Nonselective and efficient fluorescent labeling of glycans using 2-amino benzamide and anthranilic acid. , 1995, Analytical biochemistry.

[65]  V. Reinhold,et al.  Structural characterization of carbohydrate sequence, linkage, and branching in a quadrupole Ion trap mass spectrometer: neutral oligosaccharides and N-linked glycans. , 1998, Analytical chemistry.

[66]  R. Geyer,et al.  Structural analysis of glycoconjugates by on-target enzymatic digestion and MALDI-TOF-MS. , 1999, Analytical chemistry.

[67]  W. Michalski.  The Mass Spectrometric Analysis of Glycoproteins and their Glycan Structures , 2005 .

[68]  D. Segal,et al.  Multiple Dimeric Forms of Human CD69 Result from Differential Addition of N-Glycans to Typical (Asn-X-Ser/Thr) and Atypical (Asn-X-Cys) Glycosylation Motifs* , 1997, The Journal of Biological Chemistry.

[69]  P. Vouros,et al.  Liquid chromatography ion trap mass spectrometric analysis of oligosaccharides using permethylated derivatives. , 2001, Rapid communications in mass spectrometry : RCM.

[70]  R. Orlando,et al.  Tools for glycoproteomic analysis: size exclusion chromatography facilitates identification of tryptic glycopeptides with N-linked glycosylation sites. , 2006, Journal of proteome research.

[71]  C. Fenselau,et al.  Lectin and carbohydrate affinity capture surfaces for mass spectrometric analysis of microorganisms. , 2001, Analytical chemistry.

[72]  J. Markl,et al.  Hemocyanin from the keyhole limpet Megathura crenulata (KLH) carries a novel type of N-glycans with Gal(beta1-6)Man-motifs. , 2002, European journal of biochemistry.

[73]  R. Dwek,et al.  Oligosaccharide sequencing technology , 1997, Nature.

[74]  T. Hayakawa,et al.  Characterization of a gel-separated unknown glycoprotein by liquid chromatography/multistage tandem mass spectrometry: analysis of rat brain Thy-1 separated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. , 2005, Journal of chromatography. A.

[75]  Yingming Zhao,et al.  Tagging-via-substrate strategy for probing O-GlcNAc modified proteins. , 2005, Journal of proteome research.

[76]  Niclas G Karlsson,et al.  Small-scale analysis of O-linked oligosaccharides from glycoproteins and mucins separated by gel electrophoresis. , 2002, Analytical chemistry.

[77]  Hiroaki Nakagawa,et al.  High Throughput Quantitative Glycomics and Glycoform-focused Proteomics of Murine Dermis and Epidermis* , 2005, Molecular & Cellular Proteomics.

[78]  T. Takao,et al.  Human factor IX has a tetrasaccharide O-glycosidically linked to serine 61 through the fucose residue. , 1992, The Journal of biological chemistry.

[79]  W. Hancock,et al.  Approach to the comprehensive analysis of glycoproteins isolated from human serum using a multi-lectin affinity column. , 2004, Journal of chromatography. A.

[80]  J. Kamerling,et al.  Gas-Liquid Chromatography and Mass Spectrometry of Sialic Acids , 1982 .

[81]  S. Hase,et al.  Analysis of pyridylaminated O-linked sugar chains by two-dimensional sugar mapping. , 1996, Analytical biochemistry.

[82]  R. Dwek,et al.  Analytical and preparative separation of anionic oligosaccharides by weak anion-exchange high-performance liquid chromatography on an inert polymer column. , 1994, Analytical biochemistry.

[83]  A. Casadevall,et al.  Site-specific characterization of the N-linked oligosaccharides of a murine immunoglobulin M by high-performance liquid chromatography/electrospray mass spectrometry. , 2003, Analytical biochemistry.

[84]  G. J. Rademaker,et al.  Mass spectrometric determination of the sites of O-glycan attachment with low picomolar sensitivity. , 1998, Analytical biochemistry.

[85]  U. Bahr,et al.  Structural elucidation of zwitterionic carbohydrates derived from glycosphingolipids of the porcine parasitic nematode Ascaris suum. , 2003, The Biochemical journal.

[86]  André M Deelder,et al.  Protein glycosylation analysis by liquid chromatography-mass spectrometry. , 2005, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

[87]  T. Masuko,et al.  Capillary electrophoresis of sialic acid-containing glycoprotein. Effect of the heterogeneity of carbohydrate chains on glycoform separation using an alpha1-acid glycoprotein as a model. , 2001, Analytical chemistry.

[88]  F. Regnier,et al.  Use of a lectin affinity selector in the search for unusual glycosylation in proteomics. , 2002, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

[89]  R. Geyer,et al.  Structure elucidation of sulphated oligosaccharides from recombinant human tissue plasminogen activator expressed in mouse epithelial cells. , 1992, Glycobiology.

[90]  R. Dwek,et al.  Comparison of the N-linked glycans from soluble and GPI-anchored CD59 expressed in CHO cells. , 2002, Glycobiology.

[91]  K. Yamamoto,et al.  Analysis of asparagine-linked oligosaccharides by sequential lectin affinity chromatography. , 1995, Molecular biotechnology.

[92]  J. Lo-Guidice,et al.  Human airway mucin glycosylation: A combinatory of carbohydrate determinants which vary in cystic fibrosis , 2001, Glycoconjugate Journal.

[93]  A. Jones,et al.  Analysis of acidic oligosaccharides and glycopeptides by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. , 1996, Analytical chemistry.

[94]  M. Schachner,et al.  Localization of defined carbohydrate epitopes in bovine polysialylated NCAM. , 2003, Biochimie.

[95]  A. Deelder,et al.  New features of site-specific horseradish peroxidase (HRP) glycosylation uncovered by nano-LC-MS with repeated ion-isolation/fragmentation cycles. , 2005, Biochimica et biophysica acta.

[96]  B. Domon,et al.  Capillary electrophoresis/electrospray ion trap mass spectrometry for the analysis of negatively charged derivatized and underivatized glycans. , 2002, Rapid communications in mass spectrometry : RCM.

[97]  C. Chiesa,et al.  Capillary zone electrophoresis of oligosaccharides derivatized with various aminonaphthalene sulfonic acids , 1994, Electrophoresis.

[98]  J. Peter-Katalinic,et al.  Electron Capture Dissociation of O-Glycosylated Peptides: Radical Site-Induced Fragmentation of Glycosidic Bonds , 2005, European journal of mass spectrometry.

[99]  M. Nakano,et al.  Rapid and sensitive screening of N-glycans as 9-fluorenylmethyl derivatives by high-performance liquid chromatography: a method which can recover free oligosaccharides after analysis. , 2005, Journal of proteome research.

[100]  T. Hayakawa,et al.  Specific detection of Lewis x-carbohydrates in biological samples using liquid chromatography/multiple-stage tandem mass spectrometry. , 2005, Rapid communications in mass spectrometry : RCM.

[101]  T. Hayakawa,et al.  Site-specific N-glycosylation analysis of human plasma ceruloplasmin using liquid chromatography with electrospray ionization tandem mass spectrometry. , 2006, Analytical biochemistry.

[102]  J. Duus,et al.  Carbohydrate structural determination by NMR spectroscopy: modern methods and limitations. , 2000, Chemical reviews.

[103]  Hailong Zhang,et al.  Congruent strategies for carbohydrate sequencing. 2. FragLib: an MSn spectral library. , 2005, Analytical chemistry.

[104]  H Kaltner,et al.  Lectin Ligands: New Insights into Their Conformations and Their Dynamic Behavior and the Discovery of Conformer Selection by Lectins , 1998, Cells Tissues Organs.

[105]  H. Perreault,et al.  Site‐specific N‐glycosylation analysis: matrix‐assisted laser desorption/ionization quadrupole‐quadrupole time‐of‐flight tandem mass spectral signatures for recognition and identification of glycopeptides , 2004, Rapid communications in mass spectrometry : RCM.

[106]  A. Helenius,et al.  Intracellular functions of N-linked glycans. , 2001, Science.

[107]  A. Deelder,et al.  Protein glycosylation analyzed by normal-phase nano-liquid chromatography--mass spectrometry of glycopeptides. , 2005, Analytical chemistry.

[108]  J. Peter-Katalinic,et al.  Localization of O-glycosylation sites of MUC1 tandem repeats by QTOF ESI mass spectrometry. , 1998, Journal of mass spectrometry : JMS.

[109]  M. Karas,et al.  Structural analysis of underivatized neutral human milk oligosaccharides in the negative ion mode by nano-electrospray MSn (Part 1: Methodology) , 2002, Journal of the American Society for Mass Spectrometry.

[110]  C. Gahmberg,et al.  Structural study of N-linked oligosaccharides of human intercellular adhesion molecule-3 (CD50). , 2001, European journal of biochemistry.

[111]  H. Gabius,et al.  Carbohydrate–Protein Interaction , 2008 .

[112]  A G Marshall,et al.  Electron capture dissociation and infrared multiphoton dissociation MS/MS of an N-glycosylated tryptic peptic to yield complementary sequence information. , 2001, Analytical chemistry.

[113]  Reed J. Harris,et al.  O-linked fucose and other post-translational modifications unique to EGF modules. , 1993, Glycobiology.

[114]  T. Hayakawa,et al.  Analysis of carbohydrate heterogeneity in a glycoprotein using liquid chromatography/mass spectrometry and liquid chromatography with tandem mass spectrometry. , 1999, Analytical biochemistry.

[115]  G. Hart,et al.  O-GlcNAc a sensor of cellular state: the role of nucleocytoplasmic glycosylation in modulating cellular function in response to nutrition and stress. , 2004, Biochimica et biophysica acta.

[116]  R. Cummings,et al.  Fractionation of asparagine-linked oligosaccharides by serial lectin-Agarose affinity chromatography. A rapid, sensitive, and specific technique. , 1982, The Journal of biological chemistry.

[117]  D. Chelius,et al.  Characterization of protein glycosylation using chip-based infusion nanoelectrospray linear ion trap tandem mass spectrometry. , 2004, Journal of biomolecular techniques : JBT.

[118]  Pauline M Rudd,et al.  An analytical and structural database provides a strategy for sequencing O-glycans from microgram quantities of glycoproteins. , 2002, Analytical biochemistry.

[119]  A. Kuno,et al.  Evanescent-field fluorescence-assisted lectin microarray: a new strategy for glycan profiling , 2005, Nature Methods.

[120]  M. Wiener,et al.  A lectin screening method for membrane glycoproteins: application to the human CHIP28 water channel (AQP-1). , 1996, Analytical biochemistry.

[121]  David J Harvey,et al.  Proteomic analysis of glycosylation: structural determination of N- and O-linked glycans by mass spectrometry , 2005, Expert review of proteomics.

[122]  A. Deelder,et al.  Nano-scale liquid chromatography-mass spectrometry of 2-aminobenzamide-labeled oligosaccharides at low femtomole sensitivity , 2004 .

[123]  D. Tulsiani.  Structural analysis of the asparagine-linked glycan units of the ZP2 and ZP3 glycoproteins from mouse zona pellucida. , 2000, Archives of biochemistry and biophysics.

[124]  Yehia Mechref,et al.  Structural investigations of glycoconjugates at high sensitivity. , 2002, Chemical reviews.

[125]  B K Hayes,et al.  Selective detection and site-analysis of O-GlcNAc-modified glycopeptides by beta-elimination and tandem electrospray mass spectrometry. , 1996, Analytical biochemistry.

[126]  M. Schachner,et al.  Core structures of polysialylated glycans present in neural cell adhesion molecule from newborn mouse brain. , 2001, European journal of biochemistry.

[127]  E. Gaucher,et al.  Cytoplasmic glycosylation of protein-hydroxyproline and its relationship to other glycosylation pathways. , 2004, Biochimica et biophysica acta.

[128]  M. F. Bean,et al.  Selective identification and differentiation of N‐and O‐linked oligosaccharides in glycoproteins by liquid chromatography‐mass spectrometry , 1993, Protein science : a publication of the Protein Society.

[129]  H. Anttinen,et al.  Regulation of the glycosylations of collagen hydroxylysine in chick embryo tendon and cartilage cells. , 1980, Biochimica et biophysica acta.

[130]  A. Varki,et al.  Biological roles of oligosaccharides: all of the theories are correct , 1993, Glycobiology.

[131]  R. Dwek,et al.  A rapid high-resolution high-performance liquid chromatographic method for separating glycan mixtures and analyzing oligosaccharide profiles. , 1996, Analytical biochemistry.

[132]  A. Dell,et al.  Differential O-glycosylation of a conserved domain expressed in murine and human ZP3. , 2006, Biochemistry.

[133]  Carolyn R Bertozzi,et al.  The chemistry and biology of mucin-type O-linked glycosylation. , 2005, Bioorganic & medicinal chemistry.

[134]  J. Peter-Katalinic,et al.  Characterization of O-glycosylation sites in MUC2 glycopeptides by nanoelectrospray QTOF mass spectrometry. , 1999, Journal of mass spectrometry : JMS.

[135]  Hans-Joachim Gabius,et al.  Glycosciences: Status and Perspectives , 2002 .

[136]  K. Medzihradszky.  Characterization of protein N-glycosylation. , 2005, Methods in enzymology.

[137]  J. Hirabayashi,et al.  Separation technologies for glycomics. , 2002, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

[138]  P. Derrick,et al.  Electrospray ionization fourier transform ion cyclotron resonance mass spectrometry of human alpha-1-acid glycoprotein. , 2004, Analytical chemistry.

[139]  T. Endo.  O-mannosyl glycans in mammals. , 1999, Biochimica et biophysica acta.

[140]  J. Vliegenthart,et al.  High-Resolution, 1H-Nuclear Magnetic Resonance Spectroscopy as a Tool in the Structural Analysis of Carbohydrates Related to Glycoproteins , 1983 .

[141]  James Paulson,et al.  Automatic annotation of matrix‐assisted laser desorption/ionization N‐glycan spectra , 2005, Proteomics.

[142]  K. Stulík,et al.  Effects of electrolyte modification and capillary coating on separation of glycoprotein isoforms by capillary electrophoresis , 2001, Electrophoresis.

[143]  R. Cummings,et al.  Use of lectins in analysis of glycoconjugates. , 1994, Methods in enzymology.

[144]  M. Novotny,et al.  Hydrolytically stable cellulose‐derivative coatings for capillary electrophoresis of peptides, proteins and glycoconjugates , 1995, Electrophoresis.

[145]  Michiko Tajiri,et al.  Differential analysis of site-specific glycans on plasma and cellular fibronectins: application of a hydrophilic affinity method for glycopeptide enrichment. , 2005, Glycobiology.

[146]  J. Peter-Katalinic,et al.  Methods in enzymology: O-glycosylation of proteins. , 2005, Methods in enzymology.

[147]  B. Domon,et al.  Structural analysis of permethylated oligosaccharides by electrospray tandem mass spectrometry. , 1997, Analytical chemistry.

[148]  G. Hart,et al.  O‐GlcNAc cycling: How a single sugar post‐translational modification is changing the Way We think about signaling networks , 2006, Journal of cellular biochemistry.

[149]  Frank Kjeldsen,et al.  Complete characterization of posttranslational modification sites in the bovine milk protein PP3 by tandem mass spectrometry with electron capture dissociation as the last stage. , 2003, Analytical chemistry.

[150]  S. Nishimura,et al.  Structural characterization of N-glycopeptides by matrix-dependent selective fragmentation of MALDI-TOF/TOF tandem mass spectrometry. , 2004, Analytical chemistry.

[151]  M. Green,et al.  High-energy collision-induced fragmentation of complex oligosaccharides ionized by matrix-assisted laser desorption/ionization mass spectrometry. , 1997, Journal of mass spectrometry : JMS.

[152]  Lance Wells,et al.  Mapping Sites of O-GlcNAc Modification Using Affinity Tags for Serine and Threonine Post-translational Modifications* , 2002, Molecular & Cellular Proteomics.

[153]  R. Spiro.  Protein glycosylation: nature, distribution, enzymatic formation, and disease implications of glycopeptide bonds. , 2002, Glycobiology.

[154]  Ruedi Aebersold,et al.  Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry , 2003, Nature Biotechnology.

[155]  P. Thibault,et al.  Identification of unusual bacterial glycosylation by tandem mass spectrometry analyses of intact proteins. , 2005, Analytical chemistry.

[156]  W. Gerlich,et al.  Structure of pre-S2 N- and O-linked glycans in surface proteins from different genotypes of hepatitis B virus. , 2004, The Journal of general virology.

[157]  Albert Sickmann,et al.  Challenges in mass spectrometry‐based proteomics , 2004, Proteomics.

[158]  F. Hanisch.  Methylation analysis of complex carbohydrates: overview and critical comments. , 1994, Biological mass spectrometry.

[159]  Wei Sun,et al.  Concanavalin A-captured Glycoproteins in Healthy Human Urine *S , 2006, Molecular & Cellular Proteomics.

[160]  T. Hayakawa,et al.  Selective glycopeptide mapping of erythropoietin by on-line high-performance liquid chromatography--electrospray ionization mass spectrometry. , 2001, Journal of chromatography. A.

[161]  Rahul Raman,et al.  Structural insights into biological roles of protein-glycosaminoglycan interactions. , 2005, Chemistry & biology.

[162]  Scott A McLuckey,et al.  Complementary structural information from a tryptic N-linked glycopeptide via electron transfer ion/ion reactions and collision-induced dissociation. , 2005, Journal of proteome research.

[163]  Y. Mechref,et al.  Matrix-assisted laser desorption/ionization mass spectrometry compatible beta-elimination of O-linked oligosaccharides. , 2002, Rapid communications in mass spectrometry : RCM.

[164]  Raymond A. Dwek,et al.  Glycobiology: Toward Understanding the Function of Sugars. , 1996, Chemical reviews.

[165]  J. Zaia.  Mass spectrometry of oligosaccharides. , 2004, Mass spectrometry reviews.

[166]  J. Peter-Katalinic,et al.  Glycoproteomics of N‐glycosylation by in‐gel deglycosylation and matrix‐assisted laser desorption/ionisation‐time of flight mass spectrometry mapping: Application to congenital disorders of glycosylation , 2005, Proteomics.

[167]  C. Sottani,et al.  Preliminary investigation of glycosylated proteins by capillary electrophoresis and capillary electrophoresis/mass spectrometry using electrospray ionization and by matrix-assisted laser desorption ionization/time-to-flight mass spectrometry. , 1995, Rapid communications in mass spectrometry : RCM.

[168]  Sumihiro Hase,et al.  Precolumn derivatization for chromatographic and electrophoretic analyses of carbohydrates , 1996 .

[169]  W. G. Kelly,et al.  Glycosylation in the nucleus and cytoplasm. , 1989, Annual review of biochemistry.

[170]  J. Hirabayashi,et al.  Lectin affinity capture, isotope-coded tagging and mass spectrometry to identify N-linked glycoproteins , 2003, Nature Biotechnology.

[171]  N. Packer,et al.  Sequential analysis of N- and O-linked glycosylation of 2D-PAGE separated glycoproteins. , 2002, Journal of proteome research.

[172]  K. Niikura,et al.  Direct N-glycan profiling in the presence of tryptic peptides on MALDI-TOF by controlled ion enhancement and suppression upon glycan-selective derivatization. , 2004, Analytical chemistry.

[173]  Fu-Tai A. Chen,et al.  Separation of 1‐aminopyrene‐3,6,8‐trisulfonate‐labeled asparagine‐linked fetuin glycans by capillary gel electrophoresis , 1996, Electrophoresis.

[174]  W. Hancock,et al.  Monitoring glycosylation pattern changes of glycoproteins using multi-lectin affinity chromatography. , 2005, Journal of chromatography. A.

[175]  J. Kamerling,et al.  A strategy for the mapping of N-glycans by high-performance capillary electrophoresis. , 1994, Analytical biochemistry.

[176]  M. Ferguson,et al.  The structure, biosynthesis and functions of glycosylphosphatidylinositol anchors, and the contributions of trypanosome research. , 1999, Journal of cell science.

[177]  D. Harvey.  Structural determination of N‐linked glycans by matrix‐assisted laser desorption/ionization and electrospray ionization mass spectrometry , 2005, Proteomics.

[178]  T. Annesley.  Ion suppression in mass spectrometry. , 2003, Clinical chemistry.

[179]  R. Zahedi,et al.  Two‐dimensional benzyldimethyl‐n‐hexadecylammonium chloride/SDS‐PAGE for membrane proteomics , 2005, Proteomics.

[180]  Toshihiko Oka,et al.  Oligosaccharide specificity of galectins: a search by frontal affinity chromatography. , 2002, Biochimica et biophysica acta.

[181]  Chong Yu,et al.  A metabolic labeling approach toward proteomic analysis of mucin-type O-linked glycosylation , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[182]  A. Deelder,et al.  Normal-phase nanoscale liquid chromatography-mass spectrometry of underivatized oligosaccharides at low-femtomole sensitivity. , 2004, Analytical chemistry.

[183]  D. Harvey,et al.  Stabilization of sialic acids in N-linked oligosaccharides and gangliosides for analysis by positive ion matrix-assisted laser desorption/ionization mass spectrometry. , 1996, Rapid communications in mass spectrometry : RCM.

[184]  N. Smalheiser,et al.  Structural Analysis of Sequences O-Linked to Mannose Reveals a Novel Lewis X Structure in Cranin (Dystroglycan) Purified from Sheep Brain* , 1998, The Journal of Biological Chemistry.

[185]  P M Rudd,et al.  A high‐performance liquid chromatography based strategy for rapid, sensitive sequencing of N‐linked oligosaccharide modifications to proteins in sodium dodecyl sulphate polyacrylamide electrophoresis gel bands , 2001, Proteomics.

[186]  M. Wilm,et al.  Analytical properties of the nanoelectrospray ion source. , 1996, Analytical chemistry.

[187]  Manfred Nimtz,et al.  Sequencing of tri- and tetraantennary N-glycans containing sialic acid by negative mode ESI QTOF tandem MS , 2002, Journal of the American Society for Mass Spectrometry.

[188]  O. J. Semmes,et al.  Lectin Capture Strategies Combined with Mass Spectrometry for the Discovery of Serum Glycoprotein Biomarkers* , 2006, Molecular & Cellular Proteomics.

[189]  J. Lowe,et al.  Role of glycosylation in development. , 2003, Annual review of biochemistry.

[190]  O Hindsgaul,et al.  Rapid determination of the binding affinity and specificity of the mushroom Polyporus squamosus lectin using frontal affinity chromatography coupled to electrospray mass spectrometry. , 2001, Glycobiology.

[191]  G. Hart,et al.  The emerging significance of O-GlcNAc in cellular regulation. , 2002, Chemical reviews.

[192]  H. Steen,et al.  Using optimized collision energies and high resolution, high accuracy fragment ion selection to improve glycopeptide detection by precursor ion scanning , 2003, Journal of the American Society for Mass Spectrometry.

[193]  B. Domon,et al.  A systematic nomenclature for carbohydrate fragmentations in FAB-MS/MS spectra of glycoconjugates , 1988, Glycoconjugate Journal.

[194]  S. Brunak,et al.  Prediction, conservation analysis, and structural characterization of mammalian mucin-type O-glycosylation sites. , 2005, Glycobiology.

[195]  Y. Mechref,et al.  High-sensitivity profiling of glycoproteins from human blood serum through multiple-lectin affinity chromatography and liquid chromatography/tandem mass spectrometry. , 2007, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

[196]  Hyun Joo An,et al.  Determination of N-glycosylation sites and site heterogeneity in glycoproteins. , 2003, Analytical chemistry.

[197]  T. Endo.  Fractionation of glycoprotein-derived oligosaccharides by affinity chromatography using immobilized lectin columns. , 1996, Journal of chromatography. A.

[198]  J. Michalski,et al.  Electrospray ionization ion trap mass spectrometry for structural characterization of oligosaccharides derivatized with 2-aminobenzamide. , 2005, Rapid communications in mass spectrometry : RCM.

[199]  P. Stanley,et al.  Modulation of receptor signaling by glycosylation: fringe is an O-fucose-beta1,3-N-acetylglucosaminyltransferase. , 2002, Biochimica et biophysica acta.

[200]  M. Zehl,et al.  Determination of glycopeptide structures by multistage mass spectrometry with low-energy collision-induced dissociation: comparison of electrospray ionization quadrupole ion trap and matrix-assisted laser desorption/ionization quadrupole ion trap reflectron time-of-flight approaches. , 2004, Rapid communications in mass spectrometry : RCM.

[201]  J. Peter-Katalinic,et al.  Analysis of the Pre-S2 N- and O-Linked Glycans of the M Surface Protein from Human Hepatitis B Virus* , 1999, The Journal of Biological Chemistry.

[202]  A. Freas,et al.  Analysis of viral glycoproteins by MALDI-TOF mass spectrometry. , 2001, Analytical chemistry.

[203]  Yehia Mechref,et al.  Structural characterization of oligosaccharides using MALDI-TOF/TOF tandem mass spectrometry. , 2003, Analytical chemistry.

[204]  Fu-Tai A. Chen,et al.  Profiling glycoprotein N‐linked oligosaccharide by capillary electrophoresis , 1998, Electrophoresis.

[205]  B. Küster,et al.  Glycosylation analysis of gel‐separated proteins , 2001, Proteomics.

[206]  C. Minoia,et al.  Matrix performance in matrix-assisted laser desorption/ionization for molecular weight determination in sialyl and non-sialyl oligosaccharide proteins. , 1997, Rapid communications in mass spectrometry : RCM.

[207]  A. Deelder,et al.  Glycopeptide analysis by matrix-assisted laser desorption/ionization tandem time-of-flight mass spectrometry reveals novel features of horseradish peroxidase glycosylation. , 2004, Rapid communications in mass spectrometry : RCM.

[208]  T. Dillon,et al.  Development of an analytical reversed-phase high-performance liquid chromatography-electrospray ionization mass spectrometry method for characterization of recombinant antibodies. , 2004, Journal of chromatography. A.