User-centered design techniques for a computerised antibiotic decision support system in an intensive care unit

OBJECTIVE To explore the use of user-centered design techniques for developing the requirements for an antibiotic decision support system (DSS) in an intensive care unit (ICU). DESIGN AND METHODOLOGY The setting was a 21-bed mixed medical/surgical adult ICU. This was an observational study with unstructured interviews and participatory design process. Models were constructed to demonstrate cultural, workflow, sequence/trigger events and other artefacts used to support antibiotic prescribing in the ICU. Using participatory design, a paper prototype was developed and case studies were used to simulate antibiotic prescribing for bacterial isolates. This information was used to design and pilot the decision support tool. RESULTS The key users were identified as residents, registrars and the unit pharmacist. They identified the major requirements: ability to collate and print microbiology results, and to provide education and antibiotic advice for isolates. The final product was a real time microbiology browser and decision support tool for antibiotic prescribing (ADVISE). Uptake of the system was rapid with over 6000 encounters in the first 6 months. An audit of antibiotic use performed on all consecutive patients 6 months before and after introducing the DSS demonstrated a reduction in total and broad-spectrum antibiotics. CONCLUSION Contextual design methodology in conjunction with participatory design was an effective method to design this antibiotic decision support tool. The process facilitated physician and pharmacist ownership of the system that resulted in immediate uptake and ongoing use.

[1]  John M. Carroll Human-computer interaction: psychology as a science of design. , 1997 .

[2]  Jakob Nielsen,et al.  Estimating the number of subjects needed for a thinking aloud test , 1994, Int. J. Hum. Comput. Stud..

[3]  David Campany,et al.  Monitoring of Antimicrobial therapy by an integrated computer program , 1999, Pharmacy World and Science.

[4]  Rebecca S. Crowley,et al.  Using Contextual Design to Identify Potential Innovations for Problem Based Learning , 2003, AMIA.

[5]  M. Richards,et al.  Impact of a web‐based antimicrobial approval system on broad‐spectrum cephalosporin use at a teaching hospital , 2003, The Medical journal of Australia.

[6]  T. Clemmer,et al.  A computer-assisted management program for antibiotics and other antiinfective agents. , 1998, The New England journal of medicine.

[7]  R M Gardner,et al.  Improved perioperative antibiotic use and reduced surgical wound infections through use of computer decision analysis. , 1989, Infection control and hospital epidemiology.

[8]  R. Haynes,et al.  Effects of computer-based clinical decision support systems on physician performance and patient outcomes: a systematic review. , 1998, JAMA.

[9]  Wendy Chan,et al.  Increasing the success of physician order entry through human factors engineering. , 2002, Journal of healthcare information management : JHIM.

[10]  C R Doarn,et al.  Heuristic evaluation of a web-based interface for internet telemedicine. , 1999, Telemedicine journal : the official journal of the American Telemedicine Association.

[11]  Mattias Arvola,et al.  Defending Clinician Values: Quality-in-use of Decision Support Systems for Thoracic Surgery , 2002, AMIA.

[12]  David Classen,et al.  Implementing Antibiotic Practice Guidelines through Computer-Assisted Decision Support: Clinical and Financial Outcomes , 1996, Annals of Internal Medicine.

[13]  Sri Hastuti Kurniawan,et al.  Review of Interaction design , 2003 .

[14]  John E. Bennett,et al.  Principles and practice of infectious diseases. Vols 1 and 2. , 1979 .

[15]  Gary M Olson,et al.  Human-computer interaction: psychological aspects of the human use of computing. , 2003, Annual review of psychology.

[16]  V Sintchenko,et al.  What do physicians think about evidence‐based antibiotic use in critical care? A survey of Australian intensivists and infectious disease practitioners , 2001, Internal medicine journal.

[17]  M G Kahn,et al.  Contextual inquiry: discovering physicians' true needs. , 1995, Proceedings. Symposium on Computer Applications in Medical Care.

[18]  Bonnie Kaplan,et al.  Evaluating informatics applications - some alternative approaches: theory, social interactionism, and call for methodological pluralism , 2001, Int. J. Medical Informatics.

[19]  W P Kozinn,et al.  Computer-assisted antimicrobial surveillance in a community teaching hospital. , 1995, American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists.

[20]  A Kushniruk,et al.  Analysis of medical decision making: a cognitive perspective on medical informatics. , 1995, Proceedings. Symposium on Computer Applications in Medical Care.

[21]  David W. Bates,et al.  Synthesis of Research Paper: Ten Commandments for Effective Clinical Decision Support: Making the Practice of Evidence-based Medicine a Reality , 2003, J. Am. Medical Informatics Assoc..

[22]  J. Barenfanger,et al.  Improved Antimicrobial Interventions Have Benefits , 2001, Journal of Clinical Microbiology.

[23]  Raymond E. Levitt,et al.  The effects of CPOE on ICU workflow: an observational study , 2003, AMIA.

[24]  Claus Bossen,et al.  Ethnography in design: tool-kit or analytic science? , 2002 .

[25]  J. F. Cade,et al.  Antibiotic Prescribing in Response to Bacterial Isolates in the Intensive Care Unit , 2005, Anaesthesia and intensive care.

[26]  Karin A Thursky,et al.  Reduction of broad-spectrum antibiotic use with computerized decision support in an intensive care unit. , 2006, International journal for quality in health care : journal of the International Society for Quality in Health Care.

[27]  M T Inaraja,et al.  Computer-assisted antimicrobial-use monitoring. , 1986, American journal of hospital pharmacy.

[28]  Ann Blandford,et al.  Situation awareness in emergency medical dispatch , 2004, Int. J. Hum. Comput. Stud..

[29]  Larry L. Constantine,et al.  Software for Use - A Practical Guide to the Models and Methods of Usage-Centered Design , 1999 .